Two types of locus coeruleus norepinephrine neurons drive reinforcement learning

Kavli Affiliate: Jeremiah Cohen | Authors: Zhixiao Su and Jeremiah Y. Cohen | Summary: Abstract The cerebral cortex generates flexible behavior by learning. Reinforcement learning is thought to be driven by error signals in midbrain dopamine neurons. However, they project more densely to basal ganglia than cortex, leaving open the possibility of another source of […]


Continue.. Two types of locus coeruleus norepinephrine neurons drive reinforcement learning

Visuomotor interactions in the mouse forebrain mediated by extrastriate cortico-cortical pathways

Kavli Affiliate: Menno Witter, Jonathan Whitlock | Authors: Karoline Hovde, Ida V. Rautio, Andrea Marie Hegstad, Menno P. Witter and Jonathan R. Whitlock | Summary: Abstract The mammalian visual system can be broadly divided into two functional processing pathways: a dorsal stream supporting visually and spatially guided actions, and a ventral stream enabling object recognition. […]


Continue.. Visuomotor interactions in the mouse forebrain mediated by extrastriate cortico-cortical pathways

Adult born hippocampal granule cells promote pattern separation by bidirectionally modulating the remapping of place and cue cells

Kavli Affiliate: Rene Hen | Authors: Sebnem N. Tuncdemir, Andres D. Grosmark, Hannah Chung, Victor M. Luna, Clay O. Lacefield, Attila Losonczy and Rene Hen | Summary: Abstract The hippocampal dentate gyrus (DG) exhibits a unique form of neural plasticity that results from continuous integration of adult born neurons, referred to as ‘adult neurogenesis’. Recent […]


Continue.. Adult born hippocampal granule cells promote pattern separation by bidirectionally modulating the remapping of place and cue cells

Directional detection of dark matter with anisotropic response functions

Kavli Affiliate: Noah Kurinsky | First 5 Authors: Christian Boyd, Yonit Hochberg, Yonatan Kahn, Eric David Kramer, Noah Kurinsky | Summary: Direct detection for sub-GeV dark matter is developing rapidly, with many novel experimental ideas and theoretical methods emerging. In this work, we extend the dielectric formalism for dark matter scattering to incorporate anisotropic material […]


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Dual electro-optic frequency comb photonic thermometry

Kavli Affiliate: Zeeshan Ahmed | First 5 Authors: Adam J. Fleisher, Zeeshan Ahmed, Tobias Herman, Matthew R. Hartings, | Summary: We report a precision realization of photonic thermometry using dual-comb spectroscopy to interrogate a $pi$-phase-shifted fiber Bragg grating. We achieve read-out stability of 7.5 mK at 1 s and resolve temperature changes of similar magnitude–sufficient […]


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Engineered retrovirus-like Arc extracellular vesicles for the in vivo targeted delivery of mRNA into the brain

Kavli Affiliate: Robert Hawkins | Authors: Wenchao Gu, Sijin Luozhong, Ketaki Londhe, Nadine Elkasri, Simian Cai, Robert Hawkins, Zhefan Yuan, Kai Su-Greene, Margaret Cruz, Yu-Wei Chang, Patrick McMullen, Chunyan Wu, Changwoo Seo, Akash Guru, Wenting Gao, Tara Sarmiento, Chris Schaffer, Nozomi Nishimura, Richard Cerione, Melissa Warden, Robert Langer and Shaoyi Jiang | Summary: Abstract Systemic […]


Continue.. Engineered retrovirus-like Arc extracellular vesicles for the in vivo targeted delivery of mRNA into the brain

Visualizing and manipulating chiral interface states in a moiré quantum anomalous Hall insulator

Kavli Affiliate: Michael F. Crommie | First 5 Authors: Canxun Zhang, Tiancong Zhu, Salman Kahn, Tomohiro Soejima, Kenji Watanabe | Summary: Moir’e systems made from stacked two-dimensional materials host novel correlated and topological states that can be electrically controlled via applied gate voltages. We have used this technique to manipulate Chern domains in an interaction-driven […]


Continue.. Visualizing and manipulating chiral interface states in a moiré quantum anomalous Hall insulator

Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins (RAMPs)

Kavli Affiliate: Thomas P. Sakmar | Authors: Ilana B. Kotliar, Emilie Ceraudo, Kevin Kemelmakher-Liben, Deena A. Oren, Emily Lorenzen, Tea Dodig-Crnković, Mizuho Horioka-Duplix, Thomas Huber, Jochen M. Schwenk and Thomas P. Sakmar | Summary: Abstract Cholestatic itch is a severe and debilitating symptom in liver diseases with limited treatment options. The class A G protein-coupled […]


Continue.. Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins (RAMPs)

Search for an invisible $Z^prime$ in a final state with two muons and missing energy at Belle II

Kavli Affiliate: T. Higuchi | First 5 Authors: Belle II Collaboration, I. Adachi, K. Adamczyk, L. Aggarwal, H. Ahmed | Summary: The $L_{mu}-L_{tau}$ extension of the standard model predicts the existence of a lepton-flavor-universality-violating $Z^{prime}$ boson that couples only to the heavier lepton families. We search for such a $Z^prime$ through its invisible decay in […]


Continue.. Search for an invisible $Z^prime$ in a final state with two muons and missing energy at Belle II

Non-Abelian effects in dissipative photonic topological lattices

Kavli Affiliate: Alireza Marandi | First 5 Authors: Midya Parto, Christian Leefmans, James Williams, Franco Nori, Alireza Marandi | Summary: Topology is central to phenomena that arise in a variety of fields, ranging from quantum field theory to quantum information science to condensed matter physics. Recently, the study of topology has been extended to open […]


Continue.. Non-Abelian effects in dissipative photonic topological lattices