Kavli Affiliate: Terrence Sejnowski | Authors: Matthew Hur, Thomas Bartol, Padmini Rangamani, Terrence Sejnowski and Eric Mjolsness | Summary: There is a morphodynamic component to synaptic learning by which changes in dendritic (postsynaptic) spine head size are associated with the strengthening or weakening of the synaptic connection between two neurons, in response to the temporal […]
Kavli Affiliate: Wesley Thompson | Authors: Lucy Shao, Kilian M. Pohl and Wesley K. Thompson | Summary: The Synthetic Control Method (SCM) and its interactive factor model generalizations (GSC) are powerful for estimating causal effects from panel data but are not easily applied when follow-up is irregular or sparse, common features of biomedical cohorts. We […]
Kavli Affiliate: Dhakshin Ramanathan and Jyoti Mishra | Authors: Jonathan H Mishler, Morteza Salimi, Miranda Francoeur Koloski, Irene Rembado, Carrie Shilyansky, Jyoti Mishra and Dhakshin Ramanathan | Summary: Neural oscillations are widely used as proxies for neuronal activity, where power in individual frequency bands is commonly interpreted as functionally indexing neural circuit engagement. However, power […]
Kavli Affiliate: Kenta Asahina | Authors: Donovan Ventimiglia, Elizabeth Chamiec-Case, Claire S Lee, Bruce Ruff and Kenta Asahina | Summary: Social conflict is a fundamental challenge for all animals and determines access to critical resources like mates and food. Evolutionary game theory predicts that natural selection should yield competitive strategies that balance the benefits and […]
Kavli Affiliate: Ann-Shyn Chiang | Authors: Pin-Hsun Lian, Tzu-Yi Chuang, Ya-Ding Liu, Li-An Chu, Sheng-Cheng Chang, Yu-Chen Kuo, Wei-Kun Chang, Ann-Shyn Chiang and Gary Chang | Summary: Expansion microscopy (ExM) enables nanoscale imaging for disease characterization. However, whole-organ analyses remain limited by several challenges. Current super-resolution methods either require high-resolution ground-truth data or assume spatially […]
Kavli Affiliate: Terrence Sejnowski | Authors: Margot Wagner, Yusi Chen, Arjun Karuvally, Mia Cameron and Terrence J Sejnowski | Summary: sequential dynamics underlying replay, prediction and traveling waves. How hippocampal circuitry achieves both remains unclear. Here, we show that recurrent neural networks trained on continuous prediction tasks converge to a mixed-symmetry dynamical regime, in which […]
Kavli Affiliate: Kenta Asahina | Authors: Lesly M Palacios Castillo, Valentina Fajner, Ezgi Yalbir, Shafana Shahul, Bruce Ruff, Victor Junmyung Lee, Aundrea Koger, Juliet Heller, Kenichi Ishii, Veronica Morad, Max Trask, Carter Warren, Giovanni Frighetto, Mark A Frye and Kenta Asahina | Summary: Octopamine (OA) is a major biogenic amine in the invertebrate nervous system […]
Kavli Affiliate: Cory Miller | Authors: Jingwen Li, Vikram Pal Singh, Jude F. Mitchell, Alexander C. Huk and Cory T. Miller | Summary: Human and nonhuman primates rely heavily on vision to actively explore and navigate their environment. Although primate visual cortex has been studied extensively in head-fixed animals, little is known about how the […]
Kavli Affiliate: Wesley Thompson | Authors: Michael Rosario, Carlos Cardenas-Iniguez, Jennifer V Chavez, Katherine L Bottenhorn, Hedyeh Ahmadi, Megan M Herting and Wesley K Thompson | Summary: Background Enriched environments support neurodevelopment. The pathways linking enrichment to cognitive processes such as episodic memory among youth remain unclear. This study examined whether brain function and structure […]
Kavli Affiliate: Sreekanth Chalasani | Authors: Lei Zhang, Jing Zhang, Tsui-Min Wang, Callum Walsh, Farah Sheikh, Sreekanth H. Chalasani and James Friend | Summary: Electronic cardiac pacemakers are the standard of care for treating arrhythmias but, even for wireless pacemakers, they require an intracardiac implant procedure and are invasive. Lead-related complications, including life-threatening infections, and […]