Neuroscience – Page 4 – Kavli Institute Pre-Print Publications

GPCRs as Targets for Human Brain Modulation: A Multi-omic Atlas of Cell-Type Specific Expression

Posted by klaurent March 24, 2026April 6, 2026Rockefeller

Kavli Affiliate: Nathaniel Heintz | Authors: Alan Umfress, Patrick Wertimer, Christina Pressl, Matthew Baffuto, Kert Mätlik, Franchesca Fernandez, Maria Esterlita Siantoputri, Ines Ibañez-Tallon and Nathaniel Heintz | Summary: G Protein coupled receptors (GPCRs) are the largest class of clinically validated drug targets with nearly 35% of all approved therapeutic agents acting on these receptors. To […]

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FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets

Posted by dbos March 24, 2026April 6, 2026UCSD / Salk

Kavli Affiliate: Anders Dale and Wesley Thompson | Authors: Pravesh Parekh, Nadine Parker, Diliana Pecheva, Evgeniia Frei, Marc Vaudel, Diana M. Smith, Alison Rigby, Piotr Jahołkowski, Ida Elken Sønderby, Viktoria Birkenæs, Nora Refsum Bakken, Chun Chieh Fan, Carolina Makowski, Jakub Kopal, Robert John Loughnan, Donald J. Hagler, Jr., Dennis van der Meer, Stefan Johansson, Pål […]

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Leveraging AI-powered interactive playbacks to decipher rules of communication in zebra finches

Posted by dbos March 23, 2026March 30, 2026Columbia

Kavli Affiliate: Sarah Woolley | Authors: Logan S James, Benjamin Hoffman, Jen-Yu Liu, Marius Miron, Milad Alizadeh, Emmanuel Fernandez, Matthieu Geist, Diane Kim, Aza Raskin, Jon T Sakata, Emmanuel Chemla, Olivier Pietquin and Sarah C Woolley | Summary: Vocal interactions are fundamental for social functioning across animals, including humans. The diverse rules underlying these exchanges […]

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NPAS4 refines spatial and temporal firing in CA1 pyramidal neurons

Posted by dbos March 22, 2026March 30, 2026UCSD / Salk

Kavli Affiliate: Jill Leutgeb | Authors: Anja Payne, Daniel A. Heinz, Chiaki Santiago, Lara L. Hagopian, Rolando Sceptre Ganasi, Clare Quirk, Andrea L. Hartzell, Jill K. Leutgeb, Stefan Leutgeb and Brenda L. Bloodgood | Summary: NPAS4 is an activity-dependent transcription factor that, in CA1 of the hippocampus, regulates inhibitory synapses made onto the active pyramidal […]

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Acceleration and Velocity Dissociate Temporal Phases of Postural Control in Rhesus Macaques

Posted by dbos March 21, 2026March 30, 2026Hopkins

Kavli Affiliate: Kathleen Cullen | Authors: Olivia M. E. Leavitt Brown, Bassil A Ramadan and Kathleen E Cullen | Summary: Maintaining balance requires the nervous system to transform sensory signals about unexpected postural perturbations into precisely timed motor commands. Although human studies have established that postural responses unfold in distinct temporal phases, how specific kinematic […]

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Multi-Omic, Multi-Tissue Responses to Acute Exercise in Sedentary Adults: Findings from the Molecular Transducers of Physical Activity Consortium

Posted by dbos March 20, 2026March 30, 2026Hopkins

Kavli Affiliate: Michael Miller | Authors: MoTrPAC Study Group, Daniel H. Katz, Christopher A. Jin, Gina M. Many, Gregory R. Smith, Hasmik Keshishian, Natalie M. Clark, Gayatri Iyer, Cheehoon Ahn, Malene E. Lindholm, Tyler J. Sagendorf, David Amar, Jacob L. Barber, Anna R. Brandt, Paul M. Coen, Yongchao Ge, Patrick Hart, Fang-Chi Hsu, Byron C. […]

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ATG2A interacts with RAB1A and ARFGAP1 positive membranes during autophagosome biogenesis

Posted by dbos March 19, 2026March 30, 2026Yale

Kavli Affiliate: Pietro De Camilli | Authors: Devin M Fuller, Yumei Wu, Florian Schueder, Burha Rasool, Shanta Nag, Justin L. Korfhage, Rolando Garcia-Milian, Katerina D Melnyk, Joerg Bewersdorf, Pietro De Camilli and Thomas Melia | Summary: Autophagosomes form from seed membranes that expand through bulk-lipid transport via the bridge-like lipid transporter ATG2. The origins of […]

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Single-library chromosome-scale diploid assemblies of vole genomes resolve a species-specific duplication implicated in pair bonding

Posted by dbos March 17, 2026March 30, 2026UCSF

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Devanand Manoli | Authors: Mohamed Abuelanin, Gulhan Kaya, Juniper A Lake, Christine Lambert, Melody V Wu, Kristen Berendzen, Ksenia Krasheninnikova, Jonathan MD Wood, Nancy G Solomon, Zoe R Donaldson, Karen L Bales, Kerstin Howe, Jonas Korlach, Devanand S Manoli, Jessica […]

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Rapid and repeated evolution of myosin copy number in threespine stickleback

Posted by dbos March 17, 2026March 30, 2026UCSF

Kavli Affiliate: Alex Pollen | Authors: Alyssa M Yoxsimer, Rhea R Daugherty, Emily E Hare, Yingguang Frank Chan, Felicity C Jones, Garrett A Roberts Kingman, Emma G Offenberg, Timothy R Howes, Haili Zhang, Alex Aaron Pollen, Shannon D Brady, Kathleen T Xie, Heidi I Chen, Craig B Lowe, Eric H Au, Jane Grimwood, Jeremy Schmutz, […]

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Precision targeting of autoreactive B cells in systemic lupus erythematosus using anti-9G4 idiotope synthetic immune receptor T cells

Posted by dbos March 17, 2026March 30, 2026Hopkins

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Denis Wirtz | Authors: Jin Liu, Yuanxuan Xia, Brian Mog, Colin Gliech, Elana Shaw, Dylan Ferris, Brock Moritz, Tolulope Awosika, Sarah DiNapoli, Stephanie Glavaris, Kyle J Kaeo, Yang Li, Nikita Marcou, Alexander H Pearlman, Taha Ahmedna, Regina Bugrovsky, Ignacio Sanz, […]

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