Kavli Affiliate: David Rowitch | Authors: Guy LAM, Zhaoyang Xu, Adrien M Vaquie, Stavros Vagionitis, Michael Perry, Omar de Faria, Jr., Georgios Solomou, John H Stockley, Gemma C Girdler, Daniel Yamamoto, Juan A Oses, Qianqian Zhang, Gregory Jordan, Laura R Morcom, Jacob Stillman, Hani S Mousa, Alma Burlingame, Murray Stewart, Hauke B. Werner, Andras Lakatos, […]
Kavli Affiliate: Nicola Allen | Authors: Krissy A Lyon, Adrien Paumier, Ananya Kandikonda, Andrea Melendez and Nicola J Allen | Summary: Astrocytes support neuronal function during development through secreted proteins, yet how astrocyte-secreted cues are altered in disease states and contribute to neurodevelopmental disorders remains poorly defined. Rett syndrome (RTT) is a regressive neurodevelopmental disorder […]
Kavli Affiliate: Justus M Kebschull | Authors: Huihui Qi, Manjari M-G Anant, Dylan Z Faltine-Gonzalez, Ruitao Hu, Lai Wei, Christopher D Workman, Caleb Shi, Ishbel Del Rosario and Justus M Kebschull | Summary: Understanding cellular identity requires multimodal measurements in single cells. Cellular barcoding provides powerful tools for recording the properties or history of individual […]
Kavli Affiliate: Patrick Kanold | Authors: Sahar Khosravi, Nikolas A. Francis, Patrick O. Kanold and Behtash Babadi | Summary: Understanding how neuronal populations interact to encode and transform sensory information is a fundamental challenge in computational neuroscience. Most existing studies, however, study neural encoding, behavioral readout, and functional connectivity as disjoint problems. Two-photon calcium imaging […]
Kavli Affiliate: Damon Clark | Authors: Malcom Díaz García, Jonathan Beagan, Ernesto Cabezas-Bou, Matthew J. Thomas, Sandeep Kumar, Lin Shao, Xingyang Fu, Andrea Cuentas-Condori, Jacqueline R. McVay, Josh D. Hawk, Andrew Lauziere, William Mohler, Hari Shroff, Damon Clark and Daniel A. Colón-Ramos | Summary: Sensory neurons must extract behaviorally relevant features from dynamic environments while […]
Kavli Affiliate: Jean-Laurent Casanova | Authors: Colin Kim, Maira Gaballa, Danyel Lee, Emmanuelle Jouanguy, Shen-Ying Zhang, Jean-Laurent Casanova and Ahmad Yatim | Summary: The binding of transmembrane (TM) ligands to their cognate TM receptors on neighboring cells governs intercellular adhesion and direct cell–cell communication. However, these interactions are difficult to study in vitro because they […]
Kavli Affiliate: Devanand Manoli | Authors: David M Young, Ruchira Sharma, Narjes Rohani, Chimmi Dema, Lindsay Liang, Bernie Devlin, Devanand S. Manoli and Stephan J SandersH. Janak | Summary: The past decade has seen tremendous progress in the identification of genes associated with complex neuropsychiatric disorders, including autism spectrum disorder (ASD) and schizophrenia. Expression patterns […]
Kavli Affiliate: Patricia Janak | Authors: Matilde Castro, Jingren Gu, Teresa Dong, David J. Ottenheimer, Céline Drieu and Patricia H. Janak | Summary: Prior studies implicate the central nucleus of the amygdala (CeA) in reward motivation, yet how this region encodes motivation for ethanol (EtOH) seeking and consumption–and how this compares to encoding of natural […]
Kavli Affiliate: Timothy Brown | Authors: Kristen C Ruegg, Christen M Bossu, Reza Goljani Amirkhiz, Nikunj Goel, Erica Robertson, Timothy M Brown, Kathryn Bernier, Ben J Vernasco, Peri E Bolton, Erik R Funk, Scott A Taylor, Mevin B Hooten and Erica S Zavaleta | Summary: Accelerated warming at high elevations is having a disproportionate impact […]
Kavli Affiliate: Loren Frank | Authors: Joseph Park, Cameron Smith, Shih Yi Tseng, Jennifer Guidera, Andrei V Semenov, Stanislav Smirnov, Loren M Frank and Gerald M Pao | Summary: Complex systems such as brains and other interacting biological and physical processes are difficult to represent because they evolve across many variables, scales, and nonlinear interactions. […]