Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

Kavli Affiliate: Denis Wirtz | Authors: Devon E Mason, Megan Goeckel, Sebastian L Vega, Pei-Hsun Wu, Dymonn Johnson, Su-Jin Heo, Denis Wirtz, Jason A Burdick, Levi Wood, Brain Y Chow, Amber N Stratman and Joel D Boerckel | Summary: Vascular morphogenesis requires persistent endothelial cell motility that is responsive to diverse and dynamic mechanical stimuli. […]


Continue.. Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

A low-resource reliable pipeline to democratize multi-modal connectome estimation and analysis

Kavli Affiliate: Brian Caffo Randal Burns Carey Priebe Joshua Vogelstein | Authors: Jaewon Chung, Ross Lawrence, Alexander Loftus, Gregory Kiar, Eric Bridgeford, Consortium for Reliability and Reproducibility, Vikram Chandrashekhar, Disa Mhembere, Sephira Ryman, Xi-Nian Zuo, Daniel Margulies, R. Cameron Craddock, Carey E. Priebe, Rex Jung, Vince D. Calhoun, Brian Caffo, Randal Burns, Michael P. Milham […]


Continue.. A low-resource reliable pipeline to democratize multi-modal connectome estimation and analysis

Conservation of neuron-astrocyte coordinated activity among sensory processing centers of the developing brain

Kavli Affiliate: Dwight Bergles | Authors: Vered Kellner, Patrick Parker, Xuelong Mi, Guoqiang Yu, Gesine Saher and Dwight E Bergles | Summary: Abstract Afferent neurons in developing sensory organs exhibit a prolonged period of burst firing prior to the onset of sensory experience. This intrinsically generated activity propagates from the periphery through central processing centers […]


Continue.. Conservation of neuron-astrocyte coordinated activity among sensory processing centers of the developing brain

Sliding windows analysis can undo the effects of preprocessing when applied to fMRI data

Kavli Affiliate: Martin Lindquist | Authors: Martin Lindquist | Summary: Resting-state fMRI (rs-fMRI) data is used to study the intrinsic functional connectivity (FC) in the human brain. Recently, interest has focused on studying the temporal dynamics of FC on short timescales, ranging from seconds to minutes. These studies of time-varying FC (TVFC) have enabled the […]


Continue.. Sliding windows analysis can undo the effects of preprocessing when applied to fMRI data

Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

Kavli Affiliate: Michael Miller | Authors: Paul Richard Yulo, Nicolas Desprat, Monica L. Gerth, Barbara Ritzl-Rinkenberger, Andrew D Farr, Yunhao Liu, Xue-Xian Zhang, Michael Miller, Felipe Cava, Paul B. Rainey and Heather L Hendrickson | Summary: Maintenance of rod-shape in bacterial cells depends on the actin-like protein MreB. Deletion of mreB from Pseudomonas fluorescens SBW25 […]


Continue.. Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

Tonotopic organization of auditory cortex in awake marmosets revealed by multi-modal wide-field optical imaging

Kavli Affiliate: Xiaoqin Wang | Authors: Xindong Song, Yueqi Guo, Chenggang Chen, Jong Hoon Lee and Xiaoqin Wang | Summary: Tonotopic organization of the auditory cortex has been extensively studied in many mammalian species using various methodologies and physiological preparations. Tonotopy mapping in primates, however, is more limited due to constraints such as cortical folding, […]


Continue.. Tonotopic organization of auditory cortex in awake marmosets revealed by multi-modal wide-field optical imaging

Activation of hypoactive parvalbumin-positive fast-spiking interneuron restores dentate inhibition to prevent epileptiform activity in the mouse intrahippocampal kainate model of temporal lobe epilepsy

Kavli Affiliate: Jin Kang | Authors: Sang-Hun Lee, Young-Jin Kang and Bret N Smith | Summary: Parvalbumin-positive (PV+) GABAergic interneurons in the dentate gyrus provide powerful perisomatic inhibition of dentate granule cells (DGCs) to prevent overexcitation and maintain the stability of dentate gyrus circuits. Most dentate PV+ interneurons survive status epilepticus, but surviving PV+ interneuron […]


Continue.. Activation of hypoactive parvalbumin-positive fast-spiking interneuron restores dentate inhibition to prevent epileptiform activity in the mouse intrahippocampal kainate model of temporal lobe epilepsy

Three-dimensional reconstruction of fetal rhesus macaque kidneys at single-cell resolution reveals complex inter-relation of structures

Kavli Affiliate: Denis Wirtz | Authors: Lucie Dequiedt, Andre Forjaz, Jamie O. Lo, Owen J McCarty, Pei-Hsun Wu, Avi Rosenberg, Denis Wirtz and Ashley L. Kiemen | Summary: Kidneys are among the most structurally complex organs in the body. Their architecture is critical to ensure proper function and is often impacted by diseases such as […]


Continue.. Three-dimensional reconstruction of fetal rhesus macaque kidneys at single-cell resolution reveals complex inter-relation of structures

Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage

Kavli Affiliate: Jean Fan | Authors: Katy Boerner, Philip D Blood, Jonathan C Silverstein, Matthew Ruffalo, Sarah A Teichmann, Gloria Pryhuber, Ravi S Misra, Jeffrey M Purkerson, Jean Fan, John W Hickey, Gesmira Molla, Chuan Xu, Yun Zhang, Griffin M Weber, Yashvardhan Jain, Danial Qaurooni, Yongxin Kong, Andreas Bueckle and Bruce W Herr II | […]


Continue.. Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage