Mosquito sex under lock and key

Kavli Affiliate: Leslie B. Vosshall | Authors: Leah Houri-Zeevi, Madison M. Walker, Jacopo Razzauti, Anurag Sharma, H. Amalia Pasolli and Leslie B. Vosshall | Summary: Female mosquitoes typically mate once in a lifetime, making this singular mating decision critically important for the female. Yet, mosquito mating has been historically viewed as male-guided, with the female […]


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Continuous partitioning of neuronal variability

Kavli Affiliate: Adam S. Charles | Authors: Anuththara Rupasinghe, Adam S Charles and Jonathan W Pillow | Summary: Neural variability poses a major challenge to understanding the information content of neural codes. Recent work by Goris et al. (Nat. Neurosci 2014) has provided new insights into variability in the visual pathway by partitioning it into […]


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Human iPSC derived alveolar macrophages reveal macrophage subtype specific functions of itaconate in M. tuberculosis host defense

Kavli Affiliate: Jean-Laurent Casanova | Authors: Adam Krebs, Tomi Lazarov, Anthony Reynolds, Kimberly Anne Dill-McFarland, Abigail Xie, James Bean, Muxue Du, Olivier Levy, John Buglino, Aaron Zhong, Anna-Lena Neehus, Stephenie Boisson-Dupuis, Jean-Laurent Casanova, Elouise Elizabeth Kroon, Marlo Moller, Thomas R. Hawn, Ting Zhou, Lydia Finley, Marc-Antoine Jean Juste, Dan Fitzgerald, Frederic Geissmann and Michael S […]


Continue.. Human iPSC derived alveolar macrophages reveal macrophage subtype specific functions of itaconate in M. tuberculosis host defense

Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.

Kavli Affiliate: Seth Blackshaw | Authors: Kurt Weir, Pin Lyu, Sangeetha Kandoi, Roujin An, Nicole Pannullo, Isabella Palazzo, Jared Tangeman, Jun Shi, Steven DeVries, Dana Merriman, Jiang Qian and Seth Blackshaw | Summary: Evolutionary adaptation to diurnal vision in ground squirrels has led to the development of a cone-dominant retina, in stark contrast to the […]


Continue.. Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.

Axonal defasciculation is restricted to specific branching points during regeneration of the lateral line nerve in zebrafish

Kavli Affiliate: A. James Hudspeth | Authors: Rohan S Roy and A. J. Hudspeth | Summary: Peripheral nerve regeneration requires precise selection of the appropriate targets of innervation, often in an environment that differs from that during the developmental wiring of the neural circuit. Severed axons of the zebrafish posterior lateral line nerve have the […]


Continue.. Axonal defasciculation is restricted to specific branching points during regeneration of the lateral line nerve in zebrafish

Dopamine release effects on striatal blood oxygenation and whole brain plasticity underlying associative learning

Kavli Affiliate: Darcy Peterka | Authors: Amir Lawen, Isabella K Succi, Daniela Lichtman, Darcy S Peterka, Ishmail J Abdus-Saboor and Itamar Kahn | Summary: Dopaminergic signaling in the nucleus accumbens (NAc) is central to reward-based learning, but its relationship to brain-wide hemodynamics remains unclear. Using concurrent fMRI and dopamine photometry in awake, behaving mice, we […]


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Precision functional mapping reveals less inter-individual variability in the child vs. adult human brain

Kavli Affiliate: Deanna J. Greene | Authors: Damion V Demeter, Matthew Feigelis, Carolina Badke DAndrea, Sana A Ali, Abigail R Baim, Emily Koithan, Jared Stearns, Salma Zreik, Jonathan Ahern, Sujin Park, Sarah E Chang, Ryland L Miller, Jaqueline M Hampton, Bradley L Schlaggar, Scott Marek, Evan M Gordon, Nico UF Dosenbach, Caterina Gratton and Deanna […]


Continue.. Precision functional mapping reveals less inter-individual variability in the child vs. adult human brain

Hippocampal input-driven plasticity of prefrontal interneurons reveals a circuit basis for impaired spatial working memory.

Kavli Affiliate: Vikaas Sohal | Authors: Shana E Silverstein, Thomas T Clarity, Meena S Deshpande, Erik Vaughan, Shoshana Novik, Hector E Yarur, Shiliang Zhang, Valerie S Tsai, Rong Ye, Rachel M Mikofsky, Madeline Hsiang, Avery Bauman, Gabriel Loewinger, Francisco Pereira, Marisela Morales, Vikaas S Sohal, Hugo Tejeda, Joshua A Gordon and David A Kupferschmidt | […]


Continue.. Hippocampal input-driven plasticity of prefrontal interneurons reveals a circuit basis for impaired spatial working memory.

Neural representation of action symbols in primate frontal cortex

Kavli Affiliate: Winrich Freiwald | Authors: Lucas Y Tian, Kedar U Garzón, Adam G Rouse, Mark AG Eldridge, Marc H Schieber, Xiao-Jing Wang, Joshua B Tenenbaum and Winrich A Freiwald | Summary: At the core of intelligence is proficiency in solving new problems, including those that differ dramatically from problems seen before. Problem-solving, in turn, […]


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Goal Uncertainty Attenuates Sensorimotor Adaptation

Kavli Affiliate: Reza Shadmehr | Authors: Sritej Padmanabhan, Reza S Shadmehr, Roberta Klatzky and Jonathan S Tsay | Summary: Implicit sensorimotor adaptation—the automatic correction of movement errors through feedback and practice—is driven by a perceptual prediction error, the mismatch between the perceived movement outcome and its intended goal. While perceptual uncertainty is known to attenuate […]


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