Signatures of visuospatial information foraging during learning of complex environments

Kavli Affiliate: Daphna Shohamy | Authors: David L Barack, Akram Bakkour, Daphna Shohamy and C Daniel Salzman | Summary: Abstract In the real world, making sequences of decisions to achieve goals often depends upon the ability to learn aspects of the environment that are not directly perceptible. Learning these so-called latent features requires seeking information […]


Continue.. Signatures of visuospatial information foraging during learning of complex environments

Canonical retinotopic shifts under an inverse force field explain predictive remapping

Kavli Affiliate: Michael Keiser | Authors: Laura M Gunsalus, Michael J. Keiser and Katherine S Pollard | Summary: ABSTRACT Predictive remapping — the ability of cells in retinotopic brain areas to transiently exhibit spatio-temporal retinotopic shifts beyond the spatial extent of their classical receptive fields — has been proposed as a primary mechanism that stabilizes […]


Continue.. Canonical retinotopic shifts under an inverse force field explain predictive remapping

Rapid fluctuations in functional connectivity of cortical networks encode spontaneous

Kavli Affiliate: Michael Crair, Jessica Cardin | Authors: Hadas Benisty, Daniel Barson, Andrew H. Moberly, Sweyta Lohani, Ronald R. Coifman, Gal Mishne, Michael C. Crair, Jessica A. Cardin and Michael J. Higley | Summary: Abstract Experimental work across a variety of species has demonstrated that spontaneously generated behaviors are robustly coupled to variation in neural […]


Continue.. Rapid fluctuations in functional connectivity of cortical networks encode spontaneous

Rapid fluctuations in functional connectivity of cortical networks encode spontaneous behavior

Kavli Affiliate: Jessica Cardin & Michael Higley | Authors: Hadas Benisty, Andrew H Moberly, Sweyta Lohani, Daniel Barson, Ronald R Coifman, Gal Mishne, Jessica A Cardin and Michael J Higley | Summary: Abstract Experimental work across a variety of species has demonstrated that spontaneously generated behaviors are robustly coupled to variation in neural activity within […]


Continue.. Rapid fluctuations in functional connectivity of cortical networks encode spontaneous behavior

Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus

Kavli Affiliate: Arnold Kriegstein | Authors: Brian R Herb, Hannah J Glover, Aparna Bhaduri, Carlo Colantuoni, Tracy L Bale, Kimberly Siletti, Sten Linnarsson, Rebecca D Hodge, Ed Lein, Arnold Kriegstein, Claudia Doege and Seth A Ament | Summary: Abstract The development and diversity of neuronal subtypes in the human hypothalamus has been insufficiently characterized. We […]


Continue.. Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus

Using Biological Constraints to Improve Prediction in Precision Oncology

Kavli Affiliate: Donald Geman, Laurent Younes | Authors: Mohamed Omar, Wikum Dinalankara, Lotte Mulder, Tendai Coady, Claudio Zanettini, Eddie Luidy Imada, Laurent Younes, Donald Geman and Luigi Marchionni | Summary: Abstract Many gene signatures have been developed by applying machine learning (ML) on omics profiles, however, their clinical utility is often hindered by limited interpretability […]


Continue.. Using Biological Constraints to Improve Prediction in Precision Oncology

Heritable differences in synaptic zinc-transporter levels drive variation in learned birdsong

Kavli Affiliate: Michael Brainard | Authors: DG. Mets, W. H. Mehaffey, B. M. Colquitt and M. S. Brainard | Summary: Abstract The authors have withdrawn this manuscript. During revision of our manuscript, we carried out several lines of additional experiments and analyses that failed to fully support and reproduce the results previously presented in Figure […]


Continue.. Heritable differences in synaptic zinc-transporter levels drive variation in learned birdsong

Alzheimer’s-associated upregulation of mitochondria-associated ER membranes after traumatic brain injury

Kavli Affiliate: Daphna Shohamy | Authors: Jonathan Nicholas, Christian Amlang, Chi-Ying Lin, Leila Montaser-Kouhsari, Natasha Desai, Ming-Kai Pan, Sheng-Han Kuo and Daphna Shohamy | Summary: Abstract Traumatic brain injury (TBI) can lead to neurodegenerative diseases such as Alzheimer’s disease (AD) through mechanisms that remain incompletely characterized. Similar to AD, TBI models present with cellular metabolic […]


Continue.. Alzheimer’s-associated upregulation of mitochondria-associated ER membranes after traumatic brain injury

Age-specific mechanisms regulate neural crest and mesodermal contribution to the enteric nervous system in health and disease

Kavli Affiliate: Loyal Goff | Authors: Subhash Kulkarni, Monalee Saha, Alpana Singh, Jared Slosberg, Sushma Nagaraj, Laren S Becker, Chengxiu Zhang, Alicia Bukowski, Zhuolun Wang, Guosheng Liu, Jenna Leser, Mithra Kumar, Shriya Bakhshi, Matthew J Anderson, Mark Lewandoski, Elizabeth Vincent, Loyal Goff and Pankaj Jay Pasricha | Summary: Abstract The enteric nervous system (ENS), a […]


Continue.. Age-specific mechanisms regulate neural crest and mesodermal contribution to the enteric nervous system in health and disease

Phase alignment of low-frequency neural activity to the amplitude envelope of speech reflects evoked responses to acoustic edges, not oscillatory entrainment

Kavli Affiliate: Edward Chang | Authors: Yulia Oganian, Katsuaki Kojima, Assaf Breska, Chang Cai, Anne Findlay, Edward F Chang and Srikantan Nagarajan | Summary: Abstract The amplitude envelope of speech is crucial for accurate comprehension. Considered a key stage in speech processing, the phase of neural activity in the theta-delta bands (1 – 10 Hz) […]


Continue.. Phase alignment of low-frequency neural activity to the amplitude envelope of speech reflects evoked responses to acoustic edges, not oscillatory entrainment