High-throughput glioblastoma-neurovascular assembloids model blood-tumor barrier disruption, tumor reprogramming and therapeutic efficacy

Posted by dbos Columbia, This Week: Neuroscience

Kavli Affiliate: Wei Min | Authors: Pei Zhuang, Shuai Gao, Benjamin Scott, Yibo Jia, Wei-Min Meng, Rui Yin, Xinyu Nie, Soniya Tamhankar, Sean Palecek, Ludovica Gaiaschi, Jorge L. Jimenez Macias, Shuichi Mizuno, Sean E Lawler, Eric Shusta, Martine LM Lamfers, Fengfeng Bei and Choi-Fong Cho | Summary: The blood-tumor barrier (BTB) in glioblastoma is an […]


Continue.. High-throughput glioblastoma-neurovascular assembloids model blood-tumor barrier disruption, tumor reprogramming and therapeutic efficacy

Cellular-resolution Three-photon Ultra-Deep Imaging (TrUDI) of neuronal population activity at 2 mm depth in the mammalian brain

Posted by dbos Rockefeller, This Week: Neuroscience

Kavli Affiliate: Alipasha Vaziri | Authors: Kalyan Santra, Francesca Logiacco, Agustina Frechou, Kevin Barber, Arash Bellafard, Jyun-you Liou and Alipasha Vaziri | Summary: Extending the depth reach of multi-photon microscopy for imaging neuronal population activity in the scattering mammalian brain is an exponentially hard problem. Three-photon (3p) microscopy has enabled imaging of neuroactivity at depths […]


Continue.. Cellular-resolution Three-photon Ultra-Deep Imaging (TrUDI) of neuronal population activity at 2 mm depth in the mammalian brain

TiSAM: fusing spatial and histopathology foundation models for whole-slide image segmentation

Posted by dbos Hopkins

Kavli Affiliate: Denis Wirtz | Authors: Zhiyuan Ding, Lucie Dequiedt, Marta Forjaz, Valentina Matos-Romero, Yu Shen, Talia Benducci, André Forjaz, Xiakoe Fei, Yutong Zhu, Patricia Nwoga, William Dhana, Julie Pascalin, Sam S. Lee, Luis Garza, Seung Hyun Lee, Edward J. Pierce, Marcia I. Canto, Jennifer P. Morton, Daniela Cihakova, Denis Wirtz, Data Science TeamLab and […]


Continue.. TiSAM: fusing spatial and histopathology foundation models for whole-slide image segmentation

Sex Differences in Human Music Perception are Negligible

Posted by klaurent Columbia

Kavli Affiliate: Sarah Woolley | Authors: Mila Bertolo, Daniel Müllensiefen, Isabelle Peretz, Sarah C. Woolley, Jon T. Sakata and Samuel A. Mehr | Summary: Since Darwin, researchers have proposed that human musicality evolved in a reproductive context in which males produce music to signal their mate quality to females. Sexually selected traits result from sex […]


Continue.. Sex Differences in Human Music Perception are Negligible

The chemosensory system of the clonal raider ant larva

Posted by dbos Rockefeller

Kavli Affiliate: Daniel Kronauer | Authors: Daniel H. Pastor, Leonora Olivos-Cisneros, Alejandra Hurtado-Giraldo, Anurag Sharma, Patrick K. Piekarski, Giacomo L. Glotzer and Daniel Kronauer | Summary: Ant larvae are blind and immobile, depending heavily on the adults for care in the form of feeding, grooming, and transport. However, they are not inactive colony members but […]


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Learning Interpretable Switching Dynamics in Shared Neural-Behavioral Latent Space

Posted by dbos Yale

Kavli Affiliate: Michael J Higley | Authors: Yongxu Zhang, Josue Ortega Caro, Rachel Oren, Michael James Higley, Jessica Cardin, Anne Churchland and Shreya Saxena | Summary: Modern recording technologies enable simultaneous measurement of high-dimensional neural activity and rich behavioral variables, creating both an opportunity and a modeling challenge: identifying the shared latent structure that mediates […]


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Disease-associated variants alter a novel physiological role of hnRNP H2 in neuronal development

Posted by dbos Columbia

Kavli Affiliate: Rui Costa | Authors: Afonso Lourinho, Marta S. Silva, Emanuel Tahiri, Marco D’Ambrosio, Ana D. Pinto, Saray Calvo Parra, Giovana De Pietro, Guilherme Galvao, Ana B. Caniceiro, Luis Pereira de Almeida, Paulo Pinheiro, Irina S. Moreira, Rui Jorge Nobre, Miranda Mele, Andrzej W. Cwetsch, Carlos B. Duarte and Rui O Costa | Summary: […]


Continue.. Disease-associated variants alter a novel physiological role of hnRNP H2 in neuronal development

WTR: A Toolkit for Functional Anterograde Transneuronal Circuit Mapping

Posted by dbos UCSF

Kavli Affiliate: Xin Duan and Lily Jan | Authors: Chao Chen, Ruogu Liu, Aijia Yi-Luo, Xiaoyan Cao, Jitao Hu, Shikang Guan, Si-yuan Chang, Xiaoli Cui, Wei Zhou, Fei Zhao, Chun-Teng Huang, Xin Duan, Lily Y. Jan and Tongfei A. Wang | Summary: The brain coordinates animal physiology and behavior via neuronal circuits. To understand and […]


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Reciprocal control of the stomach and intestine by viscerosensory neurons in caudal brainstem

Posted by dbos UCSF

Kavli Affiliate: Zachary Knight and Kevin Yackle | Authors: Naz Dundar, Ilayda Alkislar, Brooke C Jarvie, Ho Namkung, Kathryn Xie, Mahekdeep Kaur, Queenie Li, Anagh S Ravi, Alejandro Lopez, Antionette Spina, Longhui Qui, Truong Ly, Jun Oh, Kevin Yackle and Zachary A Knight | Summary: Digestion requires precisely timed transit of food through the gastrointestinal […]


Continue.. Reciprocal control of the stomach and intestine by viscerosensory neurons in caudal brainstem

Genetic accessibility, not superior fitness, determines which anti-HBs antibody escape variants are selected in patients

Posted by dbos Rockefeller

Kavli Affiliate: Charles M. Rice | Authors: Yingpu Yu, Eleftherios Michailidis, Leon Louis Seifert, Mengyin Zhang, Chenhui Zou, Catherine Freije, Georgios Dangas, Antonis Athanasiadis, Andreas Puschnik, Audrey Hanson, Evelyn Rocha, Yi-Pei Chen, Xupeng Hong, Corrine Quirk, Yichen Zhou, Michael A Schmid, Florian A Lempp, Charles M Rice, William Schneider and Ype P De Jong | […]


Continue.. Genetic accessibility, not superior fitness, determines which anti-HBs antibody escape variants are selected in patients