Kavli Affiliate: Flora Vaccarino | Authors: Taejeong Bae, Livia Tomasini, Leszek J. Klimczak, Merit Kayastha, Milovan Suvakov, Yeongjun Jang, Alexandre Jourdon, Dmitry A. Gordenin, Flora M. Vaccarino and Alexej Abyzov | Summary: Somatic mutations that arise post-zygotically create genetic diversity among normal human cells and provide key insights into human development and aging. Fibroblast-derived induced […]

Kavli Affiliate: Ellen J. Hoffman | Authors: Wei Qin, Jessica Beevis, Maya Wilde, Sarah Stednitz, Joshua Arnold, Manxiu Ma, Itia A. Favre-Bulle, Andre Peterson, Ellen J Hoffman and Ethan Scott | Summary: Despite its prevalence and clinical impacts, epilepsy remains incompletely understood in terms of the population dynamics that mediate seizure susceptibility, initiation, and propagation […]

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Stephen Strittmatter | Authors: Francesca Mandino, Xilin Shen, Corey Horien, Xenophon Papademetris, Stephen M. Strittmatter, Shella D Keilholz, Nan Xu and Evelyn MR Lake | Summary: Functional magnetic resonance imaging (fMRI) captures whole-brain activity fluctuations non-invasively in humans and animals. […]

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Shawn Ferguson | Authors: John Michael Replogle, Jordan D Marks, Martin G Fernandez, Hebao Yuan, Belle Yu, Elizabeth Winters, Vidhya Maheswari Jawahar, Rishi Deshmukh, Renaldo Sutanto, Isabelle Kowal, Ashley Frankenfield, Rachel Shi, Yari Carlomagno, Karen Jansen-West, Tiffany Todd, Andrii Kopach, […]

Kavli Affiliate: Stephen Strittmatter | Authors: Francesca Mandino, Xilin Shen, Corey Horien, Xenophon Papademetris, Stephen M. Strittmatter, Shella Keilholz, Nan Xu and Evelyn MR Lake | Summary: Functional magnetic resonance imaging (fMRI) captures whole-brain activity fluctuations non-invasively in humans and animals. Beyond task/stimuli-locked responses, fMRI measures large-scale patterned activity during rest. An established method for […]

Kavli Affiliate: Pietro De Camilli | Authors: Devin M Fuller, Yumei Wu, Florian Schueder, Burha Rasool, Shanta Nag, Justin L. Korfhage, Rolando Garcia-Milian, Katerina D Melnyk, Joerg Bewersdorf, Pietro De Camilli and Thomas Melia | Summary: Autophagosomes form from seed membranes that expand through bulk-lipid transport via the bridge-like lipid transporter ATG2. The origins of […]

Kavli Affiliate: Anirvan Nandy | Authors: Weikang Shi, Olivia C. Meisner, Monika P. Jadi, Steve W. C. Chang and Anirvan S. Nandy | Summary: Successful cooperation requires dynamic integration of social cues. However, the neural mechanisms supporting this complex process remain unknown. Here, we reveal that the primate dorsomedial prefrontal cortex (dmPFC) implements a gaze-dependent […]

Kavli Affiliate: Elena Gracheva | Authors: Shahira Helal Arzoo, Chase Drucker, Rubaia Tasmin, Nicolas Jones, Elena Gracheva, Abigail Matt, Raymond Hsin, Fei Wang, Chao Zhou and Surya Banerjee | Summary: The knock-out mutation of the unique M13 family member, the Drosophila melanogaster (fruit fly) Neprilysin-like 15 (Nepl15), resulted in marked reductions of glycogen and glycerolipid […]

Kavli Affiliate: Marina Picciotto | Authors: WenLiang Zhou, Hanna Yousuf, Yann S Mineur and Marina Picciotto | Summary: Activity of the mesolimbic system is essential for adaptive performance of reward-related behaviors. Within this system, dopaminergic (DAergic) neurons play a critical role in driving motivation to obtain rewards and encoding predictions and error signals during reinforcement […]

Kavli Affiliate: Ellen J. Hoffman | Authors: April Pruitt, Liang Yang, Seoyeon Lee, Novin Balafkan, Carina Seah, Yi Dai, Elizabeth Davidson, Suha Khan, Annabel Sen, Jenny Liu, Isabel Wood, Gang Xu, Xiayuan Huang, Marina Carlson, Dejian Zhao, Priyanka Jamadagni, Grace Dossou, Kayla Retallick-Townsley, Xinyun Liu, P.J. Michael Deans, Meilin Fernandez Garcia, Huanyao Gao, Zuoheng Wang […]