Phylogeny of cortical-hippocampal projections reveals selective elimination of input from sensory regions

Posted by dbos NTNU

Kavli Affiliate: Menno Witter | Authors: Daniel Reznik, Piotr Majka, Marcello GP Rosa, Menno P Witter and Christian F Doeller | Summary: The study of cross-species differences in the organization of the cerebral cortex received significant attention during the past century. However, the evolutionary principles governing changes in brain connectivity and their impact on cognition […]


Continue.. Phylogeny of cortical-hippocampal projections reveals selective elimination of input from sensory regions

GIAnT: a Glutamate Imaging Analysis Toolbox

Posted by dbos Hopkins

Kavli Affiliate: Adam S. Charles | Authors: Michael E. Xie, Johannes Friedrich, Elizabeth Wirsching, Caleb Jones Shibu, Maedeh Seyedolmohadesin, Naveen Ouellette, Tim Wang, Karel Svoboda, Adam S Charles and Kaspar Podgorski | Summary: Recent advances in fluorescent indicators and optical microscopy now enable in vivo synaptic imaging of glutamate, which transmits the majority of signals between neurons […]


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Bats decouple sonar gaze from steering to resolve sensory conflict

Posted by dbos Hopkins

Kavli Affiliate: Cynthia F. Moss | Authors: Nikita M Finger, Shivam S Chitnis, Grace Capshaw, Alara Kaplanoglu, Anand Krishnan and Cynthia F Moss | Summary: When sensory modalities yield conflicting information, animals must rapidly reassess stimuli to select their actions. We induced auditory–visual conflict in free-flying echolocating Egyptian fruit bats, by fitting animals with prisms […]


Continue.. Bats decouple sonar gaze from steering to resolve sensory conflict

Heterogeneous single-cell dynamics support stable population codes for objects in the mouse anterior cingulate cortex

Posted by dbos NTNU

Kavli Affiliate: Clifford Kentros | Authors: Lucie A.L. Descamps, Wesley P. Clawson, Miguel M. Carvalho, Thomas Rogerson, Omer Hazon, Oscar M.T. Chadney, Mark J. Schnitzer and Clifford Kentrosa | Summary: Remembering object locations is crucial for survival, yet how the anterior cingulate cortex (ACC) encodes spatial features across repeated experiences has not been fully characterized. […]


Continue.. Heterogeneous single-cell dynamics support stable population codes for objects in the mouse anterior cingulate cortex

Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis

Posted by dbos Rockefeller

Kavli Affiliate: Jean-Laurent Casanova | Authors: Diana Olguín Calderón, Laura E. Kilpatrick, Clément Conil, Quentin Philippot, Masato Ogishi, Joseph Vellutini, Ji Eun Han, Narelle Keating, Hailun Li, Geetha Rao, Jonathan Bohlen, Charles S. Lay, Simon Platt, Gaspard Kerner, Elsa Feredj, Jessica N. Peel, Mana Momenilandi, Yoann Seeleuthner, Candice Lainé, Camille Soudée, Claire Leloup, Cecile Debuisson, […]


Continue.. Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis

Coordination of turn-related activity in the superior colliculus with locomotor dynamics and hippocampal representations of possible futures

Posted by dbos UCSD / Salk, UCSF

Kavli Affiliate: Massimo Scanziani and Loren Frank | Authors: Cameron Wilhite, Loren M. Frank and Massimo Scanziani | Summary: Turning left or right is a core element of animal navigation. Such turns occur in precise coordination with the ongoing stepping rhythm and require internal planning for the animal’s future path. The superior colliculus (SC) is […]


Continue.. Coordination of turn-related activity in the superior colliculus with locomotor dynamics and hippocampal representations of possible futures

Smells like γ-synchrony: Insula-prefrontal communication depends on γ-synchrony and supports modality-specific changes in behavioral strategies

Posted by dbos UCSF

Kavli Affiliate: Vikaas Sohal | Authors: Lara L. Hagopian, Aarron J. Phensy, Austin J. Gallagher and Vikaas S. Sohal | Summary: The prefrontal cortex is critical for many aspects of flexible behavior, but how it interacts with other brain regions to perform this function remains largely unknown. The insula is bidirectionally coupled with prefrontal cortex […]


Continue.. Smells like γ-synchrony: Insula-prefrontal communication depends on γ-synchrony and supports modality-specific changes in behavioral strategies

Cell-type-specific cortical feedback coordinates hierarchical credit assignment

Posted by dbos Columbia

Kavli Affiliate: Rui Costa | Authors: Will Greedy, Heng Wei Zhu, Alexia Duriez, Joseph Pemberton, Patrick T. McCarthy, Kevin Kermani Nejad and Rui Ponte Costa | Summary: Learning is thought to arise from synaptic modifications embedded in brain-wide circuits 1–3, yet how such circuits coordinate plasticity to support complex behaviour is not known 4,5. Inspired […]


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Semaphorin 3A promotes resilience of sleep and cognition to brain injury

Posted by dbos UCSF

Kavli Affiliate: Jeanne Paz | Authors: Deanna Necula, Yuliya Voskobiynyk, Srujana Poluri and Jeanne T. Paz | Summary: Chronic sleep disruption and cognitive deficits are debilitating long-term consequences of traumatic brain injury (TBI), yet the endogenous mechanisms that drive network-level recovery remain poorly understood. Here, we demonstrate that during the chronic phase post-injury, network oscillations […]


Continue.. Semaphorin 3A promotes resilience of sleep and cognition to brain injury