dbos – Kavli Institute Pre-Print Publications

Disrupting SORL1-retromer endosomal recycling in mice drives the age-dependent neurodegenerative signature of Alzheimer’s disease

Posted by dbos October 31, 2026November 4, 2026Columbia, This Week: Neuroscience

Kavli Affiliate: Scott Small | Authors: Yasir H. Qureshi, Jia Guo, John H Rinald, Zongyu Li, Rajesh Kumar Soni, Ananya Govindarajan, Emily Tortora, Genoveva Uzunova, Yanting Yang, Suvarnambiga Kannan, Priyanka Nanayakkara, Carol M Troy and Scott A Small | Summary: MRI studies have mapped the atrophic signature that distinguishes Alzheimer’s disease (AD), isolating regions differentially […]

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A parasitoid overcomes collective defense by silencing host communication

Posted by dbos October 30, 2026November 4, 2026Rockefeller, This Week: Neuroscience

Kavli Affiliate: Daniel Kronauer | Authors: Zheng-WU Wang, Chao Ye, Yi Zhong, Jin Zhao, Bo Zhang, Xinhai Ye, Kerry Oliver, Daniel Kronauer and Jin-Jun Wang | Summary: Gregarious insects communicate to coordinate group responses to danger, such as parasitoid attack. While parasitoids manipulate individual hosts through diverse virulence mechanisms, it remains unknown whether they can […]

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Analysis of sperm processing and cryopreservation procedures in the common marmoset (Callithrix jacchus) to reduce fragmentation and maximize total and progressive motility

Posted by dbos October 30, 2026November 4, 2026Hopkins, This Week: Neuroscience

Kavli Affiliate: Richard Huganir and Xiaoqin Wang | Authors: Rebecca A Holton, Joshua T Brennan, Sophia I Lipari, James Pickel, Nia Denney, Bhuchitra Singh, Jinwoo Jun, Yang Zhang, Colin D Robertson, Pan P Li, Ingie Hong, Richard L Huganir, Reza Kalhor, Christopher A Ross, James H Segars and Xiaoqin Wang | Summary: The marmoset has […]

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Multi-region two-photon calcium imaging in freely moving animals

Posted by dbos October 29, 2026November 4, 2026NTNU, This Week: Neuroscience

Kavli Affiliate: Jonathan Whitlock | Authors: Embla Kjellevold-Skallerud, Shouwen Ma, Julija Arbaciauskaite, Rajat Saxena, Antonio Lorca Camara, Klaus Joran Jenssen, Jonathan Robert Whitlock, Gahr Manfred and Weijian Zong | Summary: Complex behaviors emerge from the coordinated activity of neural circuits distributed across widely separated brain regions. Existing optical approaches for monitoring neural activity lack the […]

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Spontaneous neural activity in the developing ant olfactory system

Posted by dbos October 29, 2026November 4, 2026Rockefeller, This Week: Neuroscience

Kavli Affiliate: Daniel Kronauer | Authors: Dominic D Frank and Daniel J. C. Kronauer | Summary: Spontaneous neural activity is a pillar of mammalian neurodevelopment. In mammals, developing olfactory sensory neurons (OSNs) show spontaneous activity patterns that depend on the olfactory receptor (OR) they express. This activity is necessary for proper sorting of OSN axons […]

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Cholinergic and adrenergic modulation sculpts parallel inhibition of SST-INs in visual cortex

Posted by dbos October 28, 2026November 4, 2026This Week: Neuroscience, Yale

Kavli Affiliate: Michael J Higley | Authors: Jyoti Gupta, Chiayu Chiu, Fabio Veneto, Julijana Gjorgjieve and Michael Higley | Summary: neocortex. A growing literature has highlighted the role of somatostatin-expressing interneurons (SST-INs) in regulating cortical activity, and inhibition of SST-INs by other interneurons has emerged as a circuit motif leading to disinhibition of pyramidal neurons. […]

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A new neural code for position: generalizable spatial maps in mouse medial frontal cortex

Posted by dbos October 28, 2026November 4, 2026Columbia, This Week: Neuroscience

Kavli Affiliate: Richard Axel and Stefano Fusi | Authors: Rajyashree Sen, Lorenzo Posani, Alexander Medoff, Baihe Zhang, LF Abbott, Richard Axel and Stefano Fusi | Summary: Navigation requires the brain to encode spatial relationships that support extrapolation from explored to unexplored regions of space. We identified a novel neural code for space in the mouse […]

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Manta and devil ray genome assemblies uncover signatures of pelagic adaptation

Posted by dbos October 28, 2026November 4, 2026Rockefeller, This Week: Neuroscience

Kavli Affiliate: Erich Jarvis | Authors: Lea Soler Clavel, Manu Kumar Gundappa, Atlantine Boggio-Pasqua, Kim Bassos-Hull, Lisa Hoopes, Szu-Hsuan Lee, Marta Gut, Jessica Gomez Garrido, Fernando Cruz, Tyler S Alioto, Tatiana Tilley, Nivesh Jain, Jennifer Balacco, Conor Whelan, Dominic E Absolon, Linelle Abueg, Bonhwang Koo, Giulio Formenti, Olivier Fedrigo, Erich D Jarvis, Gavin Naylor, Daniel […]

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Memory erasure by dopamine-gated retrospective learning

Posted by dbos October 27, 2026November 4, 2026Hopkins, This Week: Neuroscience

Kavli Affiliate: Patricia Janak | Authors: Huijeong Jeong, Leo Zsembik, Farah Farouq, Risha Chakraborty, Nishita Belur, Mingkang Zhou, Andrea D. Sanders, Styra X. Wang, Ananya Srinivasan, Sylvia M. L. Cox, Eric Garr, Sara Brooke, Patricia H. Janak, Marco Leyton, Ritchie Chen and Vijay Mohan K. Namboodiri | Summary: Erasing outdated memories is crucial for adaptive […]

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Assessing nonlinear associations between body mass index and brain microstructure across adolescence in the ABCD Study

Posted by dbos October 27, 2026November 4, 2026This Week: Neuroscience, UCSD / Salk

Kavli Affiliate: Anders Dale | Authors: Alison Rigby, Diliana Pecheva, Pravesh Parekh, Diana M. Smith, Ashley Becker, Janosch Linkersdoerfer, Richard Watts, Robert Loughnan, Donald J. Hagler, Kyung E. Rhee, Carolina Makowski, Anders M. Dale and Terry L. Jernigan | Summary: Abstract Importance Adolescent body mass index (BMI) is linked to brain microstructural alterations, but it is […]

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