Neuroscience – Page 20 – Kavli Institute Pre-Print Publications

Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits

Posted by dbos November 17, 2024November 25, 2024UCSF

Kavli Affiliate: Adam Gazzaley | Authors: Lorenzo Pasquini, Jakub Vohryzek, Anira Escrichs, Yonatan Sanz Perl, Adrian Ponce-Alvarez, Sebastian Idesis, Manesh Girn, Leor Roseman, Jennifer M Mitchell, Adam Gazzaley, Morten Kringelbach, David J Nutt, Taylor Lyons, Robin L Carhart-Harris and Gustavo Deco | Summary: Psilocybin has been shown to induce fast and sustained improvements in mental […]

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Interspecies Organoids Reveal Human-Specific Molecular Features of Dopaminergic Neuron Development and Vulnerability

Posted by dbos November 15, 2024November 25, 2024UCSF

Kavli Affiliate: Alex Pollen | Authors: Sara Nolbrant, Jenelle L. Wallace, Jingwen Ding, Tianjia Zhu, Jess L. Sevetson, Janko Kajtez, Isabella A. Baldacci, Emily K. Corrigan, Kaylynn Hoglin, Reed McMullen, Matthew T. Schmitz, Arnar Breevoort, Dani Swope, Fengxia Wu, Bryan J. Pavlovic, Sofie R. Salama, Agnete Kirkeby, Hao Huang, Nathan K. Schaefer and Alex A. […]

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Nuclear DNA replication in Leishmania major relies on a single constitutive origin per chromosome supplemented by thousands of stochastic initiation events

Posted by dbos November 14, 2024November 25, 2024UCSD / Salk

Kavli Affiliate: Gabriel Silva | Authors: Jeziel D Damasceno, Gabriel LA Silva, Catarina A Marques, Marija Krasilnikova, Craig Lapsley, Dario Beraldi and Richard McCulloch | Summary: Understanding genome duplication requires characterisation of the locations where DNA replication initiates, termed origins. Genome-wide mapping of DNA replication origins has mainly been derived from population-based techniques, with only […]

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Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction

Posted by dbos November 12, 2024November 25, 2024Columbia

Kavli Affiliate: Ann McDermott | Authors: Cassandra A Chartier, Virgil A Woods, Yunyao Xu, Anne E van Vlimmeren, Marko Jovanovic, Ann E McDermott, Daniel A Keedy and Neel H Shah | Summary: The rapid identification of protein-protein interactions has been significantly enabled by mass spectrometry (MS) proteomics-based methods, including affinity purification-MS, crosslinking-MS, and proximity-labeling proteomics. […]

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Optogenetic Central Amygdala Stimulation is Highly Reinforcing and Strongly Outcompetes Fentanyl Self-Administration in Male, but not Female, Rats

Posted by dbos November 10, 2024November 18, 2024Hopkins

Kavli Affiliate: Patricia Janak | Authors: Emma Chaloux-Pinette, Maricela Vela Mirelez-Prince, Samantha Soto, Kirtana Ananth, Xiao Tong, Vanessa Silva, Daniela Rodriguez and Patricia H Janak | Summary: The central nucleus of the amygdala plays a key role in many aspects of substance use disorders, in particular biasing behaviors toward one drug or natural reward over […]

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Cephalopod Sex Determination and its Ancient Evolutionary Origin

Posted by dbos November 7, 2024November 18, 2024Columbia

Kavli Affiliate: Scott Small | Authors: Gabrielle C. Coffing, Silas Tittes, Scott T. Small, Jeremea O. Songco-Casey, Denise M. Piscopo, Judit R. Pungor, Adam C Miller, Cristopher Niell and Andrew D. Kern | Summary: Octopuses, squids, and cuttlefishes – the coleoid cephalopods – are a remarkable branch in the tree of life whose members exhibit […]

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Recurrent Connectivity Shapes Spatial Coding in Hippocampal CA3 Subregions

Posted by dbos November 7, 2024November 18, 2024Columbia

Kavli Affiliate: Darcy Peterka and Attila Losonczy | Authors: Eunji Kong, Erfan Zabeh, Zhenrui Liao, Tiberiu S. Mihaila, Darcy S. Peterka, Caroline Wilson, Charan Santhirasegaran, Attila Losonczy and Tristan Geiller | Summary: Stable and flexible neural representations of space in the hippocampus are crucial for navigating complex environments. However, how these distinct representations emerge from […]

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Single Objective Light Sheet Microscopy allows high-resolution in vivo brain imaging of Drosophila

Posted by dbos November 7, 2024November 18, 2024UCSD / Salk

Kavli Affiliate: Mark Ellisman | Authors: Francisco Joaquín Tassara, Mariano Barella, Lourdes Simó, Mailen Folgueira, Micaela Rodríguez-Caron, Juan Ignacio Ispizua, Mark H. Ellisman, Horacio O. de la Iglesia, M. Fernanda Ceriani and Julián Gargiulo | Summary: In vivo imaging of dynamic sub-cellular brain structures in Drosophila melanogaster is key to understanding several phenomena in neuroscience. […]

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Electrical Coordinated Reset Stimulation Induces Network Desynchronization in an in Vivo Model of Status Epilepticus

Posted by dbos November 7, 2024November 18, 2024Hopkins

Kavli Affiliate: Sridevi Sarma | Authors: Daniel Ehrens, Fadi Aeed, Yara Otor, Vivek Charu, Babak Razavi, Sridevi V Sarma, Yitzhak Schiller and Peter A Tass | Summary: Epilepsy, a neurological disorder characterized by recurrent seizures, profoundly impacts individuals worldwide. Various electrical stimulation protocols have been investigated to mitigate epileptic seizures, among which Coordinated Reset (CR) […]

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Resting-state connectivity modifies the effects of amyloid on cognitive and physical function: evidence for network-based cognitive reserve

Posted by dbos November 7, 2024November 18, 2024Hopkins

Kavli Affiliate: Michael Miller | Authors: Paul J Laurienti, Stephen B Kritchevsky, Robert G Lyday, Michael E Miller, Samuel N Lockhart, Melissa M Rundle, Christina E Hugenschmidt, Jonathan H Burdette, Heather M Shappell, Haiying Chen, Laura D Baker, Blake R Neyland and Roee Holtzer | Summary: Cognitive and physical function are interrelated in aging co-occurring […]

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