HP1B and H3K9me3 Regulate Olfactory Receptor Choice and Transcriptional Identity

Posted by dbos UCSF

Kavli Affiliate: Daniele Canzio and Stavros Lomvardas | Authors: Martin Escamilla-del-Arenal, Rachel Duffie, Hani Shayya, Valentina Loconte, Axel Ekman, Lena Annika Street, Adan Horta, Daniele Canzio, Kevin Monahan, Carolyn A Larabell, Marko Jovanovic and Stavros Lomvardas/p> | Summary: Diverse epigenetic regulatory mechanisms ensure and regulate cellular diversity. Among others, the histone 3 lysine 9 me3 […]


Continue.. HP1B and H3K9me3 Regulate Olfactory Receptor Choice and Transcriptional Identity

Rapid rebalancing of co-tuned ensemble activity in the auditory cortex

Posted by dbos Hopkins

Kavli Affiliate: Patrick Kanold | Authors: HiJee Kang, Travis Babola and Patrick O Kanold | Summary: Sensory information is represented by small neuronal ensembles in sensory cortices. Neuronal activity shows high trial-by-trial variability in that repeated presentation of the same stimulus, e. g., multiple presentations of the same sound activate differing ensembles in the auditory […]


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Deep Learning Improves Parameter Estimation in Reinforcement Learning Models

Posted by dbos UCSD / Salk

Kavli Affiliate: Marcelo Mattar | Authors: Hua-Dong Xiong, Li Ji-An, Marcelo G Mattar and Robert C Wilson | Summary: Cognitive models are widely used in psychology and neuroscience to formulate and test hypotheses about cognitive processes. These processes are characterized by model parameters, which are then used for scientific inference. The reliability of scientific conclusions […]


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Neural representation of action symbols in primate frontal cortex

Posted by dbos Rockefeller

Kavli Affiliate: Winrich Freiwald | Authors: Lucas Y Tian, Kedar U Garzón, Daniel J. Hanuska, Adam G Rouse, Mark AG Eldridge, Marc H Schieber, Xiao-Jing Wang, Joshua B Tenenbaum and Winrich A Freiwald | Summary: At the core of intelligence lies proficiency in solving new problems, including those that differ dramatically from problems seen before. […]


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Bridging model and experiment in systems neuroscience with Cleo: the Closed-Loop, Electrophysiology, and Optophysiology simulation testbed

Posted by dbos Hopkins

Kavli Affiliate: Adam S. Charles | Authors: Kyle A. Johnsen, Nathanael A. Cruzado, Zachary C. Menard, Adam A. Willats, Adam S. Charles, Jeffrey E. Markowitz and Christopher J. Rozell | Summary: Systems neuroscience has experienced an explosion of new tools for reading and writing neural activity, enabling exciting new experiments such as all-optical or closed-loop […]


Continue.. Bridging model and experiment in systems neuroscience with Cleo: the Closed-Loop, Electrophysiology, and Optophysiology simulation testbed

3D map-guided modeling of functional endometrial tissue using multi-compartment assembloids

Posted by dbos Hopkins

Kavli Affiliate: Denis Wirtz | KEHAN REN, VICTORIA DUARTE, XIN DI ZHOU, BRYAN HO, ANDRE FORJAZ, ASHLEIGH CRAWFORD, GRETCHEN M ALICEA-REBECCA, SAURABH JOSHI, PRAFUL R NAIR, EBAN A HANNA and DENIS WIRTZ | Summary: The human endometrium is a dynamic tissue that lines the uterus and undergoes constant remodeling, making it especially susceptible to gynecological […]


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Strain variation identifies a neural substrate for behavioral evolution in Drosophila

Posted by dbos Rockefeller

Kavli Affiliate: Vanessa Ruta | Anna Ryba, Philipp Brand, Rory T. Coleman, Yarden Greenfeld, Yael N. Tsitohay, Florian Hollunder, Katharine Keller, Murtaza Hathiyari, Tianyi Wei, Paolo Emilio Barbano and Vanessa Ruta | Summary: Sexual selection acts on heritable differences within species, driving the parallel diversification of signal production in one sex and behavioral responses in […]


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Towards individualized deep brain stimulation: A stereoencephalography-based workflow for unbiased neurostimulation target identification

Posted by dbos UCSF

Kavli Affiliate: Edward Chang | Authors: Jeremy Saal, Kelly Kadlec, Anusha B. Allawala, Lucille Johnston, Ryan Leriche, Ritwik Vatsyayan, Yiyuan Han, Audrey Kist, Tommaso Di Ianni, Heather E. Dawes, Edward F. Chang, A Moses Lee, Andrew D. Krystal, Khaled Moussawi, Prasad Shirvalkar and Kristin K. Sellers | Summary: Background: Deep-brain stimulation (DBS) is increasingly being […]


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Artificial Intelligence-driven Whole-brain Cell Mapping with Highly Multiplexed In Situ Hybridization

Posted by dbos Rockefeller

Kavli Affiliate: Nathaniel Heintz | Authors: Tatsuya Murakami, Meng Xia, Yurie Maeda, Yuejia Yin, Paolo Emilio Barbano, Ziyi Lin, Tomoyuki Mano, Kazuki Tainaka, Sam Reiter and Nathaniel Heintz | Summary: Recent advances in three-dimensional single-cell-resolution imaging have begun to link organ-wide and cellular level research in development and disease research. Harnessing the power of whole-mount […]


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Tactile responses in the mouse perirhinal cortex show invariance to physical features of the stimulus

Posted by dbos NTNU

Kavli Affiliate: Maximiliano Jose Nigro | Rejwan Hamza Farhad Salih, Luis Fernando Cobar, Francois Philippe Pauzin, Davide Zoccolan and Maximiliano Jose Nigr | Summary: Abstract Sensory processing in the cortex follows a hierarchical structure, transforming fine-grained stimulus features into abstract, invariant representations. These transformations have typically been characterised in visual pathways ranging from primary visual […]


Continue.. Tactile responses in the mouse perirhinal cortex show invariance to physical features of the stimulus