UCSF – Kavli Institute Pre-Print Publications

Single-library chromosome-scale diploid assemblies of vole genomes resolve a species-specific duplication implicated in pair bonding

Posted by dbos July 23, 2026July 27, 2026This Week: Neuroscience, UCSF

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Devanand Manoli | Authors: Mohamed Abuelanin, Gulhan Kaya, Juniper A Lake, Christine Lambert, Melody V Wu, Kristen Berendzen, Ksenia Krasheninnikova, Jonathan MD Wood, Nancy G Solomon, Zoe R Donaldson, Karen L Bales, Kerstin Howe, Jonas Korlach, Devanand S Manoli, Jessica […]

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Disruption of theta-timescale spiking impairs learning but spares hippocampal replay

Posted by dbos July 23, 2026July 27, 2026This Week: Neuroscience, UCSF

Kavli Affiliate: Loren Frank | Authors: Abhilasha Joshi, Alison E. Comrie, Samuel Bray, Abhijith Mankili, Jennifer A. Guidera, Rhino Nevers, Xulu Sun, Emily Monroe, Viktor Kharazia, Ryan Ly, Daniela Astudillo Maya, Denisse Morales-Rodriguez, Jai Yu, Anna Kiseleva, Victor Perez and Loren M. Frank | Summary: The ability to rapidly learn and retrieve salient information about […]

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A multimodal interrogation of Broca’s area in the pediatric and adult human brain

Posted by dbos July 23, 2026July 27, 2026This Week: Neuroscience, UCSF

Kavli Affiliate: Arturo Alvarez-Buylla, Arnold R. Kriegstein and David Rowitch | Authors: Juan Moriano, Tanzila Mukhtar, Jimmy Tsz Hang Lee, Fani Memi, Jonathan Augustin, Rachel Leonard, Joseph Asfouri, I-Ling Lu, Clara Siebert, Jennifer Ja-Yoon Choi, Guolong Zuo, Yinshui Chang, Stanislaw Makarchuk, Elina Jin, Martin Prete, Shaohui Wang, Qiuli Bi, Yuhan Hao, Liz Tuck, Katy Tudor, […]

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Device-embedded accelerometry complements neural signals for tracking parkinsonian motor states

Posted by dbos July 9, 2026July 20, 2026UCSF

Kavli Affiliate: Philip Starr | Authors: TAO LIU, Jiaang Yao, Bahman Abdi-Sargezeh, Abhinav Sharma, Camille Lasbareilles, Robert Tsi Lok Ho, Jackson Cheung, Timothy Denison, Huiling Tan, Wolf-Julian Neumann, Minghan Max Zhu, Sebastian Liu, Philip Starr, Simon Little and Ashwini Oswal | Summary: Adaptive deep brain stimulation (aDBS) relies on physiological biomarkers to infer motor state […]

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Psilocybin selectively rescues cognitive flexibility impairments caused by aberrant prefrontal error signalin

Posted by dbos July 9, 2026July 20, 2026UCSF

Kavli Affiliate: Vikaas Sohal | Authors: Christine Liu, Ellie M Ho, Alexander S Enos, Urte Beatrice Baublyte, Isabel M Luna, Alexander R Kosche and Vikaas S Sohal | Summary: Psychedelic drugs show remarkable potential for treating psychiatric disorders, but the mechanisms underlying their therapeutic effects remain relatively unknown. Here, we demonstrate that psilocybin can powerfully […]

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Opposing GIPR brainstem circuits differentially control feeding behaviour

Posted by dbos July 8, 2026July 20, 2026UCSF

Kavli Affiliate: Zachary Knight | Authors: Natalie S Figueredo Burgos, Alejandro Lopez-Cruz, Cecilia Skoug, Anna G Roberts, Kathryn Xie, Iona Davies, Norio Harada, Nobuya Inagaki, Frank Reimann, Fiona M Gribble, Ben Jones, Daniel I Brierley, Stefan Trapp, Zachary A Knight and Alice E Adriaenssens | Summary: Central glucose-dependent insulinotropic polypeptide receptor (GIPR) signalling is required […]

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Semaphorin 3A promotes resilience of sleep and cognition to brain injury

Posted by dbos July 7, 2026July 13, 2026UCSF

Kavli Affiliate: Jeanne Paz | Authors: Deanna Necula, Yuliya Voskobiynyk, Srujana Poluri and Jeanne T. Paz | Summary: Chronic sleep disruption and cognitive deficits are debilitating long-term consequences of traumatic brain injury (TBI), yet the endogenous mechanisms that drive network-level recovery remain poorly understood. Here, we demonstrate that during the chronic phase post-injury, network oscillations […]

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First community challenge for automated virus taxonomy

Posted by dbos July 6, 2026July 20, 2026UCSF

Kavli Affiliate: Robert Edwards | Authors: Cedric Lood, Swapnil Doijad, Evelien Adriaenssens, Yiming Bao, Jakub Barylski, Benjamin Bolduc, George Bouras, Rodney J. Brister, Titus C. Brown, Antonio Pedro Camargo, Lander De Coninck, Sebastian Deorowicz, Robert Edgar, Robert Edwards, Shitao Gong, Arthur Gruber, Adam Gudys, Ernestina Hauptfeld, Anneliek ter Horst, Tianyang Huang, Jingzhe Jiang, Lars Kaderali, […]

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CryoROLE: describing large inter-domain rotation in single particle cryo-EM

Posted by dbos July 4, 2026July 13, 2026UCSF

Kavli Affiliate: Yifan Cheng | Authors: Chengmin Li, Wooyoung Choi, Hao Wu and Yifan Cheng | Summary: In single particle cryo-EM, analysis of continuous conformational heterogeneity has always been challenging. Both linear and deep learning-based methods treat conformational heterogeneity as perturbations to the consensus average conformation, limiting their capability in analyzing large protein motions. While […]

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Host species background, defence systems, and phage tail gene architecture shape phage infectivity in cystic fibrosis-associated Achromobacter

Posted by dbos July 1, 2026July 13, 2026UCSF

Kavli Affiliate: Robert Edwards | Authors: Anita Tarasenko, Bhavya Papudeshi, Van Nguyen, Susanna Rose Grigson, George Bouras, Vijini Mallawaarachchi, Abbey Louise, Kelly Hutton, Renee Green, Jack Ramsay, Hamza Hajama, Ana Georgina Cobian-Guemes, Anca Mara Segall, Morgyn Warner, Sarah Giles, Clarice Harker and Robert A Edwards | Summary: Achromobacter species are emerging multidrug-resistant (MDR) pathogens in people […]

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