Neuroscience – Page 2 – Kavli Institute Pre-Print Publications

Calcium-independent biosensors for multiplexed in vivo imaging of extracellular lactate dynamics

Posted by dbos October 5, 2026October 12, 2026UCSD / Salk

Kavli Affiliate: David Kleinfeld | Authors: Jia-Jin Liu, Hidenobu Mizuno, Emmanuel Than-Trong, Philipp Machler, Hideaki Kubotera, Tony Barbay, Ching-Yao Wang, Qin-Ling To, Yuki Kamijo, Taki Nishimura, Marc Boisvert, Marie-Eve Paquet, Mikhail Drobizhev, Stephanie J Cragg, Jun Nagai, David Kleinfeld, Serge Charpak and Yusuke NASU | Summary: Extracellular L-lactate reports cellular metabolism, but resolving its dynamics […]

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Distinct cortical networks associated with subregions of the hippocampal-entorhinal system in the first two years of human life

Posted by dbos October 2, 2026October 12, 2026NTNU

Kavli Affiliate: Menno Witter | Authors: Daniel Reznik, Cheslie C. Klein, Shir Filo, Menno P. Witter and Charlotte Grosse Wiesmann | Summary: Episodic memory critically depends on the hippocampus and the entorhinal cortex. Despite a rapid developmental change in human episodic memory during the first two years of life, little is known about the developmental […]

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Neuronal ensembles in visual cortex reactivate during hypnagogic sleep onset

Posted by dbos October 2, 2026October 12, 2026Columbia

Kavli Affiliate: Rafael Yuste | Authors: Justin Lines and Rafael Yuste | Summary: During sleep onset (i.e. hypnagogia), visual hallucinations can occur in healthy human subjects following prolonged sensory experience. These percepts at sleep onset also occur in amnesiac patients and have signatures in human scalp electroencephalography recordings, suggesting a cortical origin. At the cellular […]

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AmbiDose: per-cell removal budgets for ambient RNA contamination

Posted by dbos October 2, 2026October 12, 2026Rockefeller

Kavli Affiliate: Li Zhao | Authors: Zhao Li, Aaron James and Shengxuan Li | Summary: Ambient RNA contamination confounds expression analysis in droplet-based single-cell and single-nucleus RNA sequencing. Here we present AmbiDose, which combines an ambient profile estimated from empty droplets with cell-specific nominal removal budgets and expression-based protection of lineage-enriched genes. Its ambient dose […]

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Molecular Transducers of Physical Activity Consortium (MoTrPAC): Initial Insights into the Dynamic Human Responses to Exercise

Posted by dbos October 1, 2026October 12, 2026Hopkins

Kavli Affiliate: Michael Miller | Authors: MoTrPAC Study Group, Anna R Brandt, Jerome Fleg, Bret H Goodpaster, Byron Jaeger, Christopher A Jin, Neil M Johannsen, Dan Katz, Hasmik Keshishian, Wendy M Kohrt, William E Kraus, Bridget Lester, Edward L Melanson, Michael E Miller, Samuel Montalvo, W Jack Rejeski, Samiya M Shimly, Gregory R Smith, Cynthia […]

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Chemical proteomics reveals post-translational remodeling of endosomal pathways during macrophage activation.

Posted by dbos October 1, 2026October 12, 2026Rockefeller

Kavli Affiliate: Ekaterina V. Vinogradova | Authors: Tiffany L. Zhang, Henry Sanford, Railia R. Gabbasova, Anne E. van Vlimmeren, Yannis Kalaidzidis, Hiroyuki Kojima, Charlotte R Wayne, Jeetayu Biswas, Priyam Banerjee, Beatrice Zhang, Omar Abdel-Wahab, Marino Zerial and Ekaterina V Vinogradova | Summary: Macrophages are central regulators of innate immunity, yet the post-translational mechanisms that enable […]

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A learned oral signal drives long-lasting thirst satiation

Posted by dbos October 1, 2026October 12, 2026UCSF

Kavli Affiliate: Zachary Knight | Authors: Zhengya Liu, Ho Namkung, Jingkun Zhang, Julianne Davis, Naymalis La Santa Medina, Sophia Laskaris, Anyu Cao, Tianyi Chen, Xinlan Wen and Zachary A Knight | Summary: Drinking quenches thirst long before the ingested water has been absorbed. Here we investigate the mechanism by combining sham drinking, which uncouples water […]

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Multi-Omic, Multi-Tissue Responses to Acute Exercise in Sedentary Adults: Findings from the Molecular Transducers of Physical Activity Consortium

Posted by dbos September 30, 2026October 12, 2026Hopkins

Kavli Affiliate: Michael Miller | Authors: MoTrPAC Study Group, Daniel H. Katz, Christopher A. Jin, Gina M. Many, Gregory R. Smith, Hasmik Keshishian, Natalie M. Clark, Gayatri Iyer, Cheehoon Ahn, Malene E. Lindholm, Tyler J. Sagendorf, David Amar, Jacob L. Barber, Anna R. Brandt, Paul M. Coen, Yongchao Ge, Patrick Hart, Fang-Chi Hsu, Byron C. […]

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Hypoxia Disrupts Multiple Processes Supporting Spatial Navigation

Posted by dbos September 30, 2026October 12, 2026Rockefeller

Kavli Affiliate: Michael W. Young | Authors: Daniel J McKeown, Heiki M Bahnson-Wright, Trinity Caldwell, Madeliene Marks, Georgia R Marshall, Holly Newton, Dylan Stenholm, Michael Young, Douglas J Angus and Victor R Schinazi | Summary: Hypoxia impairs cognitive function, yet its effects on navigation and intrinsic brain activity remain poorly understood. This study investigated whether […]

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Adversity severity shapes caregiving predictors and neural correlates of infant social behavior

Posted by dbos September 30, 2026October 12, 2026Hopkins

Kavli Affiliate: Maya Opendak | Authors: Allison Su, Elaina Regier, Chloe Lim, Isaac McKie, Ben Perez-Flesler, Vishal Win, Isabellah Nikitah, Damaris Chacon, Brianna C. Bullock, Lucy Sparks Mendez, Keita Fogus, Kellie L.K. Tamashiro, Patrese A. Robinson and Maya Opendak | Summary: Early-life adversity is associated with highly variable developmental outcomes, but identifying sources of this […]

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