Kavli Affiliate: Peter Walter | Authors: Chari M Noddings, Rukmini Mukherjee, Carsten Peukert, Thomas G Laughlin, Jing Wang, Benjamin T Walters, Tsan-Wen Lu, Tristan Croll, Deniz Eismann, Shelly Harel, Angela Xu, Kibeom Kim, Meghna Gupta, James Crawford, Christopher P Arthur, Daniel Itzhak, Mauro Costa-Mattioli, Joachim Rudolph, Avi Ashkenazi and Peter Walter | Summary: The endoplasmic […]
Kavli Affiliate: Jin Kang | Authors: Kang Jin, Reuben A. Saunders, Jiahao Zhang, Jiaqi Lu, Aaron A. Halpern, Jaspreet Sandhu, Xingjie Pan, Cosmos Yuqi Wang, Alexander M. Li, William E. Allen, Jonathan S. Weissman and Xiaowei Zhuang | Summary: Genetic perturbations can reshape both the state of a targeted cell and the behavior of neighboring […]
Kavli Affiliate: David Kleinfeld | Authors: Jia-Jin Liu, Hidenobu Mizuno, Emmanuel Than-Trong, Philipp Machler, Hideaki Kubotera, Tony Barbay, Ching-Yao Wang, Qin-Ling To, Yuki Kamijo, Taki Nishimura, Marc Boisvert, Marie-Eve Paquet, Mikhail Drobizhev, Stephanie J Cragg, Jun Nagai, David Kleinfeld, Serge Charpak and Yusuke NASU | Summary: Extracellular L-lactate reports cellular metabolism, but resolving its dynamics […]
Kavli Affiliate: Menno Witter | Authors: Daniel Reznik, Cheslie C. Klein, Shir Filo, Menno P. Witter and Charlotte Grosse Wiesmann | Summary: Episodic memory critically depends on the hippocampus and the entorhinal cortex. Despite a rapid developmental change in human episodic memory during the first two years of life, little is known about the developmental […]
Kavli Affiliate: Rafael Yuste | Authors: Justin Lines and Rafael Yuste | Summary: During sleep onset (i.e. hypnagogia), visual hallucinations can occur in healthy human subjects following prolonged sensory experience. These percepts at sleep onset also occur in amnesiac patients and have signatures in human scalp electroencephalography recordings, suggesting a cortical origin. At the cellular […]
Kavli Affiliate: Li Zhao | Authors: Zhao Li, Aaron James and Shengxuan Li | Summary: Ambient RNA contamination confounds expression analysis in droplet-based single-cell and single-nucleus RNA sequencing. Here we present AmbiDose, which combines an ambient profile estimated from empty droplets with cell-specific nominal removal budgets and expression-based protection of lineage-enriched genes. Its ambient dose […]
Kavli Affiliate: Michael Miller | Authors: MoTrPAC Study Group, Anna R Brandt, Jerome Fleg, Bret H Goodpaster, Byron Jaeger, Christopher A Jin, Neil M Johannsen, Dan Katz, Hasmik Keshishian, Wendy M Kohrt, William E Kraus, Bridget Lester, Edward L Melanson, Michael E Miller, Samuel Montalvo, W Jack Rejeski, Samiya M Shimly, Gregory R Smith, Cynthia […]
Kavli Affiliate: Ekaterina V. Vinogradova | Authors: Tiffany L. Zhang, Henry Sanford, Railia R. Gabbasova, Anne E. van Vlimmeren, Yannis Kalaidzidis, Hiroyuki Kojima, Charlotte R Wayne, Jeetayu Biswas, Priyam Banerjee, Beatrice Zhang, Omar Abdel-Wahab, Marino Zerial and Ekaterina V Vinogradova | Summary: Macrophages are central regulators of innate immunity, yet the post-translational mechanisms that enable […]
Kavli Affiliate: Zachary Knight | Authors: Zhengya Liu, Ho Namkung, Jingkun Zhang, Julianne Davis, Naymalis La Santa Medina, Sophia Laskaris, Anyu Cao, Tianyi Chen, Xinlan Wen and Zachary A Knight | Summary: Drinking quenches thirst long before the ingested water has been absorbed. Here we investigate the mechanism by combining sham drinking, which uncouples water […]
Kavli Affiliate: Michael Miller | Authors: MoTrPAC Study Group, Daniel H. Katz, Christopher A. Jin, Gina M. Many, Gregory R. Smith, Hasmik Keshishian, Natalie M. Clark, Gayatri Iyer, Cheehoon Ahn, Malene E. Lindholm, Tyler J. Sagendorf, David Amar, Jacob L. Barber, Anna R. Brandt, Paul M. Coen, Yongchao Ge, Patrick Hart, Fang-Chi Hsu, Byron C. […]