Kavli Affiliate: Michael Miller | Authors: Sonya Kumar Bharathkar, Michael J. Miller and Beth M. Stadtmueller | Summary: Secretory (S) Immunoglobin (Ig) A is the predominant mucosal antibody, which mediates host interactions with commensal and pathogenic microbes, including Clostridioides difficile. SIgA adopts a polymeric IgA structure that is bound by secretory component (SC). Despite significance, […]

Kavli Affiliate: Michael Beer | Authors: Andreas R. Gschwind, Kristy S. Mualim, Alireza Karbalayghareh, Maya U. Sheth, Kushal K. Dey, Evelyn Jagoda, Ramil N. Nurtdinov, Wang Xi, Anthony S. Tan, Hank Jones, X. Rosa Ma, David Yao, Joseph Nasser, Ziga Avsec, Benjamin T. James, Muhammad S. Shamim, Neva C. Durand, Suhas S. P. Rao, Ragini […]

Kavli Affiliate: David Linden | Authors: Mary E Frith, Purna C Kashyap, David R Linden, Betty Theriault and Eugene B Chang | Summary: Gastrointestinal microbes modulate peristalsis and stimulate the enteric nervous system (ENS), whose development, as in the central nervous system (CNS), continues into the murine postweaning period. Given that adult CNS function depends […]

Kavli Affiliate: Patricia Janak | Authors: Kurt Michael Fraser, Val L Collins, Amy R Wolff, David J Ottenheimer, Kaisa N Bornhoft, Fiona Pat, Bridget J Chen, Patricia H Janak and Benjamin T Saunders | Summary: Adaptive behavior in a dynamic environment often requires rapid revaluation of stimuli that deviates from well-learned associations. The divergence between […]

Kavli Affiliate: Michael Beer | Authors: Hira Jabeen, Michael Beer, James Spencer, Marc W van der Kamp, H Adrian Bunzel and Adrian J Mulholland | Summary: MAntimicrobial resistance is a public health crisis. Limited understanding of the catalytic drivers in resistance-mediating enzymes such as β-lactamases hinders our ability to combat this crisis. Here, we dissect […]

Kavli Affiliate: Denis Wirtz | Authors: Jeanette A.I. Johnson, Genevieve L Stein-O’Brien, Max Booth, Randy Heiland, Furkan Kurtoglu, Daniel Bergman, Elmar Bucher, Atul Deshpande, Andre Forjaz, Michael Getz, Ines Godet, Melissa Lyman, John Metzcar, Jacob Mitchell, Andrew Raddatz, Heber L. Rocha, Jacobo Solorzano, Aneequa Sundus, Yafei Wang, Daniele M. Gilkes, Luciane T. Kagohara, Ashley L. […]

Kavli Affiliate: Seth Blackshaw | Authors: Nguyet Le, Trieu-Duc Vu, Isabella Palazzo, Ritvik Pulya, Yehna Kim, Seth Blackshaw and Thanh Hoang | Summary: Neurogenic competence is actively repressed in mature mammalian Muller glial cells, and previous studies have predicted that this is in part mediated by active Notch signaling. To determine whether global loss of […]

Kavli Affiliate: Jeremias Sulam | Authors: Helge J Zollner, Christopher B. Davies-Jenkins, Dunja B. Simicic, Assaf Tal, Jeremias Sulam and Georg Oeltzschner | Summary: Purpose: The interest in application and modeling of dynamic MRS has recently grown. Therefore, it is imperative to systematically investigate accuracy, precision, and uncertainty estimation of 2D modeling algorithms. 2D modeling […]

Kavli Affiliate: Kristina Nielsen Loyal Goff | Authors: Soraia Barao, Yijun Xu, Rachel Vistein, Loyal Goff, Kristina Nielsen, Byoung-Il Bae, Richard S. Smith, Christopher A Walsh, Genevieve Stein O Brien and Ulrich Muller | Summary: The neocortex varies in size and complexity among mammals due to the tremendous variability in the number and diversity of […]

Kavli Affiliate: Martin Lindquist | Authors: Brent William Stewart, Michael L Keaser, Hwiyoung Lee, Sarah M Margerison, Matthew A Cormie, Massieh Moayedi, Martin Lindquist, Shuo Chen, Brian N. Mathur and David A Seminowicz | Summary: Aberrant cognitive network activity and cognitive deficits are established features of chronic pain. However, the nature of cognitive network alterations […]