Kavli Affiliate: Mounya Elhilali | Authors: Bernhard Englitz, Sahar Akram, Mounya Elhilali and Shihab Shamma | Summary: SPerception can be highly dependent on stimulus context, but whether and how sensory areas encode the context remains uncertain. We used an ambiguous auditory stimulus – a tritone pair – to investigate the neural activity associated with a […]
Kavli Affiliate: Solomon Snyder | Authors: Robin Roychaudhuri, Timothy West, Soumyaroop Bhattacharya, Harry Saavedra, Lauren Albacarys, Moataz M Gadalla, Leon Mario Amzel, Peixin Yang and Solomon H. Snyder | Summary: D-amino acids are being recognized in mammals as important molecules with function. This is a first identification of endogenous D-cysteine in mammalian pancreas. D-cysteine is […]
Kavli Affiliate: Terrence Sejnowski | Authors: Thomas M Bartol, Mariam Ordyan, Terrence J Sejnowski, Padmini Rangamani and Mary B Kennedy | Summary: Long-term potentiation (LTP) is a biochemical process in excitatory glutamatergic synapses in the Central Nervous System (CNS). It is initiated by a bout of synaptic activation that is strong enough to contribute to […]
Kavli Affiliate: Vikram Chib | Authors: Grace E Steward and Vikram S Chib | Summary: Feelings of cognitive fatigue emerge through repeated mental exertion and are ubiquitous in our daily lives. However, there is a limited understanding of the neurobiological mechanisms underlying the influence of cognitive fatigue on decisions to exert. We use functional magnetic […]
Kavli Affiliate: Denis Wirtz | Authors: Wenxuan Du, Bryan Zhou, André Forjaz, Sarah M. Shin, Fan Wu, Ashleigh J. Crawford, Praful R. Nair, Adrian C. Johnston, Hoku West-Foyle, Ashley Tang, Dongjoo Kim, Rong Fan, Ashley L. Kiemen, Pei-Hsun Wu, Jude M. Phillip, Won Jin Ho, David E. Sanin and Denis Wirtz | Summary: Enrichment of […]
Kavli Affiliate: Denis Wirtz | Authors: Wenxuan Du, Bryan Zhou, André Forjaz, Sarah M. Shin, Fan Wu, Ashleigh J. Crawford, Praful R. Nair, Adrian C. Johnston, Hoku West-Foyle, Ashley Tang, Dongjoo Kim, Rong Fan, Ashley L. Kiemen, Pei-Hsun Wu, Jude M. Phillip, Won Jin Ho, David E. Sanin and Denis Wirtz | Summary: Enrichment of […]
Kavli Affiliate: Andrea Hasenstaub | Authors: Calvin T Foss, Timothy Olsen, James Bigelow and Andrea R Hasenstaub | Summary: GABAergic interneurons, including somatostatin (SST) and vasoactive intestinal peptide (VIP) positive cells, play a crucial role in cortical circuit processing. Cre recombinase-mediated manipulation of these interneurons is facilitated by commercially available knock-in mouse strains such as […]
Kavli Affiliate: Edward Callaway | Authors: Rachel M. Cassidy, Angel V. Macias, Willian N. Lagos, Chiamaka Ugorji and Edward M. Callaway | Summary: Corticocortical (CC) projections in the visual system facilitate the hierarchical processing of sensory information. In addition to direct CC connections, indirect cortico-thalamo-cortical (CTC) pathways through the pulvinar nucleus of the thalamus can […]
Kavli Affiliate: Mark Churchland | Authors: Sean M. Perkins, Elom A. Amematsro, John P. Cunningham, Qi Wang and Mark M. Churchland | Summary: Decoders for brain-computer interfaces (BCIs) assume constraints on neural activity, chosen to reflect scientific beliefs while yielding tractable computations. Recent scientific advances suggest that the true constraints on neural activity, especially its […]
Kavli Affiliate: Ann McDermott | Authors: Cassandra A Chartier, Virgil A Woods, Yunyao Xu, Anne E van Vlimmeren, Marko Jovanovic, Ann E McDermott, Daniel A Keedy and Neel H Shah | Summary: The rapid identification of protein-protein interactions has been significantly enabled by mass spectrometry (MS) proteomics-based methods, including affinity purification-MS, crosslinking-MS, and proximity-labeling proteomics. […]