A distinctive subset of microglia positioned at the paraventricular zone are dedicated to cleaning the cerebrospinal fluid

Kavli Affiliate: Li Zhao | Authors: Guoyang Zhou, Jian He, Baojie Mao, Guo Cheng, Rui Zhang, Qiang Wang, Xiaoli Liu, Jiaxin Zheng, Ming Wang, Li Zhao, Peng Shi, Xiao Z Shen and Shu Wan | Summary: The interconnected ventricles in the central nervous system are filled with cerebrospinal fluid (CSF) which serves multifaceted roles including […]


Continue.. A distinctive subset of microglia positioned at the paraventricular zone are dedicated to cleaning the cerebrospinal fluid

Single Objective Light Sheet Microscopy allows high-resolution in vivo brain imaging of Drosophila.

Kavli Affiliate: Mark Ellisman | Authors: Francisco Joaquín Tassara, Mariano Barella, Lourdes Simó, Mailen Folgueira, Micaela Rodríguez-Caron, Juan Ignacio Ispizua, Mark H. Ellisman, Horacio O. de la Iglesia, M. Fernanda Ceriani and Julián Gargiulo | Summary: In vivo imaging of dynamic sub-cellular brain structures in Drosophila melanogaster is key to understanding several phenomena in neuroscience. […]


Continue.. Single Objective Light Sheet Microscopy allows high-resolution in vivo brain imaging of Drosophila.

An evolutionarily conserved role for separase in the regulation of nuclear lamins

Kavli Affiliate: Michael Goldberg | Authors: Francesca Cipressa, Gaelle Pennarun, Giuseppe Bosso, Serena Rosignoli, Liliana Tullo, Nadia Schiralli, Chiara Borghi, Alessandro Paiardini, Michael L Goldberg, Pascale Bertrand and Giovanni Cenci | Summary: Separase is a well conserved endopeptidase that facilitates sister chromatid separation at the metaphase-anaphase transition by cleaving cohesins. Beyond its role in chromosome […]


Continue.. An evolutionarily conserved role for separase in the regulation of nuclear lamins

Human precentral gyrus neurons link speech sequences from listening to speaking

Kavli Affiliate: Edward Chang | Authors: Duo Xu, Jason E Chung, Alexander B Silva, Quinn R Greicius, Sean L Metzger, Yizhen Zhang, Matthew K Leonard, Manish K Aghi, Shawn L Hervey-Jumper and Edward F Chang | Summary: Speech perception and production are interconnected processes, but the underlying neural mechanisms remain unclear. We investigated this relationship […]


Continue.. Human precentral gyrus neurons link speech sequences from listening to speaking

Neuromodulation in neural organoids with shell MEAs

Kavli Affiliate: Brian Caffo | Authors: Chris Acha, Derosh George, Lauren C. Diaz, Ziwei Ouyang, Dowlette-Mary M. Alam El Din, Hrishikesh Surlekar, Babak Moghadas, Pratyush Sai R. Rayasam, Yu-Chiao Lai, Lena Smirnova, Brian S. Caffo, Erik C. Johnson and David H. Gracias | Summary: Neural organoids (NOs) have emerged as important tissue engineering models for […]


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No Disconnection Syndrome after Near-Complete Callosotomy

Kavli Affiliate: Michael Miller | Authors: Selin Bekir, Johanna L. Hopf, Theresa Paul, Valerie M. Wiemer, Tyler Santander, Henri E. Skinner, Anna Rada, Friedrich G. Woermann, Thilo Kalbhenn, Barry Giesbrecht, Christian G. Bien, Olaf Sporns, Michael S. Gazzaniga, Lukas J. Volz and Michael B. Miller | Summary: Much of the sensory-motor processing in the human […]


Continue.. No Disconnection Syndrome after Near-Complete Callosotomy

Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs driving type 1 diabetes progression

Kavli Affiliate: Michael Miller | Authors: Rebecca Melton, Sara Jimenez, Weston Elison, Luca Tucciarone, Abigail Howell, Gaowei Wang, Denise Berti, Elisha Beebe, Michael Miller, Chun Zeng, Kennedy Vanderstel, Katha Korgaonkar, Ruth Elgamal, Hannah Mummey, Josh Chiou, Emily Griffin, Irina Kusmartseva, Mark A. Atkinson, Sebastian Preissl, Fabian Theis, Maike Sander and Kyle J Gaulton | Summary: […]


Continue.. Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs driving type 1 diabetes progression

Learning decouples accuracy and reaction time for rapid decisions in a transitive inference task

Kavli Affiliate: Vincent Ferrera | Authors: Fabian A Munoz Silva, Greg Jensen, Maxwell Shinn, Yelda Alkan, John Murray, Herbert Terrace and Vincent P Ferrera | Summary: The accumulation of evidence over time formalized in the drift diffusion model (DDM), has become one of the most prevalent models of deliberative decision-making. To better understand the role […]


Continue.. Learning decouples accuracy and reaction time for rapid decisions in a transitive inference task

A vector-based strategy for olfactory navigation in Drosophila

Kavli Affiliate: Vanessa Ruta | Authors: Andrew F. Siliciano, Sun Minni, Chad Morton, Charles K. Dowell, Noelle B. Eghbali, Juliana Y. Rhee, L. F. Abbott and Vanessa Ruta | Summary: Odors serve as essential cues for navigation. Although tracking an odor plume has been modeled as a reflexive process, it remains unclear whether animals can […]


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Full inter-hemispheric integration sustained by a fraction of posterior callosal fibers

Kavli Affiliate: Michael Miller | Authors: Tyler Santander, Selin Bekir, Theresa Paul, Jessica M Simonson, Valerie M Wiemer, Henri Etel Skinner, Johanna L Hopf, Anna Rada, Friedrich G Woermann, Thilo Kalbhenn, Barry Giesbrecht, Christian G Bien, Olaf Sporns, Michael S Gazzaniga, Lukas J Volz and Michael B Miller | Summary: The dynamic integration of the […]


Continue.. Full inter-hemispheric integration sustained by a fraction of posterior callosal fibers