Kavli Affiliate: Clifford Kentros | Authors: Oscar M. T. Chadney, Matteo Guardamagna, Felix Dorr, Lucie A. L. Descamps, Federico Stella, Francesco Battaglia and Clifford G. Kentros | Summary: The hippocampus and its main input, the entorhinal cortex, are essential for memory formation, yet how they interact to do so remains unresolved. Hippocampal CA1 pyramidal neurons […]
Kavli Affiliate: Wei Min | Authors: Xinwen Liu, Xuemeng Li, Lele Xu, Mian Wei, Areej Niaz, Ye He and Wei Min | Summary: Molecular information is vital for imaging technology. Optical imaging acquires molecular specificity almost exclusively via labeling strategy, which is fundamentally constrained by limited multiplexing capacity, high running costs, and experimental complexity. Conversely, […]
Kavli Affiliate: Robert Edwards | Authors: Cedric Lood, Swapnil Doijad, Evelien Adriaenssens, Yiming Bao, Jakub Barylski, Benjamin Bolduc, George Bouras, Rodney J. Brister, Titus C. Brown, Antonio Pedro Camargo, Lander De Coninck, Sebastian Deorowicz, Robert Edgar, Robert Edwards, Shitao Gong, Arthur Gruber, Adam Gudys, Ernestina Hauptfeld, Anneliek ter Horst, Tianyang Huang, Jingzhe Jiang, Lars Kaderali, […]
Kavli Affiliate: Alex Kolodkin | Authors: Natalie R Hamilton, Victoria N Neckles, Timour Al-Khindi, Nitya Donthi, Shun Mizutori, Renata Fu, James K Kiraly, Bea C Winship, Alex L Kolodkin and Karina Chaudhari | Summary: The optokinetic reflex (OKR) is an evolutionarily conserved reflexive behavior that ensures image stabilization on the retina during global motion. It […]
Kavli Affiliate: Daniel Mucida | Authors: Marwa Saad, Alexandra Thoms, Yue S. Yin, Izabela Mamede, Afsana Rahman, Ruonan Chen, Sebastian E. Carrasco, Patrick W. Darcy, Norihiro Goto, Sohail F. Tavazoie, Angelina M. Bilate and Daniel Mucida | Summary: Colorectal cancer (CRC) remains a leading cause of cancer mortality, with most cases refractory to immunotherapy. Distinguishing […]
Kavli Affiliate: Yifan Cheng | Authors: Chengmin Li, Wooyoung Choi, Hao Wu and Yifan Cheng | Summary: In single particle cryo-EM, analysis of continuous conformational heterogeneity has always been challenging. Both linear and deep learning-based methods treat conformational heterogeneity as perturbations to the consensus average conformation, limiting their capability in analyzing large protein motions. While […]
Kavli Affiliate: Mark H. Tuszynski | Authors: Gunnar H.D. Poplawski, Chase Weinholtz, Grace Woodruff, Ruhel Ahmad, Wyatt Bunner, Rodrigo Gonzales and Mark H. Tuszynski | Summary: Neural stem cell (NSC) transplantation is a promising strategy for repairing the injured spinal cord, but transplanted cells typically require immunosuppressive therapy to prevent rejection—even for induced pluripotent stem […]
Kavli Affiliate: Adam S. Charles and Patricia Janak | Authors: Aamna Lawrence, Eva Yezerets, Patricia H Janak and Adam Charles | Summary: Neural systems exhibit multiple firing states that reflect an organism’s internal state and modulate the relationship between external environmental stimuli and behavior. Several studies have inferred these latent states by supplementing the traditional […]
Kavli Affiliate: Anders Dale | Authors: Yanghee Im, Melody J.Y. Kang, Boris A. Gutman, Pravesh Parekh, Diliana Pecheva, Anders M. Dale, Ole A. Andreassen, Paul M. Thompson, Christopher R.K. Ching and for the ENIGMA Bipolar Disorder Working Groupz | Summary: Compared to traditional gross volumetrics, surface-based models provide greater spatial precision for understanding brain alterations […]
Kavli Affiliate: Robert Edwards | Authors: Anita Tarasenko, Bhavya Papudeshi, Van Nguyen, Susanna Rose Grigson, George Bouras, Vijini Mallawaarachchi, Abbey Louise, Kelly Hutton, Renee Green, Jack Ramsay, Hamza Hajama, Ana Georgina Cobian-Guemes, Anca Mara Segall, Morgyn Warner, Sarah Giles, Clarice Harker and Robert A Edwards | Summary: Achromobacter species are emerging multidrug-resistant (MDR) pathogens in people […]