Stem cells tightly regulate dead cell clearance to maintain tissue fitness

Kavli Affiliate: Elaine Fuchs | Authors: Katherine S Stewart, Kevin AU Gonzales, Shaopeng Yuan, Matthew T Tierney, Alain R Bonny, Yihao Yang, Nicole R Infarinato, Christopher J Cowley, John M Levorse, H Amalia Pasolli, Sourav Ghosh, Carla V Rothlin and Elaine Fuchs | Summary: Macrophages and dendritic cells have long been appreciated for their ability […]


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The Heritability of Human Connectomes: a Causal Modeling Analysis

Kavli Affiliate: Joshua Vogelstein | Authors: Jaewon Chung, Eric W Bridgeford, Michael Powell, Derek Pisner and Joshua T Vogelstein | Summary: The heritability of human connectomes is crucial for understanding the influence of genetic and environmental factors on variability in connectomes, and their implications for behavior and disease. However, current methods for studying heritability assume […]


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A cross-species proteomic map of synapse development reveals neoteny during human postsynaptic density maturation

Kavli Affiliate: Arturo Alvarez-Buylla, Nenad Sestan, Alex Pollen, Arnold Kriegstein | Authors: Li Wang, Kaifang Pang, Li Zhou, Arantxa Cebrian-Silla, Susana Gonzalez-Granero, Shaohui Wang, Qiuli Bi, Matthew L. White, Brandon Ho, Jiani Li, Tao Li, Yonatan Perez, Eric J. Huang, Ethan A Winkler, Mercedes F Paredes, Rothem Kovner, Nenad Sestan, Alex A. Pollen, Pengyuan Liu, […]


Continue.. A cross-species proteomic map of synapse development reveals neoteny during human postsynaptic density maturation

Multicore fiber optic imaging reveals that astrocyte calcium activity in the cerebral cortex is modulated by internal motivational state

Kavli Affiliate: Jin Kang, Dwight Bergles | Authors: Yung-Tian A. Gau, Eric Hsu, Jaepyeong Cha, Rebecca W. Pak, Loren L. Looger, Jin U. Kang and Dwight E. Bergles | Summary: Astrocytes are a direct target of neuromodulators and can influence neuronal activity on broad spatial and temporal scales through their close proximity to synapses. However, […]


Continue.. Multicore fiber optic imaging reveals that astrocyte calcium activity in the cerebral cortex is modulated by internal motivational state

Neural dynamics and geometry for transitive inference

Kavli Affiliate: Vincent Ferrera, Daphna Shohamy, Larry Abbott | Authors: Kenneth Kay, Natalie Biderman, Ramin Khajeh, Manuel Beiran, Christopher J Cueva, Daphna Shohamy, Greg Jensen, Xue-Xin Wei, Vincent P Ferrera and L F Abbott | Summary: Relational cognition — the ability to infer relationships that generalize to novel combinations of objects — is fundamental to […]


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RNA- and ATAC-sequencing Reveals a Unique CD83+ Microglial Population Focally Depleted in Parkinson’s Disease

Kavli Affiliate: Rui Costa | Authors: Zena K Chatila, Archana Yadav, Jason Mares, Xena E Flowers, Taekyung D Yun, Mamunur Rashid, Ryan Talcoff, Zoe Pelly, Ya Zhang, Philip L De Jager, Andrew F Teich, Rui M Costa, Estela Area Gomez, Gabriela J Martins, Roy N Alcalay, Jean Paul Vonsattel, Vilas Menon, Elizabeth M Bradshaw and […]


Continue.. RNA- and ATAC-sequencing Reveals a Unique CD83+ Microglial Population Focally Depleted in Parkinson’s Disease

The emergence of human gastrulation upon in vitro attachment

Kavli Affiliate: Ali H. Brivanlou | Authors: Riccardo De Santis, Eleni Rice, Gist Croft, Min Yang, Edwin A. Rosado-Olivieri and Ali H. Brivanlou | Summary: While studied extensively in model systems, human gastrulation remains obscure. This process starts upon blastocyst implantation into the uterine wall, which is assumed to occur after 14 days post-fertilization. The […]


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Towards the biogeography of butyrate-producing bacteria

Kavli Affiliate: Robert Edwards | Authors: Joel E Brame, Craig Liddicoat, Catherine A Abbott, Robert A Edwards, Jake M Robinson, Nicolas E Gauthier and Martin F Breed | Summary: Butyrate-producing bacteria are found in many ecosystems and organisms, including humans, and are vital to ecosystem functionality and human health. These bacteria ferment organic matter, producing […]


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