Kavli Affiliate: Taizan Watari | Summary:A characterization of rational superconformal field theories (SCFTs) on 1+1 dimensions with Ricci-flat Kahler targets was proposed by S. Gukov and C. Vafa in terms of the Hodge structure of the target space. The article [arXiv:2205.10299] refined this idea and extracted a set of necessary conditions for a $T^4$-target N=(1,1) […]
Kavli Affiliate: Stephen Strittmatter | Authors: Hideyuki Takahashi, Sanaea Bhagwagar, Sarah H. Nies, Marius T. Chiasseu, Guilin Wang, Ian R. Mackenzie and Stephen M. Strittmatter | Summary: Comorbid proteinopathies are observed in many neurodegenerative disorders including Alzheimer’s disease (AD), increase with age, and influence clinical outcomes, yet the mechanisms remain ill-defined. Here, we show that […]
Kavli Affiliate: Shawn Ferguson | Authors: Narayana Yadavalli and Shawn M. Ferguson | Summary: Variants in leucine rich repeat kinase 2 (LRRK2) that increase kinase activity confer risk for sporadic and familial forms of Parkinson’s disease. However, LRRK2-dependent cellular processes responsible for disease risk remain uncertain. Here we show that LRRK2 negatively regulates lysosome degradative […]
Kavli Affiliate: Nenad Sestan | Authors: Suel-Kee Kim, Seungmae Seo, Genevieve Stein-O’Brien, Amritha Jaishankar, Kazuya Ogawa, Nicola Micali, Victor Luria, Amir Karger, Yanhong Wang, Thomas M. Hyde, Joel E. Kleinman, Ty Voss, Elana J. Fertig, Joo-Heon Shin, Roland Bürli, Alan J. Cross, Nicholas J. Brandon, Daniel R. Weinberger, Joshua G. Chenoweth, Daniel J. Hoeppner, Nenad […]
Kavli Affiliate: David Rowitch | Authors: Patricia Renz, Daniel Surbek, Valérie Haesler, Vera Tscherrig, Eric J Huang, Manideep Chavali, Shane Liddelow, David Rowitch, Andreina Schoeberlein and Amanda Brosius Lutz | Summary: The role of reactive astrocytes in perinatal white matter injury (WMI) is unclear. In a mouse model of WMI, we provide evidence that impairing […]
Kavli Affiliate: Michael Beer | Authors: David Yao, Josh Tycko, Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis, Ava Mackay-Smith, Benjamin R. Doughty, Idan Gabdank, Henri Schmidt, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunahi Luo, Keith Siklenka, Galip Gurkan Yardimci, The ENCODE4 Consortium, Ryan Tewhey, Anshul Kundaje, William J. Greenleaf, Pardis […]
Kavli Affiliate: Jeevak Parpia | Summary:By monitoring the quality factor of a quartz tuning fork oscillator we have observed a fluctuation-driven reduction in the viscosity of bulk $^3$He in the normal state near the superfluid transition temperature, $T_c$. These fluctuations, which are only found within $100 μ$K of $T_c$, play a vital role in the […]
Kavli Affiliate: Sarah N. T. Heine | Summary:The flight of the Micro-X sounding rocket on July 22, 2018 marked the first operation of Transition-Edge Sensors and their SQUID readouts in space. The instrument combines the microcalorimeter array with an imaging mirror to take high-resolution spectra from extended X-ray sources. The first flight target was the […]
Kavli Affiliate: Michael P. Brenner | First 5 Authors: Jacob Page, Peter Norgaard, Michael P. Brenner, Rich R. Kerswell, | Summary: A dynamical systems approach to turbulence envisions the flow as a trajectory through a high-dimensional state space transiently visiting the neighbourhoods of unstable simple invariant solutions (E. Hopf, Commun. Appl. Maths 1, 303, 1948). […]
Kavli Affiliate: Mohammad Mirhosseini | Summary:We demonstrate a superconducting artificial atom with strong unidirectional coupling to a microwave photonic waveguide. Our artificial atom is realized by coupling a transmon qubit to the waveguide at two spatially separated points with time-modulated interactions. Direction-sensitive interference arising from the parametric couplings in our scheme results in a non-reciprocal […]