Kavli Affiliate: Reza Shadmehr | Authors: Jafar Doostmohammadi, Nazanin Mohammadrezaei, Hisham Elseweifi, Alana Chandler, Elijah Taeckens and Reza Shadmehr | Summary: Neurons in the brain are often many synapses away from motoneurons, yet if a movement results in error, each distant neuron needs a teacher that considers its specific contribution to production of that […]
Kavli Affiliate: Kay Tye | Authors: Reesha Patel, Kelly Kim, Makenzie Patarino, Rachelle Pamintuan, Felix Taschbach, Hao Li, Bitna Joo, Anna Pallé, Xianru Yu, Christopher R Lee, Aniek van Hoek, Jesse White, Rogelio Castro, Christian Cazares, Raymundo Miranda, Caroline Jia, Jeremy Delahanty, Kanha Batra, Laurel Keyes, Avraham Libster, Romy W. Wichmann, Talmo Pereira, Marcus […]
Kavli Affiliate: Jeremy Nathans | Authors: Philip V Seegren, Amir Rattner, Philip M Smallwood and Jeremy Nathans | Summary: Neonatal bacterial meningitis is a leading cause of infant morbidity and mortality, yet the molecular and cellular basis of the leptomeningeal response to infection remains poorly defined. Here, we study a mouse model of neonatal E. […]
Kavli Affiliate: Roderick MacKinnon | Authors: Maria Falzone, Priyam Banerjee and Roderick MacKinnon | Summary: PLCβ enzymes cleave PIP2 from the plasma membrane, producing IP3 and DAG, which regulate intracellular Ca2+ levels and protein kinase C activity, respectively. They are regulated by GPCR signaling through the G proteins Gβγ and Gαq and have been shown […]
Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Keri Martinowich | Authors: Helena L Crowell, Yixing Dong, Ilaria Billato, Peiying Cai, Martin Emons, Samuel Gunz, Boyi Guo, Mengbo Li, Alexandru Mahmoud, Artür Manukyan, Hervé Pagès, Pratibha Panwar, Shreya Rao, Callum J Sargeant, Lori Shepherd Kern, Marcel Ramos, Jieran […]
Kavli Affiliate: Seth Blackshaw | Authors: Jianming Shao, Xuan Bao, Ismail Yaman, Ye Zheng, Jun Wang, Jin Li, Tingting Yang, Jinjing Jian, Jean Li, Seth Blackshaw, Kapil Bharti, Margo Clarke, Dwight E. Stambolian, Ching-Hwa Sung, Jie J. Zheng, Davide Ortolan, Sarah X. Zhang, Ruchi Sharma, Richard H. Scheuermann, Ajith V. Pankajam, Ahmed H. Ghobashi, […]
Kavli Affiliate: Charles M. Rice | Authors: Catherine A Freije, Georgios Dangas, Antonis Athanasiadis, Evgenia Moschogianni, Madeleine K Sanders, Allan Henrique Depieri Cataneo, Chloe K Boehm, Maria Bousali, Dar-Yin Li, Sooyoung Lee, Guillaume Cornelis, Gary Lo, Leah B Soriaga, Amalio Telenti, Julia di Iulio, Ana L P Mosimann, Juliano Bordignon, Kirin Karver, Lukas Fu, […]
Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Roderick MacKinnon | Authors: Venkata Shiva Mandala, Chen Zhao, Qiuying Chen, Steven Gross, Jacob B Geri and Roderick MacKinnon | Summary: The plasma membrane of cells is known to be heterogeneous with regards to the spatial distribution of proteins and […]
Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Devanand Manoli | Authors: Mohamed Abuelanin, Gulhan Kaya, Juniper A Lake, Christine Lambert, Melody V Wu, Kristen Berendzen, Ksenia Krasheninnikova, Jonathan MD Wood, Nancy G Solomon, Zoe R Donaldson, Karen L Bales, Kerstin Howe, Jonas Korlach, Devanand S Manoli, Jessica […]
Kavli Affiliate: Loren Frank | Authors: Abhilasha Joshi, Alison E. Comrie, Samuel Bray, Abhijith Mankili, Jennifer A. Guidera, Rhino Nevers, Xulu Sun, Emily Monroe, Viktor Kharazia, Ryan Ly, Daniela Astudillo Maya, Denisse Morales-Rodriguez, Jai Yu, Anna Kiseleva, Victor Perez and Loren M. Frank | Summary: The ability to rapidly learn and retrieve salient information about […]