Neuroscience – Page 17 – Kavli Institute Pre-Print Publications

Cigarette smoke and biological age induce degenerative heterogeneity in retinal pigment epithelium

Posted by dbos January 28, 2025February 10, 2025Hopkins

Kavli Affiliate: Seth Blackshaw | Authors: Krishna Singh, yang jin, Mingwen Hu, Isabella Pallazo, Marisol Cano,, Thanh Hoang, Imran Bhutto, Shusheng Wang, Debasish Sinha, Seth Blackshaw, Jiang Qian and James T. Handa | Summary: Environmental exposure such as cigarette smoke induces epigenetic changes that can induce degenerative heterogeneity and accelerate aging. In early age-related macular […]

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KV1.8 (Kcna10) potassium channels enhance fast, linear signaling in vestibular hair cells and facilitate vestibulomotor reflexes and balance

Posted by dbos January 28, 2025February 10, 2025Hopkins

Kavli Affiliate: Kathleen Cullen | Authors: Hannah R Martin, Brandie Morris Verdone, Omar Lopez-Ramirez, Merrill Green, Dana Silvian, Emily Scott, Kathleen E Cullen and Ruth Anne Eatock | Summary: Vestibular hair cells (HCs) faithfully and rapidly detect head motions and gravity, driving motor reflexes that stabilize balance and gaze during locomotion. With the transition from […]

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Non-Visual Light Sensing Enhances Behavioral Memory and Drives Gene Expression in C. elegans

Posted by dbos January 28, 2025February 10, 2025UCSF

Kavli Affiliate: Noelle L’Etoile | Authors: Zhijian Ji, Bingying Wang, Junqiang Liu, Rashmi K. Chandra, Winnie Yang, Yong Long, Michael Egan, Noelle L’Etoile and Dengke K. Ma | Summary: Visible light influences a range of physiological processes, yet how animals respond to it independently of the visual system remains largely unknown. Here, we uncover a […]

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A brainstem map of orofacial rhythms

Posted by dbos January 27, 2025February 10, 2025UCSD / Salk

Kavli Affiliate: David Kleinfeld | Authors: Heet Kaku, Liu D Liu, Runbo Gao, Steven West, Song-Mao Liao, Arseny Finkelstein, David Kleinfeld, Alyse Thomas, Sri Laasya Tipparaju, Karel Svoboda and Nuo Li | Summary: Rhythmic orofacial movements, such as eating, drinking, or vocalization, are controlled by distinct premotor oscillator networks in the brainstem. Orofacial movements must […]

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Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant

Posted by dbos January 27, 2025February 10, 2025Rockefeller

Kavli Affiliate: Daniel Kronauer | Authors: Kip D Lacy, Jina Lee, Kathryn Rozen-Gagnon, Wei Wang, Thomas S Carroll and Daniel J C Kronauer | Summary: Sex determination is a developmental switch that triggers sex-specific developmental programs. This switch is “flipped” by the expression of genes that promote male- or female-specific development. Many lineages have evolved […]

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The geometry of the neural state space of decisions

Posted by dbos January 25, 2025February 5, 2025Columbia

Kavli Affiliate: Kenneth Miller | Authors: Mauro M. Monsalve-Mercado and Kenneth D Miller | Summary: How do populations of neurons collectively encode and process information during cognitive tasks? We analyze high-yield population recordings from the macaque lateral intraparietal area (LIP) during a reaction-time random-dot-motion direction-discrimination task. We find that the trajectories of neural population activity […]

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Exact linear theory of perturbation response in a space- and feature-dependent cortical circuit model

Posted by dbos January 24, 2025February 5, 2025Columbia

Kavli Affiliate: Kenneth Miller | Authors: Ho Yin Chau, Kenneth D Miller and Agostina Palmigiano | Summary: What are the principles that govern the responses of cortical networks to their inputs and the emergence of these responses from recurrent connectivity? Recent experiments have probed these questions by measuring cortical responses to two-photon optogenetic perturbations of […]

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Adaptation shapes the representational geometry in mouse V1 to efficiently encode the environment

Posted by dbos January 24, 2025February 5, 2025Columbia

Kavli Affiliate: Stefano Fusi and Kenneth Miller | Authors: Mario Dipoppa, Ramon Nogueira, Stéphane Bugeon, Yoni Friedman, Charu B. Reddy, Kenneth D. Harris, Dario L. Ringach, Kenneth D. Miller, Matteo Carandini and Stefano Fusi | Summary: Allogeneic stem cell transplant (alloSCT) for patients with relapsed/refractory chronic lymphocytic Sensory adaptation dynamically changes neural responses as a […]

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Evolution of chronic lymphocytic leukemia after allogeneic stem cell transplant

Posted by dbos January 24, 2025February 5, 2025Rockefeller

Kavli Affiliate: Li Zhao | Authors: Haven R Garber, Danwei Wang, Celine Kerros, Hannah C Beird, Xizeng Mao, Nina G Howard, Jianhua Zhang, Jason Roszik, John P Miller, Paul Leonard, Yu Cao, Li Zhao, Xingzhi Song, Sahil Seth, Pei Lin, Huandong Sun, Lisa S St John, Sijie Lu, William Wierda, Issa F Khouri, Karen Clise-Dwyer, […]

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Mitochondrial ROS and HIF-1α signalling mediate critical period plasticity

Posted by dbos Hopkins

Kavli Affiliate: Michael Miller | Authors: Daniel Sobrid-Camean, Bramwell Coulson, Michael Miller, Matthew CW Oswald, Tom Pettini, Richard A Baines and Matthias Landgraf | Summary: As developing networks transition from spontaneous irregular to patterned activity, they undergo plastic tuning phases, termed “critical periods”; “critical” because disturbances during these phases can lead to lasting changes in […]

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