Recurrent Connectivity Shapes Spatial Coding in Hippocampal CA3 Subregions

Kavli Affiliate: Darcy Peterka and Attila Losonczy | Authors: Eunji Kong, Erfan Zabeh, Zhenrui Liao, Tiberiu S. Mihaila, Darcy S. Peterka, Caroline Wilson, Charan Santhirasegaran, Attila Losonczy and Tristan Geiller | Summary: Stable and flexible neural representations of space in the hippocampus are crucial for navigating complex environments. However, how these distinct representations emerge from […]


Continue.. Recurrent Connectivity Shapes Spatial Coding in Hippocampal CA3 Subregions

Single Objective Light Sheet Microscopy allows high-resolution in vivo brain imaging of Drosophila

Kavli Affiliate: Mark Ellisman | Authors: Francisco Joaquín Tassara, Mariano Barella, Lourdes Simó, Mailen Folgueira, Micaela Rodríguez-Caron, Juan Ignacio Ispizua, Mark H. Ellisman, Horacio O. de la Iglesia, M. Fernanda Ceriani and Julián Gargiulo | Summary: In vivo imaging of dynamic sub-cellular brain structures in Drosophila melanogaster is key to understanding several phenomena in neuroscience. […]


Continue.. Single Objective Light Sheet Microscopy allows high-resolution in vivo brain imaging of Drosophila

Electrical Coordinated Reset Stimulation Induces Network Desynchronization in an in Vivo Model of Status Epilepticus

Kavli Affiliate: Sridevi Sarma | Authors: Daniel Ehrens, Fadi Aeed, Yara Otor, Vivek Charu, Babak Razavi, Sridevi V Sarma, Yitzhak Schiller and Peter A Tass | Summary: Epilepsy, a neurological disorder characterized by recurrent seizures, profoundly impacts individuals worldwide. Various electrical stimulation protocols have been investigated to mitigate epileptic seizures, among which Coordinated Reset (CR) […]


Continue.. Electrical Coordinated Reset Stimulation Induces Network Desynchronization in an in Vivo Model of Status Epilepticus

Resting-state connectivity modifies the effects of amyloid on cognitive and physical function: evidence for network-based cognitive reserve

Kavli Affiliate: Michael Miller | Authors: Paul J Laurienti, Stephen B Kritchevsky, Robert G Lyday, Michael E Miller, Samuel N Lockhart, Melissa M Rundle, Christina E Hugenschmidt, Jonathan H Burdette, Heather M Shappell, Haiying Chen, Laura D Baker, Blake R Neyland and Roee Holtzer | Summary: Cognitive and physical function are interrelated in aging co-occurring […]


Continue.. Resting-state connectivity modifies the effects of amyloid on cognitive and physical function: evidence for network-based cognitive reserve

A green lifetime biosensor for calcium that remains bright over its full dynamic range

Kavli Affiliate: Gaby Maimon | Authors: Franka H. van der Linden, Stephen C. Thornquist, Rick M. ter Beek, Jelle Y. Huijts, Mark A. Hink, Theodorus W.J. Gadella, Jr., Gaby Maimon and Joachim Goedhart | Summary: Fluorescent biosensors toggle between two states and for the vast majority of biosensors one state is bright and the other […]


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Dynamic modulation of social gaze by sex and familiarity in marmoset dyads

Kavli Affiliate: Anirvan Nandy | Authors: Feng Xing, Alec Graham Sheffield, Monika P. Jadi, Steve W. C. Chang and Anirvan S. Nandy | Summary: Social communication relies on the ability to perceive and interpret the direction of others’ attention, and is commonly conveyed through head orientation and gaze direction in humans and nonhuman primates. However, […]


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Molecular impact of nicotine and smoking exposure on the developing and adult mouse brain

Kavli Affiliate: Keri Martinowich | Authors: Daianna Gonzalez-Padilla, Nicholas J. Eagles, Marisol Cano, Geo Pertea, Andrew E. Jaffe, Kristen R. Maynard, Dana B. Hancock, James T. Handa, Keri Martinowich and Leonardo Collado-Torres | Summary: Maternal smoking during pregnancy (MSDP) is associated with significant cognitive and behavioral effects on offspring. While neurodevelopmental outcomes have been studied […]


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xIV-LDDMM Toolkit: A Suite of Image-Varifold Based Technologies for Representing and Mapping 3D Imaging and Spatial-omics Data Simultaneously Across Scales

Kavli Affiliate: Laurent Younes and Michael Miller | Authors: Kaitlin Stouffer, Xiaoyin Chen, Hongkui Zeng, Benjamin Charlier, Laurent Younes, Alain Trouve and Michael I Miller | Summary: Advancements in imaging and molecular techniques enable the collection of subcellular-scale data. Diversity in measured features, resolution, and physical scope of capture across technologies and experimental protocols pose […]


Continue.. xIV-LDDMM Toolkit: A Suite of Image-Varifold Based Technologies for Representing and Mapping 3D Imaging and Spatial-omics Data Simultaneously Across Scales

A consensus definition for deep layer 6 excitatory neurons in mouse neocortex

Kavli Affiliate: Solange Brown, Loyal Goff, and Patrick Kanold | Authors: Su-Jeong Kim, Travis A. Babola, Kihwan Lee, Chanel J. Matney, Alina C. Spiegel, Michael H. Liew, Eva M. Schulteis, Austin E. Coye, Mikhail Proskurin, Hyunwook Kang, Julia A. Kim, Maxime Chevee, Kiwoong Lee, Patrick O. Kanold, Loyal A. Goff, Juhyun Kim and Solange P […]


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Defective glycosylation and ELFN1 binding of mGluR6 congenital stationary night blindness mutants

Kavli Affiliate: Michael Miller | Authors: Mustansir Pindwarawala, Faiyaz A. K. Abid, Jaeeun Lee, Michael L. Miller, Juliet S. Noppers, Andrew P. Rideout and Melina A. Agosto | Summary: Summary: Synaptic transmission from photoreceptors to ON-bipolar cells (BCs) requires the postsynaptic metabotropic glutamate receptor mGluR6, located at BC dendritic tips. Binding of the neurotransmitter glutamate […]


Continue.. Defective glycosylation and ELFN1 binding of mGluR6 congenital stationary night blindness mutants