An encyclopedia of enhancer-gene regulatory interactions in the human genome

Kavli Affiliate: Michael Beer | Authors: Andreas R. Gschwind, Kristy S. Mualim, Alireza Karbalayghareh, Maya U. Sheth, Kushal K. Dey, Evelyn Jagoda, Ramil N. Nurtdinov, Wang Xi, Anthony S. Tan, Hank Jones, X. Rosa Ma, David Yao, Joseph Nasser, Ziga Avsec, Benjamin T. James, Muhammad S. Shamim, Neva C. Durand, Suhas S. P. Rao, Ragini […]


Continue.. An encyclopedia of enhancer-gene regulatory interactions in the human genome

Investigating egocentric tuning in hippocampal CA1 neurons using simulated data

Kavli Affiliate: Edvard Moser & May-Britt Moser | Authors: Jordan Carpenter, Jan Sigurd Blackstad, David Tingley, Valentin A. Normand, Edvard I. Moser, May-Britt Moser and Benjamin A. Dunn | Summary: Navigation requires integrating sensory information with a stable schema to create a dynamic map of an animal’s position using egocentric and allocentric coordinate systems. In […]


Continue.. Investigating egocentric tuning in hippocampal CA1 neurons using simulated data

Microbiota-dependent early life programming of gastrointestinal motility

Kavli Affiliate: David Linden | Authors: Mary E Frith, Purna C Kashyap, David R Linden, Betty Theriault and Eugene B Chang | Summary: Gastrointestinal microbes modulate peristalsis and stimulate the enteric nervous system (ENS), whose development, as in the central nervous system (CNS), continues into the murine postweaning period. Given that adult CNS function depends […]


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Ammonia-oxidizing archaea and bacteria differentially contribute to ammonia oxidation in soil under precipitation gradients and land legacy

Kavli Affiliate: Charles M. Rice | Authors: Soumyadev Sarkar, Anna Kazarina, Paige M. Hansen, Kaitlyn Ward, Christopher Hargreaves, Nicholas Reese, Qinghong Ran, Willow Kessler, Ligia F.T. de Souza, Terry D. Loecke, Marcos V.M. Sarto, Charles W. Rice, Lydia H. Zeglin, Benjamin A. Sikes and Sonny T.M. Lee | Summary: Global change has accelerated the nitrogen […]


Continue.. Ammonia-oxidizing archaea and bacteria differentially contribute to ammonia oxidation in soil under precipitation gradients and land legacy

Abstract representations emerge in human hippocampal neurons during inference behavior

Kavli Affiliate: Stefano Fusi & Daniel Salzman | Authors: Hristos Spiridonos Courellis, Juri Minxha, Araceli Ramirez Cardenas, Daniel L Kimmel, Chrystal M Reed, Taufik A Valiante, C. Daniel Salzman, Adam N Mamelak, Ralph Adolphs, Stefano Fusi and Ueli Rutishauser | Summary: Humans have the remarkable cognitive capacity to rapidly adapt to changing environments. Central to […]


Continue.. Abstract representations emerge in human hippocampal neurons during inference behavior

Aberrant hippocampal Ca2+ micro-waves following synapsin-dependent adenoviral expression of Ca2+ indicators

Kavli Affiliate: Rafael Yuste | Authors: Nicola Masala, Manuel Mittag, Eleonora Ambrad Giovannetti, Darik A O’Neil, Fabian J Distler, Peter Rupprecht, Fritjof Helmchen, Rafael Yuste, Martin Fuhrmann, Heinz Beck, Michael Wenzel and Tony Kelly | Summary: Genetically encoded calcium indicators (GECIs) such as GCaMP are an invaluable tool in neuroscience to monitor neuronal activity using […]


Continue.. Aberrant hippocampal Ca2+ micro-waves following synapsin-dependent adenoviral expression of Ca2+ indicators

Generation and characterization of a multi-functional panel of monoclonal antibodies for SARS-CoV-2 research and treatment

Kavli Affiliate: Charles M. Rice | Authors: Lila D. Patterson, Benjamin D. Dubansky, Brooke H. Dubansky, Shannon Stone, Mukesh Kumar and Charles D Rice | Summary: The Coronavirus disease 2019 (COVID19) pandemic caused by Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) is an ongoing threat to global public health. To this end, intense efforts are underway to […]


Continue.. Generation and characterization of a multi-functional panel of monoclonal antibodies for SARS-CoV-2 research and treatment

Social isolation recruits amygdala-cortical circuitry to escalate alcohol drinking

Kavli Affiliate: Kay Tye | Authors: Reesha Patel, Makenzie Patarino, Kelly Kim, Rachelle Pamintuan, Felix Taschbach, Hao Li, Christopher Lee, Aniek van Hoek, Rogelio Castro, Christian Cazares, Ray Miranda, Caroline Jia, Jeremy Delahanty, Kanha Batra, Laurel Keyes, Avraham Libster, Romy W. Wichmann, Talmo Pereira, Marcus Benna and Kay M. Tye | Summary: How do social […]


Continue.. Social isolation recruits amygdala-cortical circuitry to escalate alcohol drinking

A combined DTI-fMRI approach for optimizing the delineation of posteromedial vs. anterolateral entorhinal cortex

Kavli Affiliate: Menno Witter | Authors: Ingrid Framas Syversen, Daniel Reznik, Menno P. Witter, Asgeir Kobro-Flatmoen, Tobias Navarro Schroder and Christian F. Doeller | Summary: In the entorhinal cortex (EC), attempts have been made to identify the human homologue regions of the medial (MEC) and lateral (LEC) subdivision using either functional magnetic resonance imaging (fMRI) […]


Continue.. A combined DTI-fMRI approach for optimizing the delineation of posteromedial vs. anterolateral entorhinal cortex

SELENOT regulates endoplasmic reticulum calcium flux via SERCA2 and maintains dopaminergic DAT to protect against attention deficit hyperactivity disorder in mice

Kavli Affiliate: Li Zhao | Authors: Qing Guo, Zhao-Feng Li, Dong-Yan Hu, Pei-Jun Li, Kai-Nian Wu, Hui-Hui Fan, Jie Deng, Hong-Mei Wu, Xiong Zhang and Jian-Hong Zhu | Summary: Attention deficit and hyperactivity disorder (ADHD) is a prevalent developmental disorder. SELENOT is an endoplasmic reticulum-resident selenocysteine-containing protein. We aimed to investigate the role of SELENOT […]


Continue.. SELENOT regulates endoplasmic reticulum calcium flux via SERCA2 and maintains dopaminergic DAT to protect against attention deficit hyperactivity disorder in mice