November 2022 – Page 7 – Kavli Institute Pre-Print Publications

Direct Cortical Inputs to Hippocampal Area CA1 Transmit Complementary Signals for Goal-directed Navigation

Posted by klaurent November 13, 2022December 19, 2022Columbia

Kavli Affiliate: Attila Losonczy | Authors: John C Bowler and Attila Losonczy | Summary: Summary The entorhinal cortex (EC) is central to the brain’s navigation system. Its subregions are conventionally thought to compute dichotomous representations for spatial processing: medial entorhinal cortex (MEC) provides a global spatial map, while lateral entorhinal cortex (LEC) encodes specific sensory […]

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The HCN1 hyperpolarization-activated cyclic nucleotide-gated channel enhances evoked GABA release from parvalbumin positive interneurons

Posted by klaurent November 13, 2022November 21, 2022Columbia

Kavli Affiliate: Steven Siegelbaum | Authors: Tobias Bock, Eric W Buss, Olivia M Lofaro, Felix W Leroy, Bina Santoro and Steven A Siegelbaum | Summary: Abstract Hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels generate the cationic Ih current in neurons and regulate the excitability of neuronal networks. The function of HCN channels depends, in part, on their […]

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Converting an allocentric goal into an egocentric steering signal

Posted by klaurent November 13, 2022November 21, 2022Rockefeller

Kavli Affiliate: Gaby Maimon | Authors: Peter Mussells Pires, L F Abbott and Gaby Maimon | Summary: Abstract Neuronal signals relevant for spatial navigation have been described in many species[1-12], however, a circuit-level understanding of how such signals interact to guide behaviour is lacking. Here we characterize a neuronal circuit in the Drosophila central complex […]

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Electrostatic control of the proximity effect in the bulk of semiconductor-superconductor hybrids

Posted by dbos November 12, 2022Delft

Kavli Affiliate: L. P. Kouwenhoven | First 5 Authors: N. van Loo, G. P. Mazur, T. Dvir, G. Wang, R. C. Dekker | Summary: The proximity effect in semiconductor-superconductor nanowires is expected to generate an induced gap in the semiconductor. The magnitude of this induced gap, together with the semiconductor properties like the spin-orbit coupling […]

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Electrostatic control of the proximity effect in the bulk of semiconductor-superconductor hybrids

Posted by dbos November 12, 2022Delft

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Tautomer-specific deacylation and Ω-loop flexibility explain carbapenem-hydrolyzing, broad-spectrum activity of the KPC-2 β-lactamase

Posted by klaurent Hopkins

Kavli Affiliate: Michael Beer | Authors: Catherine L Tooke, Philip Hinchliffe, Michael Beer, Kirill Zinovjev, Charlie K Colenso, Christopher J Schofield, Adrian J Mulholland and James Spencer | Summary: Abstract KPC-2 (Klebsiella pneumoniae carbapenemase-2) is a globally disseminated serine-β-lactamase (SBL) responsible for extensive β-lactam antibiotic resistance in Gram-negative pathogens. SBLs inactivate β-lactams via a mechanism […]

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Inflammation-Responsive Micellar Nanoparticles from Degradable Polyphosphoramidates for Targeted Delivery to Myocardial Infarction

Posted by klaurent November 11, 2022November 21, 2022UCSD / Salk

Kavli Affiliate: Karen Christman | Authors: Yifei Liang, Holly Sullivan, Kendal Carrow, Joanna Korpanty, Kendra Worthington, Colin Luo, Karen L Christman and Nathan C Gianneschi | Summary: ABSTRACT Nanoparticles that undergo a localized morphology change to target areas of inflammation have been previously developed but are limited by their lack of biodegradability. In this paper, […]

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Circuit dissection and functional validation of a cross-species emotional biomarker

Posted by klaurent November 11, 2022November 21, 2022UCSF

Kavli Affiliate: Edward Chang, Vikaas Sohal | Authors: Adam Jackson, Josh Cohen, Aarron Phensy, Edward F Chang, Heather Dawes and Vikaas Sohal | Summary: ABSTRACT Emotional responses arise from limbic circuits including the hippocampus and amygdala. In the human brain, beta-frequency communication between these structures correlates with self-reported mood and anxiety. However, both the mechanism […]

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$d$-wave Superconductivity, Pseudogap, and the Phase Diagram of $t$-$t’$-$J$ Model at Finite Temperature

Posted by dbos November 11, 2022UCAS

Kavli Affiliate: Gang Su | First 5 Authors: Dai-Wei Qu, Bin-Bin Chen, Xin Lu, Qiaoyi Li, Shou-Shu Gong | Summary: Recently, a robust $d$-wave superconductivity has been unveiled in the ground state of the 2D $t$-$t’$-$J$ model — with both nearest-neighbor ($t$) and next-nearest-neighbor ($t’$) hoppings — through the density matrix renormalization group calculations in […]

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A Multi-Qubit Quantum Gate Using the Zeno Effect

Posted by klaurent November 11, 2022Berkeley

Kavli Affiliate: Birgitta Whaley | First 5 Authors: Philippe Lewalle, Leigh S. Martin, Emmanuel Flurin, Song Zhang, Eliya Blumenthal | Summary: The Zeno effect, in which repeated observation freezes the dynamics of a quantum system, stands as an iconic oddity of quantum mechanics. When a measurement is unable to distinguish between states in a subspace, […]

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