Tactile responses in the mouse perirhinal cortex show invariance to physical features of the stimulus

Kavli Affiliate: Maximiliano Jose Nigro | Rejwan Hamza Farhad Salih, Luis Fernando Cobar, Francois Philippe Pauzin, Davide Zoccolan and Maximiliano Jose Nigr | Summary: Abstract Sensory processing in the cortex follows a hierarchical structure, transforming fine-grained stimulus features into abstract, invariant representations. These transformations have typically been characterised in visual pathways ranging from primary visual […]


Continue.. Tactile responses in the mouse perirhinal cortex show invariance to physical features of the stimulus

Transcriptional Interference Gates Monogenic Odorant Receptor Expression in Ants

Kavli Affiliate: Daniel Kronauer | Giacomo Leon Glotzer, P. Daniel H. Pastor and Daniel J. C. Kronauer | Summary: Communication is crucial to social life, and in ants, it is mediated primarily through olfaction. Ants have more odorant receptor (OR) genes than any other group of insects, generated through tandem duplications that produce large genomic […]


Continue.. Transcriptional Interference Gates Monogenic Odorant Receptor Expression in Ants

A predicted structural interactome reveals binding interference from intrinsically disordered regions

Kavli Affiliate: Li Zhao | Junhui Peng and Li Zhao | Summary: Proteins function through dynamic interactions with other proteins in cells, forming complex networks fundamental to cellular processes. While high-resolution and high-throughput methods have significantly advanced our understanding of how proteins interact with each other, the molecular details of many important protein-protein interactions are […]


Continue.. A predicted structural interactome reveals binding interference from intrinsically disordered regions

An Anterior Cingulate Cortex Neuronal Ensemble Controls Contextual Opioid Analgesic Tolerance

Kavli Affiliate: Marina Picciotto | Rafael E Perez, Yann S Mineur, Cheryl Chen, Wenliang Zhou, Julian Lee Thompsom, Saagar S Motupally, Angelica Minier-Toribio and Marina R Picciotto | Summary: Despite well-established cellular and molecular adaptations, opioid analgesic tolerance can be rapidly reversed in settings where these drugs are not expected. The specific neuronal populations that […]


Continue.. An Anterior Cingulate Cortex Neuronal Ensemble Controls Contextual Opioid Analgesic Tolerance

Neuromodulator control of energy reserves in dopaminergic neurons

Kavli Affiliate: Timothy A. Ryan | Camila Pulido, Matthew S. Gentry and Timothy A. Ryan | Summary: The brain is a metabolically vulnerable organ as neurons have both high resting metabolic rates and the need for local rapid conversion of carbon sources to ATP during activity. Midbrain dopamine neurons are thought to be particularly vulnerable […]


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Dynamic representation of sound locations during task engagement in marmoset auditory cortex

Kavli Affiliate: Patricia Janak | Shivam Kalhan, Robin Magnard, Yifeng Cheng and Patricia H. Janak | Summary: In auditory cortex, neural responses to stimuli inside receptive fields (RFs) can be further facilitated by behavioral demands, such as attending to a spatial location. It is less clear how off-RF stimuli modulate neural responses and contribute to […]


Continue.. Dynamic representation of sound locations during task engagement in marmoset auditory cortex

Uncertainty and reward histories have distinct effects on decisions after wins and losses

Kavli Affiliate: Patricia Janak | Shivam Kalhan, Robin Magnard, Yifeng Cheng and Patricia H. Janak | Summary: Intelligent behavior necessitates an adaptive integration of feedback. It is well-known that animals asymmetrically learn from positive and negative feedback. While asymmetrical learning is a robust behavioral effect, the latent computations behind how animals represent their environments and […]


Continue.. Uncertainty and reward histories have distinct effects on decisions after wins and losses

Neuroanatomical Basis of Coma in Acute Ischemic Stroke

Kavli Affiliate: Michael W. Young | Zheng Zhang, Milo White, Jennifer A Kim, Victor M Torres-Lopez, Aya Khalaf, David Jin, Aaron D Boes, Brian L Edlow, Stephen W English, David Fischer, Joel Geerling, Saleem M Halablab, Maarten G Lansberg, Margy McCullough-Hicks, James F Meschia, Patrik L Michel, Paola Palazzo, Benjamin D Reasoner, Robert W Regenhardt, […]


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Genomic resources for comparative analyses of obligate avian brood parasitism

Kavli Affiliate: Erich Jarvis | Authors: Rachel A Carroll, Edward Stallknecht Ricemeyer, LaDeana W Hillier, Jeffrey M DaCosta, Ekaterina Osipova, Sara Smith, Gabriel Jamie, Juan Gabriel Martinez, Mercedes Molina-Morales, Tomas Marques-Bonet, Joseph D Manthey, Diana Haddad, Matthew J Fuxjager, Kathleen S Lynch, Jonathan M.D. Wood, Erich Jarvis, Patrick Masterson, Francoise Thibaud-Nissen, Mark Hauber, Claire N […]


Continue.. Genomic resources for comparative analyses of obligate avian brood parasitism

Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS)

Kavli Affiliate: Alexander Szalay | Authors: Tricia R Cottrell, Jeffrey S Roskes, Michael Fotheringham, Emily Cohen, Boyang Zhang, Logan L Engle, Daphne Wang, Elizabeth Will, Joel C Sunshine, Daniel Jimenez-Sanchez, Zhen Zheng, Justina X Caushi, Jiajia Zhang, Nina D’Amiano, Julie Stein-Deutsch, Sonali Uttam, Katie Pirie, Darah Vlaminck, Michelle Mataj, Alexa Fiorante, Nicole Espinosa, Teodora Popa, […]


Continue.. Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS)