UCSD / Salk – Kavli Institute Pre-Print Publications

Purification and characterization of recombinant Rtt109, a fungus-specific histone acetyltransferase, from Candida albicans

Posted by dbos July 30, 2026August 5, 2026This Week: Neuroscience, UCSD / Salk

Kavli Affiliate: V. S. Ramachandran | Authors: Simran Sharma, Vijayan Ramachandran, Sneha Sudha Komath, Rohini Muthuswami and Samudrala Gourinath | Summary: Epigenetic regulation of chromatin dynamics via histone acetylation is one of several mechanisms by which eukaryotes regulate gene expression, DNA replication and repair, and maintain genome stability. This function is performed by histone […]

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Social isolation recruits amygdala-medial prefrontal cortex projections to escalate alcohol drinking in male mice

Posted by dbos July 27, 2026August 5, 2026This Week: Neuroscience, UCSD / Salk

Kavli Affiliate: Kay Tye | Authors: Reesha Patel, Kelly Kim, Makenzie Patarino, Rachelle Pamintuan, Felix Taschbach, Hao Li, Bitna Joo, Anna Pallé, Xianru Yu, Christopher R Lee, Aniek van Hoek, Jesse White, Rogelio Castro, Christian Cazares, Raymundo Miranda, Caroline Jia, Jeremy Delahanty, Kanha Batra, Laurel Keyes, Avraham Libster, Romy W. Wichmann, Talmo Pereira, Marcus […]

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iG6PSnFR: A genetically encoded fluorescent sensor for observing glucose-6-phosphate dynamics in living preparations

Posted by dbos July 23, 2026August 5, 2026This Week: Neuroscience, UCSD / Salk

Kavli Affiliate: Timothy Brown | Authors: Jonathan S. Marvin, Anastasia Tsives, Shih Ming Huang, Zhanat Koshenov, Raghabendra Adhikari, Aaron D. Wolfe, Ian J. Gonzalez, Daniel Feliciano, Timothy A. Ryan, Matthew J. Merrins, Daniel A. Colón-Ramos and Timothy A. Brown | Summary: Glucose-6-phosphate (G6P) is a key intermediate in multiple energetic and anabolic pathways, and […]

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Functional Organization of the Neonatal Basal Ganglia and Thalamus

Posted by dbos July 8, 2026July 13, 2026UCSD / Salk

Kavli Affiliate: Deanna J. Greene | Authors: Samantha Lynn Blake, Jeanette K. Kenley, Tara A. Smyser, Aidan Latham, Dimitrios Alexopoulos, Deanna J. Greene, Rachel E. Lean, Deanna M. Barch, Barbara B. Warner, Joan L. Luby, Cynthia E. Rogers, Christopher D. Smyser, Chad M. Sylvester and Ashley N. Nielsen | Summary: The basal ganglia and thalamus […]

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Changes in perceptual sampling contribute to representational drift

Posted by dbos July 7, 2026July 13, 2026UCSD / Salk

Kavli Affiliate: John Serences | Authors: Yixin Yuan, John Serences and Mikio Christian Aoi | Summary: Gradual changes in neural response patterns to the same stimulus over time, termed representational drift, have been widely observed across cortical areas. Drift is typically attributed to intrinsic neural dynamics driven by synaptic plasticity or turnover. Here we test […]

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Clinical Relevant Immunosuppressive Drugs Differentially Modulate Axonal Outgrowth from Human Stem Cell Derived Neurons

Posted by dbos July 2, 2026July 13, 2026UCSD / Salk

Kavli Affiliate: Mark H. Tuszynski | Authors: Gunnar H.D. Poplawski, Chase Weinholtz, Grace Woodruff, Ruhel Ahmad, Wyatt Bunner, Rodrigo Gonzales and Mark H. Tuszynski | Summary: Neural stem cell (NSC) transplantation is a promising strategy for repairing the injured spinal cord, but transplanted cells typically require immunosuppressive therapy to prevent rejection—even for induced pluripotent stem […]

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A 3D Brain Geometry Toolkit for Multisite Neuroimaging Analysis

Posted by dbos July 2, 2026July 13, 2026UCSD / Salk

Kavli Affiliate: Anders Dale | Authors: Yanghee Im, Melody J.Y. Kang, Boris A. Gutman, Pravesh Parekh, Diliana Pecheva, Anders M. Dale, Ole A. Andreassen, Paul M. Thompson, Christopher R.K. Ching and for the ENIGMA Bipolar Disorder Working Groupz | Summary: Compared to traditional gross volumetrics, surface-based models provide greater spatial precision for understanding brain alterations […]

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Resilience to neuronal hyperactivity and restoration of the neuroimmune interactome by blocking fibrin-induced microglia activation in Alzheimers disease

Posted by dbos June 26, 2026July 13, 2026UCSD / Salk

Kavli Affiliate: Mark Ellisman | Authors: Zhaoqi Yan, Andrew S Mendiola, Kelli Lauderdale, Keun-Young Kim, Yu Yong, Kun Leng, Eric A Bushong, Renaud Schuck, Anke Meyer-Franke, Ayushi Agrawal, Michela Traglia, Natalie Gill, Reuben Thomas, Jonah N Keller, Nikolaos Karvelas, Miguel F Vasquez, Daniel C Ballard, Matthew Madany, Jeffrey Simms, Brandon Guo, Reshmi Tognatta, Maria del […]

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The Role of Macronutrient Composition in Semipurified Diets in Shaping Distinct Obesity Phenotypes: Evidence for Hepatic Oxidative Stress Involvement

Posted by dbos June 26, 2026July 13, 2026UCSD / Salk

Kavli Affiliate: Gabriel Silva | Authors: Pedro Rocha Tenorio, Gabriel Smolak Sobieski e Silva, Isadora Chagas Vercellone, Débora Hipólito Quadreli, Juliany Carolina Duma de Castro, Glaura Scantamburlo Alves Fernandes and Fábio Goulart de Andrade | Summary: While obesity is widely recognized as a global epidemic, the specific roles of food processing and macronutrient composition in […]

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Long-term memory performance optimization via Neural network-based curve fitting in Drosophila

Posted by dbos June 25, 2026July 13, 2026UCSD / Salk

Kavli Affiliate: Ann-Shyn Chiang | Authors: Yung-Ching Lu, Chih-Ying Chen, Ling-Hui Yen, Chi-Lien Yang, Ya-Ding Liu, Wen-Jun Chen, Kuan-Lin Feng, Ming-Chin Wu, Ann-Shyn Chiang, Da-Jeng Yao, Chih-Ming Ho, Shih-Hwa Chiou and Li-An Chu | Summary: Long-term memory (LTM) formation typically requires extensive training or highly salient experiences, limiting learning efficiency. Operant conditioning is generally thought […]

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