Clover-like object vector representations support human spatial cognition

Kavli Affiliate: Jonathan Whitlock | Authors: Marcia Becu, Ivan Markel Krasovec, Pearl Saldanha, Jonathan Whitlock and Christian F Doeller | Summary: Vector-based spatial coding has been demonstrated in rodents, yet its neural basis in humans and its contribution to navigation remain poorly understood. Using a novel spatial updating task, we show that egocentric directional signals […]


Continue.. Clover-like object vector representations support human spatial cognition

Age-related Increase in Locus Coeruleus Activity and Connectivity with Prefrontal Cortex during Ambiguity Processing

Kavli Affiliate: Maryam Ziaei | Authors: Arjun Dave, Shuer Ye, Leona R Batz, Xiaqing Lan, Heidi Jacobs and Maryam Ziaei | Summary: Interpreting ambiguous environmental cues, like facial expressions, becomes increasingly challenging with age, especially as cognitive resources decline. Managing these challenges requires adaptive neural mechanisms that are essential for maintaining mental well-being. The locus […]


Continue.. Age-related Increase in Locus Coeruleus Activity and Connectivity with Prefrontal Cortex during Ambiguity Processing

Frontoparietal functional dedifferentiation during naturalistic movie watching among older adults at risk of emotional vulnerability

Kavli Affiliate: Maryam Ziaei | Authors: Shuer Ye, Arjun Dave, Alireza Salami and Maryam Ziaei | Summary: Functional dedifferentiation, a hallmark of brain aging particularly evident within the frontoparietal network (FPN), has been extensively investigated in the context of cognitive decline, yet its implications for late-life mental health remain poorly understood. Leveraging naturalistic fMRI combined […]


Continue.. Frontoparietal functional dedifferentiation during naturalistic movie watching among older adults at risk of emotional vulnerability

Differences in Cajal-Retzius cell density and postnatal persistence across cortical areas revealed by a novel intersectional genetic labeling approach

Kavli Affiliate: Giulia Quattrocolo | Authors: Kristian Moan, Robert P Machold and Giulia Quattrocolo | Summary: Cajal-Retzius (CR) cells are glutamatergic neurons that transiently populate the most superficial layer of the isocortex and allocortex during development, serving an essential role during both prenatal and early postnatal brain development. Notably, these cells disappear from most cortical […]


Continue.. Differences in Cajal-Retzius cell density and postnatal persistence across cortical areas revealed by a novel intersectional genetic labeling approach

Topographically organized dorsal raphe activity modulates forebrain sensory-motor computations and adaptive behaviors.

Kavli Affiliate: Emre Yaksi | Authors: Aytac Kadir Mutlu, Bram Serneels, Christoph Wiest, Anh-Tuan Trinh, Ricarda Bardenhewer, Fabrizio Palumbo, Oda Bjornevik Frisvold, Inger Kristine Fjeldskaar Aukrus, Anna Maria Ostenrath and Emre Yaksi | Summary: The dorsal raphe nucleus (DRN) plays an important role in shaping a wide range of behaviors, including mood, motivation, appetite, sleep, […]


Continue.. Topographically organized dorsal raphe activity modulates forebrain sensory-motor computations and adaptive behaviors.

Dorsal-caudal and ventral hippocampus target different cell populations in the medial frontal cortex in rodents

Kavli Affiliate: Menno Witter | Authors: Paola Alemán-Andrade, Menno P. Witter, Ken-Ichiro Tsutsui and Shinya Ohara | Summary: Direct projections from the ventral hippocampus (vHPC) to the medial frontal cortex (MFC) play crucial roles in memory and emotional regulation. Using anterograde transsynaptic tracing and in vitro electrophysiology in mice, we document a previously unexplored pathway […]


Continue.. Dorsal-caudal and ventral hippocampus target different cell populations in the medial frontal cortex in rodents

Inhibition mediated by group III mGluRs regulates habenula activity and defensive behaviors

Kavli Affiliate: Emre Yaksi | Authors: Anna Maria Ostenrath, Nicholas Faturos, Yagnur Isik Ciftci Cobanoglu, Bram Serneels, Inyoung Jeong, Anja Enz, Francisca Hinrichsen, Aytac Kadir Mutlu, Ricarda Bardenhewer, Suresh Kumar Jetti, Stephan C. F. Neuhauss, Nathalie Jurisch-Yaksi and Emre Yaksi | Summary: Inhibition contributes to various brain computations from sensory motor transformations to cognitive operations. […]


Continue.. Inhibition mediated by group III mGluRs regulates habenula activity and defensive behaviors

Single neurons and networks in the claustrum integrate input from widespread cortical sources

Kavli Affiliate: Clifford Kentros, Menno Witter | Authors: Andrew M Shelton, David K Oliver, Joachim S Grimstvedt, Ivan P Lazarte, Ishaan Kapoor, Jake A Swann, Caitlin A Ashcroft, Simon N Williams, Niall Conway, Amy Robinson, Clifford G Kentros, Menno P Witter, Simon JB Butt and Adam M Packer | Summary: The claustrum is highly interconnected […]


Continue.. Single neurons and networks in the claustrum integrate input from widespread cortical sources

Event structure sculpts neural population dynamics in the lateral entorhinal cortex

Kavli Affiliate: Edvard Moser and May-Britt Moser | Authors: Benjamin R Kanter, Christine M Lykken, May-Britt Moser and Edvard I. Moser | Summary: Our experience of the world is a continuous stream of events which must be segmented and organized simultaneously at multiple timescales. The neural mechanisms underlying this process remain unknown. Here, we simultaneously […]


Continue.. Event structure sculpts neural population dynamics in the lateral entorhinal cortex

Left-right-alternating theta sweeps in the entorhinal-hippocampal spatial map

Kavli Affiliate: Edvard Moser and May-Britt Moser | Authors: Abraham Z. Vollan, Richard J. Gardner, May-Britt Moser and Edvard I. Moser | Summary: Place cells in the hippocampus and grid cells in the entorhinal cortex are elements of a neural map of self- position. To benefit navigation, this representation must be dynamically related to surrounding […]


Continue.. Left-right-alternating theta sweeps in the entorhinal-hippocampal spatial map