Genomic resources for comparative analyses of obligate avian brood parasitism

Kavli Affiliate: Erich Jarvis | Authors: Rachel A Carroll, Edward Stallknecht Ricemeyer, LaDeana W Hillier, Jeffrey M DaCosta, Ekaterina Osipova, Sara Smith, Gabriel Jamie, Juan Gabriel Martinez, Mercedes Molina-Morales, Tomas Marques-Bonet, Joseph D Manthey, Diana Haddad, Matthew J Fuxjager, Kathleen S Lynch, Jonathan M.D. Wood, Erich Jarvis, Patrick Masterson, Francoise Thibaud-Nissen, Mark Hauber, Claire N […]


Continue.. Genomic resources for comparative analyses of obligate avian brood parasitism

Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS)

Kavli Affiliate: Alexander Szalay | Authors: Tricia R Cottrell, Jeffrey S Roskes, Michael Fotheringham, Emily Cohen, Boyang Zhang, Logan L Engle, Daphne Wang, Elizabeth Will, Joel C Sunshine, Daniel Jimenez-Sanchez, Zhen Zheng, Justina X Caushi, Jiajia Zhang, Nina D’Amiano, Julie Stein-Deutsch, Sonali Uttam, Katie Pirie, Darah Vlaminck, Michelle Mataj, Alexa Fiorante, Nicole Espinosa, Teodora Popa, […]


Continue.. Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS)

Spatial Transcriptomics Reveal Developmental Dynamics of the Human Cerebral Cortex and Striatum

Kavli Affiliate: Li Zhao | Authors: Yunjia Zhang, Youning Lin, Xunan Shen, Xue Xiao, Cai Song, Xiaobo Shi, Tao Zhou, Yanxin Li, Zihan Wu, Zhenkun Zhuang, Chunqiong Li, Meng Li, Feng Wen, Jianlin Liu, Lei Cao, Qiangqiang Zhang, Zhao-Lu Li, Songbo Zhang, Susu Qu, Yaqi Li, Jianhua Yao, Fubaoqian Huang, Xin Liu, Ziqing Deng, Longqi […]


Continue.. Spatial Transcriptomics Reveal Developmental Dynamics of the Human Cerebral Cortex and Striatum

Autism-associated Scn2a haploinsufficiency disrupts in vivo dendritic signaling and impairs flexible decision-making

Kavli Affiliate: Kevin Bender | Authors: Hao Wu, Luqun Shen, Jonathan Indajang, Neil K Savalia, Timothy G Johnson, Jiayin Qu, Kevin J Bender and Alex C Kwan | Summary: SCN2A is a high-confidence risk gene for autism spectrum disorder. Loss-of-function mutations in Scn2a reduce dendritic excitability in neocortical pyramidal cells. However, the impact of Scn2a […]


Continue.. Autism-associated Scn2a haploinsufficiency disrupts in vivo dendritic signaling and impairs flexible decision-making

Reconstructing Waddington’s Landscape from Data

Kavli Affiliate: Eric D. Siggia | Authors: Dillon J. Cislo, M Joaquina Delás, James Briscoe and Eric D. Siggia | Summary: The development of a zygote into a functional organism requires that this single progenitor cell gives rise to numerous distinct cell types. Attempts to exhaustively tabulate the interactions within developmental signaling networks that coordinate […]


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Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

Kavli Affiliate: Denis Wirtz | Authors: Devon E Mason, Megan Goeckel, Sebastian L Vega, Pei-Hsun Wu, Dymonn Johnson, Su-Jin Heo, Denis Wirtz, Jason A Burdick, Levi Wood, Brain Y Chow, Amber N Stratman and Joel D Boerckel | Summary: Vascular morphogenesis requires persistent endothelial cell motility that is responsive to diverse and dynamic mechanical stimuli. […]


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Accessible, realistic genome simulation with selection using stdpopsim

Kavli Affiliate: Scott Small | Authors: Graham Gower, Nathaniel S. Pope, Murillo F. Rodrigues, Silas Tittes, Linh N. Tran, Ornob Alam, Maria Izabel Alves Cavassim, Peter D. Fields, Benjamin C. Haller, Xin Huang, Ben Jeffrey, Kevin Korfmann, Christopher C. Kyriazis, Jiseon Min, Ines Rebollo, Clara T Rehmann, Scott T. Small, Christopher C. R. Smith, Georgia […]


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Circuit inhibition promotes the dynamic reorganization of prefrontal task encoding to support cognitive flexibility

Kavli Affiliate: Vikaas Sohal | Authors: Carlos Johnson-Cruz, Kathleen K.A. Cho and Vikaas S. Sohal | Summary: The mammalian prefrontal cortex encodes variables related to goal-directed behavior, and enables flexibility during environmental changes, making it critical to understand how the dynamic updating vs. stable maintenance of different encodings contribute to behavioral adaptation. We addressed this […]


Continue.. Circuit inhibition promotes the dynamic reorganization of prefrontal task encoding to support cognitive flexibility

Circuit inhibition promotes the dynamic reorganization of prefrontal task encoding to support cognitive flexibility

Kavli Affiliate: Vikaas Sohal | Authors: Carlos Johnson-Cruz, Kathleen K.A. Cho and Vikaas S. Sohal | Summary: The mammalian prefrontal cortex encodes variables related to goal-directed behavior, and enables flexibility during environmental changes, making it critical to understand how the dynamic updating vs. stable maintenance of different encodings contribute to behavioral adaptation. We addressed this […]


Continue.. Circuit inhibition promotes the dynamic reorganization of prefrontal task encoding to support cognitive flexibility

Causal Dynamics of Social Gaze in Primate Prefrontal-Amygdala Networks Revealed by Dynamic Bayesian Modeling

Kavli Affiliate: Anirvan Nandy | Authors: Feng Xing, Siqi Fan, Olga Dal Monte, Monika Jadi, Steve Chang and Anirvan Nandy | Summary: Social gaze is a fundamental channel of primate communication, shaping dynamic interactions and fostering mutual understanding. While prior studies have mapped the behavioral correlates of social gaze across the prefrontal-amygdala circuits, the causal […]


Continue.. Causal Dynamics of Social Gaze in Primate Prefrontal-Amygdala Networks Revealed by Dynamic Bayesian Modeling