Kavli Affiliate: Noelle L’Etoile | Authors: Zhijian Ji, Bingying Wang, Junqiang Liu, Rashmi K. Chandra, Winnie Yang, Yong Long, Michael Egan, Noelle L’Etoile and Dengke K. Ma | Summary: Visible light influences a range of physiological processes, yet how animals respond to it independently of the visual system remains largely unknown. Here, we uncover a […]
Kavli Affiliate: Joshua Vogelstein | Authors: Tingshan Liu, Jayanta Dey, Beiya Xu, Samuel S Alldritt, Karl-Heinz Nenning, Kyoungseob Byeon, Ting Xu and Joshua T. Vogelstein | Summary: Sex classification using neuroimaging data has the potential to revolutionize personalized diagnostics by revealing subtle structural brain differences that underlie sex-specific disease risks. Despite the promise of machine […]
Kavli Affiliate: Justus M Kebschull | Authors: Hyopil Kim, Cheng Xu, Craig Washington, Maggie Lowman and Justus M Kebschull | Summary: Brain-wide neural circuits are formed by the diverse axonal branching patterns of many individual neurons. Here we introduce POlNTseq (projections of interest by sequencing), a high-throughput and user-friendly barcoded connectomics method that uses cell […]
Kavli Affiliate: Richard Huganir | Authors: Hana Goldschmidt Merrion, Casey N. Barber, Santosh S. Renuse, Jevon Cutler, Simion Kreimer, Alexei M. Bygrave, David J. Meyers, William Dylan Hale, Akhilesh Pandey and Richard L. Huganir | Summary: Synaptic plasticity in the central nervous system enables the encoding, storing, and integrating new information. AMPA-type glutamate receptors (AMPARs) […]
Kavli Affiliate: Seth Shipman | Authors: Alejandro Gonzalez-Delgado, Laura Bonillo-Lopez, Milo S Johnson, Nastassia Knoedlseder, Ching-Chung Ko, Yassir Lekbach, Jee-Hwan Oh, Hemaa Selvakumar, Michael C Wold, Zihan Yu, Virginia Aragon, Jeffrey A Gralnick, Marc Guell, Graham Hatfull, Benjamin Keith Keitz, Britt Koskella, Vivek K Mutalik, Jan Peter van Pijkeren and Seth Shipman | Summary: Advanced […]
Kavli Affiliate: Leslie B. Vosshall | Authors: Olivia V. Goldman, Alexandra E. DeFoe, Yanyan Qi, Yaoyu Jiao, Shih-Che Weng, Leah Houri-Zeevi, Priyanka Lakhiani, Takeshi Morita, Jacopo Razzauti, Adriana Rosas-Villegas, Yael N. Tsitohay, Madison M. Walker, Ben R. Hopkins, Mosquito Cell Atlas Consortium, Omar S. Akbari, Laura B. Duvall, Helen White-Cooper, Trevor R. Sorrells, Roshan Sharma, […]
Kavli Affiliate: Mark Ellisman | Authors: Arnulfo B.N. Tunon-Ortiz, Dimitri Trankner, Chandler M. Peterson, Omar Shennib, Fangfei Ye, Jiani Shi, Sarah N. Brockway, Olivia Katherine Raines, Abbey Mahnke, Matthew Grega, Keun-Young Kim, Mark Ellisman, James G. Heys, Moriel Zelikowsky and Megan E Williams | Summary: The homophilic adhesion molecule Kirrel3 drives synapse formation between dentate […]
Kavli Affiliate: Robert E. Clark | Authors: Bert van den Berg, Emily Dunbar, Robert Clark, Arnaud Basle, Shenaz Allyjaun, Hector Newman, Julia Hubbard and Syma Khalid | Summary: Bacteriophages are bacterial viruses that provide alternatives to small-molecule drugs to combat infections by antibiotic-resistant bacteria. To infect a bacterial host, a phage needs to bind to […]
Kavli Affiliate: Edward Chang | Authors: Vardhaan S Ambati, Amit S Persad, Jasleen Kaur, Sanjeev Herr, Emily Cunningham, Abraham Dada, Justyna O Ekert, Quinn Greicius, Alexander Silva, Paul McMillan Villalobos, Niels Olshausen, Youssef Sibih, Sena Oten, Hunter S. Yamada, Gray Umbach, Alexander A Aabedi, Wajd Al-Holou, Jacob Young, Madhumita Sushil, Edward F Chang, Mitchel S. […]
Kavli Affiliate: Su Guo | Authors: Krishnashish Bose, Su Guo and Karnika Bhardwaj | Summary: Paradoxical kinesia—the temporary alleviation of motor deficits by powerful, urgent stimuli in Parkinson’s disease (PD)—remains poorly understood at the neural circuit level. Through chemo-genetic ablation of tyrosine hydroxylase-expressing neurons in larval zebrafish and brain-wide calcium imaging under head-fixed, tail-free conditions, […]