Neuroscience – Page 5 – Kavli Institute Pre-Print Publications

Early auditory and adult mating experiences interact with singer identity to shape neural responses to song in female zebra finches

Posted by dbos October 7, 2024October 21, 2024Columbia

Kavli Affiliate: Sarah Woolley | Authors: Isabella Catalano and Sarah C Woolley | Summary: Social and sensory experiences across the lifespan can shape social interactions, however, experience-dependent plasticity is widely studied within discrete life stages. In the socially monogamous zebra finch, in which females use learned vocal signals to identify individuals and form long-lasting pair […]

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Discovering Cognitive Strategies with Tiny Recurrent Neural Networks

Posted by dbos October 5, 2024October 14, 2024UCSD / Salk

Kavli Affiliate: Marcelo Mattar | Authors: Li Ji-An, Marcus K Benna and Marcelo G Mattar | Summary: Normative modeling frameworks such as Bayesian inference and reinforcement learning provide valuable insights into the fundamental principles governing adaptive behavior. While these frameworks are valued for their simplicity and interpretability, their reliance on few parameters often limits their […]

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Complete sequencing of ape genomes

Posted by dbos October 5, 2024October 14, 2024Rockefeller

Kavli Affiliate: Erich Jarvis | Authors: DongAhn Yoo, Arang Rhie, Prajna Hebbar, Francesca Antonacci, Glennis A. Logsdon, Steven J. Solar, Dmitry Antipov, Brandon D. Pickett, Yana Safonova, Francesco Montinaro, Yanting Luo, Joanna Malukiewicz, Jessica M. Storer, Jiadong Lin, Abigail N. Sequeira, Riley J. Mangan, Glenn Hickey, Graciela Monfort Anez, Parithi Balachandran, Anton Bankevich, Christine R. […]

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Why do we have so many excitatory neurons?

Posted by dbos October 5, 2024October 14, 2024Hopkins

Kavli Affiliate: Carey Priebe and Joshua Vogelstein | Authors: Qingyang Wang, Albert Cardona, Marta Zlatic, Joshua Vogelstein and Carey Priebe | Summary: Approximately four in five neurons are excitatory. This is true across functional regions and species. Why do we have so many excitatory neurons? Little is known. Here we provide a normative answer to […]

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Quantifying transcriptome turnover on phylogenies by modeling gene expression as a binary trait

Posted by dbos October 4, 2024October 14, 2024Rockefeller

Kavli Affiliate: Li Zhao | Authors: Ammon Thompson, Michael R. May, Ben Hopkins, Nerisa Riedl, Olga Barmina, Benjamin J. Liebeskind, Li Zhao, David Begun and Artyom Kopp | Summary: Changes in gene expression are a key driver of phenotypic evolution, leading to a persistent interest in the evolution of transcriptomes. Traditionally, gene expression is modeled […]

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Bi-level Graph Learning Unveils Prognosis-Relevant Tumor Microenvironment Patterns in Breast Multiplexed Digital Pathology

Posted by dbos October 4, 2024October 14, 2024Hopkins

Kavli Affiliate: Jeremias Sulam | Authors: Zhenzhen Wang, Cesar A. Santa-Maria, Aleksander S. Popel and Jeremias Sulam | Summary: The tumor microenvironment is widely recognized for its central role in driving cancer progression and influencing prognostic outcomes. There have been increasing efforts dedicated to characterizing this complex and heterogeneous environment, including developing potential prognostic tools […]

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Robust Detection of Brain Stimulation Artifacts in iEEG Using Autoencoder-Generated Signals and ResNet Classification

Posted by dbos October 2, 2024October 14, 2024UCSF

Kavli Affiliate: Edward Chang | Authors: Jeremy Saal, Ankit N. Khambhati, Edward F. Chang and Prasad Shirvalkar | Summary: Background Intracranial EEG (iEEG) is crucial for understanding brain function, but stimulation-induced noise complicates data interpretation. Traditional artifact detection methods require manual user input or struggle with noise variability, especially with limited labeled data. Objective We […]

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Like mother, like daughter? Phenotypic plasticity, environmental covariation, and heritability of size in a parthenogenetic wasp

Posted by klaurent October 1, 2024October 14, 2024UCSD / Salk

Kavli Affiliate: William Kristan | Authors: Alicia Tovar, Scott Monahan, Adrian Kristan, Walker Welch, Ryan Dettmers, Camila Arce, Theresa Buck, Michele Ruben, Alexander Rothenberg, Roxane Saisho, Ryan Cartmill, Timothy Skaggs, Robert Reyes, MJ Lee, John J Obrycki, William Kristan and Arun Sethuraman | Summary: Abstract Dinocampus coccinellae (Hymenoptera:Braconidae, Euphorinae) is a solitary, generalist Braconid parasitoid […]

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Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing

Posted by dbos October 1, 2024October 14, 2024Columbia

Kavli Affiliate: Liam Paninski | Authors: Marcus A Triplett, Marta Gajowa, Benjamin Antin, Masato Sadahiro, Hillel Adesnik and Liam Paninski | Summary: Discovering how neural computations are implemented in the cortex at the level of monosynaptic connectivity requires probing for the existence of synapses from possibly thousands of presynaptic candidate neurons. Two-photon optogenetics has been […]

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Long-Term Effects of Early Adolescent Second-Generation Antipsychotic Exposure on Body Weight, Caloric Intake, and Metabolism-Associated Gene Expression

Posted by dbos October 1, 2024October 14, 2024Rockefeller

Kavli Affiliate: Michael W. Young | Authors: Paul Soto, Michael E Young, Serena Nguyen, Megan Federoff, Mia M Goodson, Christopher D Morrison, Heidi Batdorf, Susan Burke and Jason Collier | Summary: The use of second-generation antipsychotic (SGA) medications in pediatric patients raises concerns about potential long-term adverse outcomes. The current study evaluated the long-term effects […]

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