Kavli Affiliate: Yifan Cheng | Authors: Hayden S Saunders, Un Seng Chio, Camille M Moore, Vijay Ramani, Yifan Cheng and Geeta Narlikar | Summary: Summary: The essential architectural protein HMGB1 increases accessibility of nucleosomal DNA and counteracts the effects of linker histone H1. However, HMGB1 is less abundant than H1 and binds nucleosomes more weakly […]
Kavli Affiliate: John Reynolds | Authors: Helen R P Phillips, George Gardner Brown, Sam W. James, Jérôme Mathieu, John Warren Reynolds, Maheshi E Dharmasiri, Claire L. Singer, Maria J. I. Briones, Heather C. Procter and Erin K. Cameron | Summary: Summary: Earthworms (Annelida: Clitellata: Crassiclitellata) are prominent members of the soil community, important to many […]
Kavli Affiliate: Denis Wirtz | Authors: Yufei Wu, Pei-Hsun Wu, Allison Chambliss, Denis Wirtz and Sean Sun | Summary: Summary: Biological systems are complex networks involving tens of thousands of interacting molecular components, and measurable biological functions are emerging properties of these complex networks. Many quantitative studies in biology attempt to connect biological function with […]
Kavli Affiliate: Clifford Kentros, Menno Witter | Authors: Andrew M Shelton, David K Oliver, Joachim S Grimstvedt, Ivan P Lazarte, Ishaan Kapoor, Jake A Swann, Caitlin A Ashcroft, Simon N Williams, Niall Conway, Amy Robinson, Clifford G Kentros, Menno P Witter, Simon JB Butt and Adam M Packer | Summary: The claustrum is highly interconnected […]
Kavli Affiliate: Damon Clark | Authors: Garrett Sager, Fabian Cole Pallasdies, Robert Gowers, Snusha Ravikumar, Elizabeth Wu, Daniel Colon-Ramos, Susanne Schreiber and Damon A Clark | Summary: Summary: Neuronal function depends critically on the cell biological organization of mitochondria, which regulate calcium signals and produce energy, among other roles. However, little is known about how […]
Kavli Affiliate: Jyoti Mishra and Dhakshin Ramanathan | Authors: Morteza Salimi, Milad Nazari, Jonathan Mishler, Jyoti Mishra and Dhakshin Ramanathan | Summary: Summary: Theta burst stimulation (TBS), an FDA-cleared treatment for depression, is hypothesized to modulate excitability in the prefrontal cortex, though this has not definitively been shown in vivo. We performed calcium imaging on […]
Kavli Affiliate: Xiaoqin Wang | Authors: Chaoqun Cheng, Zijian Huang, Ruiming Zhang, Guozheng Huang, Han Wang, Likai Tang and Xiaoqin Wang | Summary: Summary: The ability to track positions and poses (body parts) of multiple monkeys in a 3D space in real time is highly desired by non-human primate (NHP) researchers in behavioral and systems […]
Kavli Affiliate: David Linden | Authors: Patrick R Cooke and David J Linden | Summary: Summary: It is widely believed that axons in the central nervous system of adult mammals do not regrow following injury. This failure is thought, at least in part, to underlie the limited recovery of function following injury to the brain […]
Kavli Affiliate: Jean Fan and Laurent Younes | Authors: Lanlan Ji, An Wang, Shreyash Sonthalia, Daniel Q Naiman, Laurent Younes, Carlo Colantuoni and Donald Geman | Summary: Summary: Definition of cell classes across the tissues of living organisms is central in the analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across biomedicine. Marker […]
Kavli Affiliate: Donald Geman and Laurent Younes | Authors: Lanlan Ji, An Wang, Shreyash Sonthalia, Daniel Q Naiman, Laurent Younes, Carlo Colantuoni and Donald Geman | Summary: Accurate identification of cell classes across the tissues of living organisms is central in the analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across biomedicine. Such […]