Versatile Multiple Object Tracking in Sparse 2D/3D Videos Via Diffeomorphic Image Registration

Kavli Affiliate: Liam Paninski | Authors: James Yu, Amin Nejatbakhsh, Mahdi Torkashvand, Sahana Gangadharan, Maedeh Seyedolmohadesin, Jinmahn Kim, Liam Paninski and Vivek Venkatachalam | Summary: Tracking body parts in behaving animals, extracting fluorescence signals from cells embedded in deforming tissue, and analyzing cell migration patterns during development all require tracking objects with partially correlated motion. […]


Continue.. Versatile Multiple Object Tracking in Sparse 2D/3D Videos Via Diffeomorphic Image Registration

Distributional coding of associative learning within projection-defined populations of midbrain dopamine neurons

Kavli Affiliate: Costa, Rui | Authors: Riccardo Avvisati, Anna-Kristin Kaufmann, Callum J Young, Gabriella E Portlock, Sophie Cancemi, Rui Ponte Costa, Peter J Magill and Paul D Dodson | Summary: Midbrain dopamine neurons are thought to play key roles in learning by conveying the difference between expected and actual outcomes. While this teaching signal is […]


Continue.. Distributional coding of associative learning within projection-defined populations of midbrain dopamine neurons

Increased mutation rate and interlocus gene conversion within human segmental duplications.

Kavli Affiliate: Michael Goldberg | Authors: Mitchell R. Vollger, William S. DeWitt, Philip C. Dishuck, William T. Harvey, Xavi Guitart, Michael E. Goldberg, Allison Rozanski, Julian Lucas, Mobin Asri, The Human Pangenome Reference Consortium, Katherine M. Munson, Alexandra P. Lewis, Kendra Hoekzema, Glennis A. Logsdon, David Porubsky, Benedict Paten, Kelley Harris, PingHsun Hsieh and Evan […]


Continue.. Increased mutation rate and interlocus gene conversion within human segmental duplications.

Sub-harmonic Entrainment of Cortical Gamma Oscillations to Deep Brain Stimulation in Parkinson’s Disease: Predictions and Validation of a Patient-Specific Non-Linear Model

Kavli Affiliate: Philip Starr | Authors: James J. Sermon, Maria Olaru, Juan Anso, Simon Little, Rafal Bogacz, Philip A. Starr, Timothy Denison and Benoit Duchet | Summary: Objectives The exact mechanisms of deep brain stimulation (DBS) are still an active area of investigation, in spite of its clinical successes. This is due in part to […]


Continue.. Sub-harmonic Entrainment of Cortical Gamma Oscillations to Deep Brain Stimulation in Parkinson’s Disease: Predictions and Validation of a Patient-Specific Non-Linear Model

Uncertainty alters the balance between incremental learning and episodic memory

Kavli Affiliate: Daphna Shohamy | Authors: Jonathan Nicholas, Nathaniel Douglass Daw and Daphna Shohamy | Summary: A key question in decision making is how humans arbitrate between competing learning and memory systems to maximize reward. We address this question by probing the balance between the effects, on choice, of incremental trial-and-error learning versus episodic memories […]


Continue.. Uncertainty alters the balance between incremental learning and episodic memory

Rotating Frame Relaxation for Magic Angle Spinning Solid State NMR, A Promising Tool for Characterizing Biopolymer Motion

Kavli Affiliate: Ann McDermott | Authors: Ann E McDermott and Eric G Keeler | Summary: Magic angle spinning NMR rotating frame relaxation measurements provide a powerful experimental strategy to probe biomolecules dynamics, as is illustrated by numerous recent applications. We discuss experimental strategies for this class of experiments, with a particular focus on systems where […]


Continue.. Rotating Frame Relaxation for Magic Angle Spinning Solid State NMR, A Promising Tool for Characterizing Biopolymer Motion

Nuclear architecture protein Distal antenna balances genome-binding and phase-separation properties to regulate neuroblast competence

Kavli Affiliate: Minoree Kohwi | Authors: Gillie Benchorin, Maggie Jiaqi Li, Richard Jangwon Cho, Yuxin Hu and Minoree Kohwi | Summary: Neural progenitors transit through multiple competence states that restrict production of each neural cell type. In Drosophila neuroblasts, a timed genome reorganization relocates the cell fate gene, hunchback, to the nuclear periphery, terminating competence […]


Continue.. Nuclear architecture protein Distal antenna balances genome-binding and phase-separation properties to regulate neuroblast competence

High-resolution magic angle spinning NMR of KcsA in liposomes: the highly mobile C-terminus

Kavli Affiliate: Ann McDermott | Authors: Ann E McDermott and Gary Stanley Howarth II | Summary: The structure of the transmembrane domain of bacterial potassium channel KcsA has been extensively characterized, yet little information is available on the structure of its cytosolic N- and C-termini. This study presents high-resolution magic angle spinning (HR-MAS) and fractional […]


Continue.. High-resolution magic angle spinning NMR of KcsA in liposomes: the highly mobile C-terminus

Targeted cortical stimulation reveals principles of cortical contextual interactions

Kavli Affiliate: Kenneth Miller | Authors: Shen Wang, Agostina Palmigiano, Kenneth D Miller and Stephen David Van Hooser | Summary: Cross-orientation suppression is a classic form of contextual normalization in visual cortex, yet the degree to which cortical circuits participate in the normalization computation is unclear. We visualized orientation maps of individual ferrets, and provided […]


Continue.. Targeted cortical stimulation reveals principles of cortical contextual interactions

An Internal Model of Sensorimotor Context in Freely Swimming Electric Fish

Kavli Affiliate: Nathaniel Sawtell | Authors: Avner Wallach and Nathaniel B Sawtell | Summary: Nervous systems are hypothesized to learn and store internal models that predict the sensory consequences of motor actions. However, little is known about the neural mechanisms for generating accurate predictions under real-world conditions in which the sensory consequences of action depend […]


Continue.. An Internal Model of Sensorimotor Context in Freely Swimming Electric Fish