Kavli Affiliate: David Kleinfeld | Authors: Aiman Alzetani, Jacob Duckworth, Anthony A Birch, David M Simpson, David Kleinfeld and Roxana O Carare | Summary: This study tests the hypothesis that vasomotion, an ∼ 0.1 Hz oscillation in arteriole diameter, is generated by intrinsic oscillations within the arterioles that perfuse the brain, and not by external […]
Kavli Affiliate: Xingde Li | Authors: Yuanwei Xu, Hyeoncheol Park, Jason Li, Yuehan Liu, T. Mamie Lih, Chengyu Lee, Xingde Li and hui Zhan | Summary: Spatial proteomics aims to characterize proteome in situ with regional resolution, linking molecular states to tissue architecture and microenvironments. While recent advances have expanded our access to spatially resolved […]
Kavli Affiliate: Reza Abbasi Asl | Authors: oseph Chih Chien Chen, Gabriella Mace, Avery Ostrand, Christian Valtierra, Sydney Griffith, Richard Campusano, Andrew Li, Erin Vinson, Jonas Schlomberg, Maya Eshel, John Matthew Suntay, Syed Rahim, Roger Anguera-Singla, Bijurika Nandi, Isabella Hartley, Daniel A Brown, Nicole C Swann, Luca Mazzucato, Xin Hu, Dan Zhang, Christopher Timmermann, Maryam […]
Kavli Affiliate: Deanna J. Greene | Authors: Hyejin J. Lee, Ally Dworetsky, Alexis Porter, Sihan Fei, Ashley N. Nielsen, Benjamin A. Seitzman, Babatunde Adeyemo, Patrick G. Bissett, Russell A. Poldrack, Jessica R. Cohen, Mark D’Esposito, Maital Neta, Nico U.F. Dosenbach, Steven E. Petersen, Evan M. Gordon, Deanna J. Greene and Caterina Gratton | Summary: Brain […]
Kavli Affiliate: Rui Costa and Darcy Peterka | Authors: Ines Rodrigues-Vaz, Vivek R. Athalye, Darcy S. Peterka and Rui M. Costa | Summary: The striatum is classically thought to modulate action vigor and reinforcement, but whether it specifies and controls ongoing actions at a fine scale remains unclear. Here, we test whether striatal activity can […]
Kavli Affiliate: Yuh Nung Jan | Authors: J. Wren Kim, Rebecca Eliscu, Adeline JH Yong, Sua Lee, Yuh Nung Jan, Taeyoung Hwang, Liana F Lareau and Nicholas T Ingolia | Summary: Neurons function within interconnected networks and must continuously adjust their firing properties to maintain stable network activity. Although these adjustments require long-lasting molecular changes, […]
Kavli Affiliate: Jeanne Paz | Authors: Isaac Y.M. Chang and Jeanne T. Paz | Summary: Coordinated movement relies on interactions between the basal ganglia and the thalamus, yet the circuits linking these structures are not fully understood. Here, we dissect a non-canonical basal ganglia output pathway, from the external globus pallidus (GPe) to the nucleus […]
Kavli Affiliate: Damon Clark | Authors: Harsh Vashistha, Natalia CB Matos, Heng Wu and Damon A Clark | Summary: Detecting approaching objects is essential for survival, and studies across animals have identified neurons and circuits selective for objects that grow in size over time, a hallmark of visual approach. However, approach as a physical process […]
Kavli Affiliate: Dhruv Grover | Authors: Woochan Choi, Shyam Srinivasan and Dhruv Grover | Summary: Learning often requires inference over hidden task structure, including features that predict outcomes. In mammals, prediction-error signaling by midbrain dopamine neurons is considered central to learning, but how these neurons reflect the progression and stability of learning remains unclear. Using […]
Kavli Affiliate: Leslie B. Vosshall | Authors: Umberto Palatini, Stéphanie Dabo, Adriana Rosas-Villegas, Yael N. Tsitohay, Alexandra E. DeFoe, Nadav Shai, Louis Lambrechts and Leslie B. Vosshall | Summary: Billions of people each year are at risk from infection by dengue, Zika, yellow fever, and chikungunya viruses, which are transmitted by female Aedes aegypti mosquitoes. […]