The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2

Posted by klaurent UCSD / Salk

Kavli Affiliate: Jose Suarez Lopez | Authors: Selim Chaib, José Alberto López-Domínguez, Marta Lalinde, Neus Prats, Inés Marín, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Marta Escorihuela, Sandra Pérez-Ramos, Fatima Al-Shahrour, Timothy P Cash, Tamara Tchkonia, James L Kirkland, Joaquín Arribas and Manuel Serrano | Summary: Abstract Anti-cancer […]


Continue.. The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2

Astrocyte-like CEPsh glia responds to the stressful environments

Posted by klaurent UCSF

Kavli Affiliate: Noelle Letoile | Authors: Evangeline Chien, Angel Jacob Garcia, RASHMI CHANDRA and Noelle L’Etoile | Summary: Abstract While astrocytes are known to be important for development and nourishment of the nervous system, the field is just beginning to explore how astrocytes respond to environmental stimuli. Using Caenorhabditis elegans and their astrocyte-equivalent, CEPsh, we […]


Continue.. Astrocyte-like CEPsh glia responds to the stressful environments

Astrocyte-like CEPsh glia respond to stress

Posted by klaurent UCSF

Kavli Affiliate: Noelle Letoile | Authors: Evangeline Chien, Angel Jacob Garcia, Noelle L’Etoile and RASHMI CHANDRA | Summary: Abstract While astrocytes are known to be important for development and nourishment of the nervous system, the field is just beginning to explore how astrocytes respond to environmental stimuli. Using Caenorhabditis elegans and their astrocyte-equivalent, CEPsh, we […]


Continue.. Astrocyte-like CEPsh glia respond to stress

Nonadditive Interactions Unlock Small-Particle Mobility in Binary Colloidal Monolayers

Posted by klaurent Berkeley

Kavli Affiliate: Naomi Ginsberg | Summary:We examine the organization and dynamics of binary colloidal monolayers composed of micron-scale silica particles interspersed with smaller-diameter silica particles that serve as minority component impurities. These binary monolayers are prepared at the surface of ionic liquid droplets over a range of size ratios ($σ=0.16-0.66$) and are studied with low-dose […]


Continue.. Nonadditive Interactions Unlock Small-Particle Mobility in Binary Colloidal Monolayers

Nonadditive Interactions Unlock Small-Particle Mobility in Binary Colloidal Monolayers

Posted by klaurent Berkeley

Kavli Affiliate: Naomi S. Ginsberg | First 5 Authors: Jonathan G. Raybin, Rebecca B. Wai, Naomi S. Ginsberg, , | Summary: We examine the organization and dynamics of binary colloidal monolayers composed of micron-scale silica particles interspersed with smaller-diameter silica particles that serve as minority component impurities. These binary monolayers are prepared at the surface […]


Continue.. Nonadditive Interactions Unlock Small-Particle Mobility in Binary Colloidal Monolayers

Efficiently computing the Uhlmann fidelity for density matrices

Posted by klaurent Oxford

Kavli Affiliate: Andrew Baldwin | Summary:We consider the problem of efficiently computing the Uhlmann fidelity in the case when explicit density matrix descriptions are available. We derive an alternative formula which is simpler to evaluate numerically, saving a factor of 10 in time for large matrices. | Search Query: arXiv Query: search_query=au:”Baldwin Andrew J.”&id_list=&start=0&max_results=10Read More


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Human FcγRIIIa activation on splenic macrophages drives the in vivo pathogenesis of dengue disease

Posted by klaurent Rockefeller

Kavli Affiliate: Charles Rice | Authors: Rachel Yamin, Kevin S Kao, Margaret R MacDonald, Tineke Cantaert, Charles M Rice, Jeffrey V Ravetch and Stylianos Bournazos | Summary: Abstract Although dengue virus (DENV) infection typically causes asymptomatic disease, DENV-infected patients can experience severe complications. A risk factor for symptomatic disease is pre-existing anti-DENV IgG antibodies. Cellular […]


Continue.. Human FcγRIIIa activation on splenic macrophages drives the in vivo pathogenesis of dengue disease

The molecular genetic landscape of human brain size variation

Posted by klaurent UCSD / Salk

Kavli Affiliate: Eric Courchesne | Authors: Jakob Seidlitz, Travis T. Mallard, Jacob W. Vogel, Younga H. Lee, Varun Warrier, Gareth Ball, Oskar Hansson, Leanna M. Hernandez, Ayan S. Mandal, Konrad Wagstyl, Michael V. Lombardo, Eric Courchesne, Joseph T. Glessner, Theodore D. Satterthwaite, Richard A.I. Bethlehem, Lifespan Brain Chart Consortium, Shinya Tasaki, Bernard Ng, Chris Gaiteri, […]


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An inhibitory plasticity mechanism for world structure inference by hippocampal replay

Posted by klaurent Columbia

Kavli Affiliate: Attila Losonczy | Authors: Zhenrui Liao, Darian Hadjiabadi, Satoshi Terada, Ivan Soltesz and Attila Losonczy | Summary: Summary Memory consolidation assimilates recent experiences into long-term memory. This process requires the replay of learned sequences, though the content of these sequences remains controversial. Recent work has shown that the statistics of replay deviate from […]


Continue.. An inhibitory plasticity mechanism for world structure inference by hippocampal replay

Full forward model of galaxy clustering statistics with AbacusSummit lightcones

Posted by klaurent Stanford

Kavli Affiliate: Tom Abel | First 5 Authors: Sihan Yuan, Boryana Hadzhiyska, Tom Abel, , | Summary: Novel summary statistics beyond the standard 2-point correlation function (2PCF) are necessary to capture the full astrophysical and cosmological information from the small-scale (r < 30Mpc/h) galaxy clustering. However, the analysis of beyond-2PCF statistics on small scales is […]


Continue.. Full forward model of galaxy clustering statistics with AbacusSummit lightcones