Neuroscience – Page 2 – Kavli Institute Pre-Print Publications

Psilocybin selectively rescues cognitive flexibility impairments caused by aberrant prefrontal error signalin

Posted by dbos July 9, 2026July 20, 2026UCSF

Kavli Affiliate: Vikaas Sohal | Authors: Christine Liu, Ellie M Ho, Alexander S Enos, Urte Beatrice Baublyte, Isabel M Luna, Alexander R Kosche and Vikaas S Sohal | Summary: Psychedelic drugs show remarkable potential for treating psychiatric disorders, but the mechanisms underlying their therapeutic effects remain relatively unknown. Here, we demonstrate that psilocybin can powerfully […]

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Conserved and specialized features of thalamocortical wiring revealed by single-cell projection mapping in mouse and marmoset

Posted by dbos July 9, 2026July 20, 2026Hopkins

Kavli Affiliate: Justus M Kebschull | Authors: Angela Y Fan, Jack T Scott, Noah M Kuehn, Maryam Majeed, Sabrina Y Cheng, Huihui Qi, Mathew T Summers, John Hover, Tye Johnson, Ben Ouellette, Alana A Oyama, Diana Ravens, Huiqing Zhan, Justus M Kebschull, James A Bourne and Xiaoyin Chen | Summary: Across mammals, brain regions can […]

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Age-related reorganization of locus coeruleus–cortical functional connectivity gradients

Posted by dbos July 8, 2026July 20, 2026NTNU

Kavli Affiliate: Maryam Ziaei | Authors: Arjun Dave, Shuer Ye, Xiaqing Lan, Alireza Salami, Heidi Jacobs and Maryam Ziaei | Summary: The locus coeruleus (LC) regulates attention, arousal, and adaptive behavior via widespread noradrenergic projections to cortex, yet its large-scale cortical organization and age-related vulnerability remain poorly understood. Using 7T MRI during naturalistic movie-viewing with […]

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Opposing GIPR brainstem circuits differentially control feeding behaviour

Posted by dbos July 8, 2026July 20, 2026UCSF

Kavli Affiliate: Zachary Knight | Authors: Natalie S Figueredo Burgos, Alejandro Lopez-Cruz, Cecilia Skoug, Anna G Roberts, Kathryn Xie, Iona Davies, Norio Harada, Nobuya Inagaki, Frank Reimann, Fiona M Gribble, Ben Jones, Daniel I Brierley, Stefan Trapp, Zachary A Knight and Alice E Adriaenssens | Summary: Central glucose-dependent insulinotropic polypeptide receptor (GIPR) signalling is required […]

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Decoupling Choice from Motor Response Reduces Choice-History Effects

Posted by dbos July 8, 2026July 20, 2026Columbia

Kavli Affiliate: Michael Shadlen | Authors: Sriram Thothathri, Bharath Chandra Talluri, S. Shushruth, Michael N. Shadlen and Hendrikje Nienborg | Summary: Perception and action form a loop as an organism interacts with its environment. Here, we probe the interdependence between the two in the context of choice-history effects, the tendency of past choices and their […]

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Rare sex punctuates strict asexual reproduction in the clonal raider ant, Ooceraea biroi

Posted by dbos July 8, 2026July 13, 2026Rockefeller

Kavli Affiliate: Daniel Kronauer | Authors: Kip D Lacy, Nicolas Châline and Daniel J.C. Kronauer | Summary: While asexual species can often outcompete their sexual counterparts over ecological timescales, their long-term evolutionary success is hindered by a diminished ability to purge deleterious mutations and to adapt to changing environments. However, some asexual species persist for […]

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Functional Organization of the Neonatal Basal Ganglia and Thalamus

Posted by dbos July 8, 2026July 13, 2026UCSD / Salk

Kavli Affiliate: Deanna J. Greene | Authors: Samantha Lynn Blake, Jeanette K. Kenley, Tara A. Smyser, Aidan Latham, Dimitrios Alexopoulos, Deanna J. Greene, Rachel E. Lean, Deanna M. Barch, Barbara B. Warner, Joan L. Luby, Cynthia E. Rogers, Christopher D. Smyser, Chad M. Sylvester and Ashley N. Nielsen | Summary: The basal ganglia and thalamus […]

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Semaphorin 3A promotes resilience of sleep and cognition to brain injury

Posted by dbos July 7, 2026July 13, 2026UCSF

Kavli Affiliate: Jeanne Paz | Authors: Deanna Necula, Yuliya Voskobiynyk, Srujana Poluri and Jeanne T. Paz | Summary: Chronic sleep disruption and cognitive deficits are debilitating long-term consequences of traumatic brain injury (TBI), yet the endogenous mechanisms that drive network-level recovery remain poorly understood. Here, we demonstrate that during the chronic phase post-injury, network oscillations […]

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Changes in perceptual sampling contribute to representational drift

Posted by dbos July 7, 2026July 13, 2026UCSD / Salk

Kavli Affiliate: John Serences | Authors: Yixin Yuan, John Serences and Mikio Christian Aoi | Summary: Gradual changes in neural response patterns to the same stimulus over time, termed representational drift, have been widely observed across cortical areas. Drift is typically attributed to intrinsic neural dynamics driven by synaptic plasticity or turnover. Here we test […]

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The emergence of a novel CA1 spatial map requires direct entorhinal input

Posted by dbos July 7, 2026July 20, 2026NTNU

Kavli Affiliate: Clifford Kentros | Authors: Oscar M. T. Chadney, Matteo Guardamagna, Felix Dorr, Lucie A. L. Descamps, Federico Stella, Francesco Battaglia and Clifford G. Kentros | Summary: The hippocampus and its main input, the entorhinal cortex, are essential for memory formation, yet how they interact to do so remains unresolved. Hippocampal CA1 pyramidal neurons […]

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