Kavli Affiliate: Daniel Kronauer | Authors: Kip D Lacy, Nicolas Châline and Daniel J.C. Kronauer | Summary: While asexual species can often outcompete their sexual counterparts over ecological timescales, their long-term evolutionary success is hindered by a diminished ability to purge deleterious mutations and to adapt to changing environments. However, some asexual species persist for […]
Kavli Affiliate: Daniel Mucida | Authors: Marwa Saad, Alexandra Thoms, Yue S. Yin, Izabela Mamede, Afsana Rahman, Ruonan Chen, Sebastian E. Carrasco, Patrick W. Darcy, Norihiro Goto, Sohail F. Tavazoie, Angelina M. Bilate and Daniel Mucida | Summary: Colorectal cancer (CRC) remains a leading cause of cancer mortality, with most cases refractory to immunotherapy. Distinguishing […]
Kavli Affiliate: Erich Jarvis | Authors: Jonathan Fenn, Jessica C Edge, Vladimir Ovchinnikov, Olga Amelkina, Melea Sinclair, Tiago H C De Bem, Alessandra Bridi, Irene Malo-Estepa, Angela Gonella-Diaza, Felipe Perecin, Juliano C da Silveira, Guilherme Pugliesi, Flavio Vieira Meirelles, Zenab Butt, Haidee Tinning, Giulio Formenti, Erich Jarvis, Bastian Fromm, James O McInerney, Niamh Forde and […]
Kavli Affiliate: Erich Jarvis | Authors: Giulio Formenti, Dominic E. Absolon, Linelle Ann L. Abueg, Francine Ackerman, Farooq Omar Al-Ajli, Alexandre Aleixo, Agostinho Antunes, Dahiana Arcila, Jean-Nicolas Audet, Jennifer R. Balacco, Alan James Stephen Beavan, Katherine Belov, Ricardo Betancur-R., Shelby L Bidwell, Matthew T Biegler, Iliana Bista, Mark Blaxter, Kevin Boyer, Ingo Braasch, Ian R […]
Kavli Affiliate: Li Zhao | Authors: Zhao Li, Jian Chen, Emily M Cross, Megan A Outram, Daniel S Yu, Jana Sperschneider, Melania Figueroa, Peter N Dodds and Simon J Williams | Summary: Interactions between plants and pathogens drive long-term co-evolution through cycles of effector diversification and immune recognition. Effectors play central roles in this molecular […]
Kavli Affiliate: Li Zhao | Authors: Megan Outram, Zhao Li, Michael Kuiper, Simon J Williams, Melania Figueroa, Peter Dodds and Jana Sperschneider | Summary: Rust fungi are significant threats to global food security, causing substantial damage to crops through their ability to adapt and evolve new strains that overcome resistance. These obligate biotrophs infect host […]
Kavli Affiliate: Leslie B. Vosshall | Authors: Umberto Palatini, Stéphanie Dabo, Adriana Rosas-Villegas, Yael N. Tsitohay, Alexandra E. DeFoe, Nadav Shai, Louis Lambrechts and Leslie B. Vosshall | Summary: Billions of people each year are at risk from infection by dengue, Zika, yellow fever, and chikungunya viruses, which are transmitted by female Aedes aegypti mosquitoes. […]
Kavli Affiliate: Daniel Mucida | Authors: Patrick W Darcy, Vitoria M Olyntho, Albana Kodra, Zachary Kerner, Maria C.C. Canesso, Sandra Nakandakari-Higa, Gabriel Victora and Daniel Mucida | Summary: Food allergies are associated with progressive gastrointestinal symptoms driven by exacerbated mucosal type-2 immunity. Here, we investigated whether cellular interactions between the gut epithelium and innate immune […]
Kavli Affiliate: Charles M. Rice | Authors: Trinity Zang, Viren A Baharani, Miranda Aldis, Marie Canis, Rachel Patejak, Edmund Osei Kuffour, Hans Heinrich Hoffman, Harm van Bakel, Emilia M Sordillo, Viviana Simon, Margaret R MacDonald, Charles M Rice, Michel C Nussenzweig, Theodora Haziionannou and Paul D Bieniasz | Summary: A central problem in achieving vaccine-based […]
Kavli Affiliate: Winrich Freiwald and Alipasha Vaziri | Authors: Santiago Otero-Coronel, David Grant Colburn Hildebrand, Tobias Noebauer, Jeffrey Demas, Brandon Chen, Siegfried Weisenburger, Frank Tejera, Sverre Grodem, Kristian Kinden Lensjo, Guro Helen Vatne, Marianne Fyhn, Winrich A Freiwald and Alipasha Vaziri | Summary: Primate neocortex is organized into functionally defined domains. Understanding how the functional […]