Kavli Affiliate: Lily Jan and Yuh Nung Jan | Authors: Jing Hui Adeline J. H. Yong, Yuh Nung Jan, Yayu Wang, Juan A Oses-Prieto, Tong Cheng, Chao Chen, Mario V Zubia, Alma Burlingame, Lily Y Jan, Nicholas T Ingolia and J. Wren Kim | Summary: Synapses are dynamic structures whose protein composition remodels in response […]
Kavli Affiliate: Timothy Brown | Authors: Kristen C Ruegg, Christen M Bossu, Reza Goljani Amirkhiz, Nikunj Goel, Erica CN Robertson, Timothy M Brown, Kathryn Bernier, Ben J Vernasco, Peri E Bolton, Erik R Funk, Scott A Taylor, Mevin B Hooten and Erika S Zavaleta | Summary: Accelerated warming at high elevations is having a disproportionate […]
Kavli Affiliate: Massimo Scanziani and Jeanne Paz | Authors: Joshua M. Brenner, Sarah Ruediger, Cameron Wilhite, Josue M. Regalado, Yuta Senzai, Yuliya Voskobiynyk, Jeanne T. Paz, Massimo Scanziani and Riccardo Beltramo | Summary: Mammals rely on their senses to establish their position in space. Neural activity in the hippocampus maps position, yet how sensory signals […]
Kavli Affiliate: Pietro De Camilli | Authors: Devin M Fuller, Yumei Wu, Florian Schueder, Burha Rasool, Shanta Nag, Justin L. Korfhage, Rolando Garcia-Milian, Katerina D Melnyk, Joerg Bewersdorf, Pietro De Camilli and Thomas Melia | Summary: Autophagosomes form from seed membranes that expand through bulk-lipid transport via the bridge-like lipid transporter ATG2. The origins of […]
Kavli Affiliate: Nicola Allen | Authors: Krissy A Lyon, Adrien Paumier, Ananya Kandikonda, Andrea Melendez and Nicola J Allen | Summary: Astrocytes support neuronal function during development through secreted proteins, yet how astrocyte-secreted cues are altered in disease states and contribute to neurodevelopmental disorders remains poorly defined. Rett syndrome (RTT) is a regressive neurodevelopmental disorder […]
Kavli Affiliate: Justus M Kebschull | Authors: Huihui Qi, Manjari M-G Anant, Dylan Z Faltine-Gonzalez, Ruitao Hu, Lai Wei, Christopher D Workman, Caleb Shi, Ishbel Del Rosario and Justus M Kebschull | Summary: Understanding cellular identity requires multimodal measurements in single cells. Cellular barcoding provides powerful tools for recording the properties or history of individual […]
Kavli Affiliate: Patrick Kanold | Authors: Sahar Khosravi, Nikolas A. Francis, Patrick O. Kanold and Behtash Babadi | Summary: Understanding how neuronal populations interact to encode and transform sensory information is a fundamental challenge in computational neuroscience. Most existing studies, however, study neural encoding, behavioral readout, and functional connectivity as disjoint problems. Two-photon calcium imaging […]
Kavli Affiliate: Damon Clark | Authors: Malcom Díaz García, Jonathan Beagan, Ernesto Cabezas-Bou, Matthew J. Thomas, Sandeep Kumar, Lin Shao, Xingyang Fu, Andrea Cuentas-Condori, Jacqueline R. McVay, Josh D. Hawk, Andrew Lauziere, William Mohler, Hari Shroff, Damon Clark and Daniel A. Colón-Ramos | Summary: Sensory neurons must extract behaviorally relevant features from dynamic environments while […]
Kavli Affiliate: Jean-Laurent Casanova | Authors: Colin Kim, Maira Gaballa, Danyel Lee, Emmanuelle Jouanguy, Shen-Ying Zhang, Jean-Laurent Casanova and Ahmad Yatim | Summary: The binding of transmembrane (TM) ligands to their cognate TM receptors on neighboring cells governs intercellular adhesion and direct cell–cell communication. However, these interactions are difficult to study in vitro because they […]
Kavli Affiliate: Devanand Manoli | Authors: David M Young, Ruchira Sharma, Narjes Rohani, Chimmi Dema, Lindsay Liang, Bernie Devlin, Devanand S. Manoli and Stephan J SandersH. Janak | Summary: The past decade has seen tremendous progress in the identification of genes associated with complex neuropsychiatric disorders, including autism spectrum disorder (ASD) and schizophrenia. Expression patterns […]