A multi-institutional investigation of psilocybin’s effects on mouse behavior

Kavli Affiliate: Vikaas Sohal and Mazen Kheirbek | Authors: Odilia D Lu, Katrina White, Kendall Raymond, Christine Liu, Alexandra S Klein, Nathaniel Green, Sam Vaillancourt, Austin Gallagher, Lena Shindy, Alyssa Li, Ruoxian Li, Mila Zou, Kira Wallquist, Austen B Casey, Lindsay P Cameron, Matthew B Pomrenze, Vikaas Sohal, Mazen A Kheirbek, Andrea M Gomez, Stephan […]


Continue.. A multi-institutional investigation of psilocybin’s effects on mouse behavior

COSMOS-Web: Unraveling the Evolution of Galaxy Size and Related Properties at $2<z<10$

Kavli Affiliate: John D. Silverman | First 5 Authors: Lilan Yang, Jeyhan S. Kartaltepe, Maximilien Franco, Xuheng Ding, Mark J. Achenbach | Summary: We measure galaxy sizes from $2 < z < 10$ using COSMOS-Web, the largest-area JWST imaging survey to date, covering $sim$0.54 deg$^2$. We analyze the rest-frame optical (~5000A) size evolution and its […]


Continue.. COSMOS-Web: Unraveling the Evolution of Galaxy Size and Related Properties at $2<z<10$

Discovery of extreme Quasi-Periodic Eruptions in a newly accreting massive black hole

Kavli Affiliate: Erin Kara | First 5 Authors: Lorena Hernández-García, Joheen Chakraborty, Paula Sánchez-Sáez, Claudio Ricci, Jorge Cuadra | Summary: Quasi-periodic eruptions (QPEs) are rapid, recurring X-ray bursts from supermassive black holes, believed to result from interactions between accretion disks and surrounding matter. The galaxy SDSS1335+0728, previously stable for two decades, exhibited an increase in […]


Continue.. Discovery of extreme Quasi-Periodic Eruptions in a newly accreting massive black hole

Rapidly varying ionization features in a Quasi-periodic Eruption: a homologous expansion model for the spectroscopic evolution

Kavli Affiliate: Erin Kara | First 5 Authors: Joheen Chakraborty, Peter Kosec, Erin Kara, Giovanni Miniutti, Riccardo Arcodia | Summary: Quasi-Periodic Eruptions (QPEs) are recurring bursts of soft X-ray emission from supermassive black holes (SMBHs), which a growing class of models explains via extreme mass-ratio inspirals (EMRIs). QPEs exhibit blackbody-like emission with significant temperature evolution, […]


Continue.. Rapidly varying ionization features in a Quasi-periodic Eruption: a homologous expansion model for the spectroscopic evolution

Discovery of extreme Quasi-Periodic Eruptions in a newly accreting massive black hole

Kavli Affiliate: Claudio Ricci | First 5 Authors: Lorena Hernández-García, Joheen Chakraborty, Paula Sánchez-Sáez, Claudio Ricci, Jorge Cuadra | Summary: Quasi-periodic eruptions (QPEs) are rapid, recurring X-ray bursts from supermassive black holes, believed to result from interactions between accretion disks and surrounding matter. The galaxy SDSS1335+0728, previously stable for two decades, exhibited an increase in […]


Continue.. Discovery of extreme Quasi-Periodic Eruptions in a newly accreting massive black hole

TOI-6478 b: a cold under-dense Neptune transiting a fully convective M dwarf from the thick disc

Kavli Affiliate: Avi Shporer | First 5 Authors: Madison G. Scott, Amaury H. M. J. Triaud, Khalid Barkaoui, Daniel Sebastian, Adam J. Burgasser | Summary: Growing numbers of exoplanet detections continue to reveal the diverse nature of planetary systems. Planet formation around late-type M dwarfs is of particular interest. These systems provide practical laboratories to […]


Continue.. TOI-6478 b: a cold under-dense Neptune transiting a fully convective M dwarf from the thick disc

Open-source Photobleacher for Fluorescent Imaging of Large Pigment-Rich Tissues

Kavli Affiliate: Nathaniel Heintz | Authors: Tatsuya C. Murakami, Nick Belenko, Griffin Dennis, Cuidong Wang, Maria Esterlita Siantoputri, Yurie Maeda, Christina Pressl and Nathaniel Heintz | Summary: Fluorescent imaging enables visualization of the specific molecules of interest with high contrast, and the use of multiple fluorophores in a single tissue sample allows visualization of complex […]


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TUCL-Seq for miRNA single molecule sequencing

Kavli Affiliate: Li Zhao | Authors: Jicai Fan, Zhao Li, Xuejiao You, Lei Liu, Huan Jin, Ping Wu, Yushan Han, Lei Sun, Pengwei Xu, Yongfeng Liu, Jianjun Luo and Qin Yan | Summary: MicroRNAs (miRNAs) are pivotal regulatory molecules in gene expression, and their precise quantification is essential for elucidating their roles in diverse biological […]


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MACER3D — an upgrade of MACER2D with enhanced subgrid models and gas physics — and its application to simulating AGN feedback in a massive elliptical galaxy

Kavli Affiliate: Feng Yuan | First 5 Authors: Haoen Zhang, Haojie Xia, Suoqing Ji, Feng Yuan, Minhang Guo | Summary: We present MACER3D (Multiscale AGN-regulated Cosmic Ecosystem Resolver in 3D), a new suite of three-dimensional hydrodynamic simulations that study active galactic nuclei (AGN) feedback on galactic scales over Gyr duration, with major enhancement in subgrid […]


Continue.. MACER3D — an upgrade of MACER2D with enhanced subgrid models and gas physics — and its application to simulating AGN feedback in a massive elliptical galaxy

Autism-associated Scn2a haploinsufficiency disrupts in vivo dendritic signaling and impairs flexible decision-making

Kavli Affiliate: Kevin Bender | Authors: Hao Wu, Luqun Shen, Jonathan Indajang, Neil K Savalia, Timothy G Johnson, Jiayin Qu, Kevin J Bender and Alex C Kwan | Summary: SCN2A is a high-confidence risk gene for autism spectrum disorder. Loss-of-function mutations in Scn2a reduce dendritic excitability in neocortical pyramidal cells. However, the impact of Scn2a […]


Continue.. Autism-associated Scn2a haploinsufficiency disrupts in vivo dendritic signaling and impairs flexible decision-making