Kavli Affiliate: Li Zhao | Authors: Li Ya Zhao, Jing Shi, Zhao Yang Xu, Jia Lin Sun, Zhang Yuan Yan, Zhi Wu Tong, Ren Xiang Tan, Rui Hua Jiao and Hui Ming Ge | Summary: Bacterial aromatic polyketides are compounds with multiple aromatic rings synthesized by bacterial type II polyketide synthases (PKSs), some of which […]
Kavli Affiliate: Hana El-Samad | Authors: Zara Y. Weinberg, Sarah S. Soliman, Matthew S. Kim, Irene P. Chen, Melanie Ott and Hana El-Samad | Summary: Synthetic and chimeric receptors capable of recognizing and responding to user-defined antigens have enabled “smart” therapeutics based on engineered cells. These cell engineering tools depend on antigen sensors which are […]
Kavli Affiliate: Martin Lindquist | Authors: Maria Papadaki, Eleftherios Pavlos, Marc Dubourdeau, Vincent Bailif, Kamal Badirou, Ioanna-Evdokia Galani, Dimitris Papelis, Natalia Kamperi, Vasiliki Triantafyllia, Lena Siouti, Maria Salagianni, Maria Manioudaki, Nikolaos Paschalidis, Giannis Vatsellas, Evangelia Koukaki, Vasiliki Rapti, Dimitris Thanos, Nikoletta Rovina, Garyfallia Poulakou, Aurelie Cobat, Jean-Laurent Casanova, Constantin Tamvakopoulos and Evangelos Andreakos | Summary: […]
Kavli Affiliate: Martin Lindquist | Authors: Farzad V. Farahani, Mary Beth Nebel, Tor Wager and Martin A. Lindquist | Summary: Recent gains in functional magnetic resonance imaging (fMRI) studies have been driven by increasingly sophisticated statistical and computational techniques and the ability to capture brain data at finer spatial and temporal resolution. These advances allow […]
Kavli Affiliate: Li Zhao | Authors: Xin Hou, Yong He, Pan Fang, Shi-Qiang Mei, Zan Xu, Wei-Chen Wu, Jun-Hua Tian, Shun Zhang, Zhen-Yu Zeng, Qin-Yu Gou, Gen-Yang Xin, Shi-Jia Le, Yin-Yue Xia, Yu-Lan Zhou, Feng-Ming Hui, Yuan-Fei Pan, John-Sebastian Eden, Zhao-Hui Yang, Chong Han, Yue-Long Shu, Deyin Guo, Jun Li, Edward C Holmes, Zhao-Rong Li […]
Kavli Affiliate: Yifan Cheng | Authors: Hayden S Saunders, Un Seng Chio, Camille M Moore, Vijay Ramani, Yifan Cheng and Geeta Narlikar | Summary: Summary: The essential architectural protein HMGB1 increases accessibility of nucleosomal DNA and counteracts the effects of linker histone H1. However, HMGB1 is less abundant than H1 and binds nucleosomes more weakly […]
Kavli Affiliate: John Reynolds | Authors: Helen R P Phillips, George Gardner Brown, Sam W. James, Jérôme Mathieu, John Warren Reynolds, Maheshi E Dharmasiri, Claire L. Singer, Maria J. I. Briones, Heather C. Procter and Erin K. Cameron | Summary: Summary: Earthworms (Annelida: Clitellata: Crassiclitellata) are prominent members of the soil community, important to many […]
Kavli Affiliate: Denis Wirtz | Authors: Yufei Wu, Pei-Hsun Wu, Allison Chambliss, Denis Wirtz and Sean Sun | Summary: Summary: Biological systems are complex networks involving tens of thousands of interacting molecular components, and measurable biological functions are emerging properties of these complex networks. Many quantitative studies in biology attempt to connect biological function with […]
Kavli Affiliate: Clifford Kentros, Menno Witter | Authors: Andrew M Shelton, David K Oliver, Joachim S Grimstvedt, Ivan P Lazarte, Ishaan Kapoor, Jake A Swann, Caitlin A Ashcroft, Simon N Williams, Niall Conway, Amy Robinson, Clifford G Kentros, Menno P Witter, Simon JB Butt and Adam M Packer | Summary: The claustrum is highly interconnected […]
Kavli Affiliate: Damon Clark | Authors: Garrett Sager, Fabian Cole Pallasdies, Robert Gowers, Snusha Ravikumar, Elizabeth Wu, Daniel Colon-Ramos, Susanne Schreiber and Damon A Clark | Summary: Summary: Neuronal function depends critically on the cell biological organization of mitochondria, which regulate calcium signals and produce energy, among other roles. However, little is known about how […]