dbos – Kavli Institute Pre-Print Publications

A polymeric, PDMS-based large-scale skull replacement suitable for optical and mechanical access for long-term neuronal imaging, electrophysiology, and optogenetics

Posted by dbos April 20, 2025April 21, 2025Columbia, This Week: Neuroscience

Kavli Affiliate: Rafael Yuste | Authors: Kengo Takahashi, Gerhardus Jan Huis in ‘t Veld, Davide Benedetti, Jun-Ying Wang, Samuel Pontes Quero, Rafael Yuste, Cyriel M.A. Pennartz and Umberto Olcese | Summary: Many techniques to record and manipulate neuronal activity across large portions of the vertebrate brain, such as widefield and two-photon calcium imaging, electrophysiology, and […]

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Fast and accessible morphology-free functional fluorescence imaging analysis

Posted by dbos April 20, 2025April 21, 2025Hopkins, This Week: Neuroscience

Kavli Affiliate: Kishore V. Kuchibhotla and Adam S. Charles | Authors: Alejandro A Estrada Berlanga, Gabrielle Kang, Amanda Kwok, Thomas Broggini, Jennifer Lawlor, Kishore Kuchibhotla, David Kleninfeld, Gal Mishne and Adam Charles | Summary: Optical calcium imaging is a powerful tool for recording neural activity across a wide range of spatial scales, from dendrites and […]

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Survey of hippocampal responses to sound in naive mice reveals widespread activation by broadband noise onsets

Posted by dbos April 20, 2025April 21, 2025This Week: Neuroscience, UCSF

Kavli Affiliate: Andrea Hasenstaub | Authors: James Bigelow, Toshiaki Suzuki, Yulang Wu, Ying Hu and Andrea R Hasenstaub | Summary: Recent studies suggest some hippocampal (HC) neurons respond to passively presented sounds in naive subjects, but the specificity and prevalence of these responses remain unclear. We used Neuropixels probes to record unit activity in HC […]

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D3 dopamine receptors implicate a subtype of medium spiny neuron in the aversive effects of antipsychotic medications

Posted by dbos April 20, 2025April 21, 2025This Week: Neuroscience, UCSF

Kavli Affiliate: Kevin Bender | Authors: Elinor Lewis, Jessie Muir, Ling C Li, Julianna Glienke, Sarah Warren Gooding, Kevin Bender, Christina Kim and Jennifer Whistler | Summary: Second generation antipsychotics (SGAs) are widely used clinical tools, yet they often cause negative side effects and take weeks to become effective, leading to poor patient compliance. The […]

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Mosquito sex under lock and key

Posted by dbos April 19, 2025April 21, 2025Rockefeller, This Week: Neuroscience

Kavli Affiliate: Leslie B. Vosshall | Authors: Leah Houri-Zeevi, Madison M. Walker, Jacopo Razzauti, Anurag Sharma, H. Amalia Pasolli and Leslie B. Vosshall | Summary: Female mosquitoes typically mate once in a lifetime, making this singular mating decision critically important for the female. Yet, mosquito mating has been historically viewed as male-guided, with the female […]

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Accurate Point Defect Energy Levels from Non-Empirical Screened Range-Separated Hybrid Functionals: the Case of Native Vacancies in ZnO

Posted by dbos April 18, 2025April 21, 2025Berkeley, This Week: Nanoscience

Kavli Affiliate: Jeffrey B. Neaton | First 5 Authors: Sijia Ke, Stephen E. Gant, Leeor Kronik, Jeffrey B. Neaton, | Summary: We use density functional theory (DFT) with non-empirically tuned screened range-separated hybrid (SRSH) functionals to calculate the electronic properties of native zinc and oxygen vacancy point defects in ZnO, and we predict their defect […]

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Detecting Intermediate-mass Black Holes Using Quasar Microlensing

Posted by dbos April 18, 2025April 21, 2025Peking, This Week: Astrophysics

Kavli Affiliate: Luis C. Ho | First 5 Authors: Zihao Wu, Luis C. Ho, , , | Summary: Recent studies suggest that numerous intermediate-mass black holes (IMBHs) may wander undetected across the Universe, emitting little radiation. These IMBHs largely preserve their birth masses, offering critical insights into the formation of heavy black hole seeds and […]

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Q-balls Under Spontaneously Broken U(1) Symmetry

Posted by dbos April 18, 2025April 21, 2025This Week: Astrophysics, Tokyo

Kavli Affiliate: Masahiro Kawasaki | First 5 Authors: Masahiro Kawasaki, Kai Murai, Fuminobu Takahashi, , | Summary: We study the evolution of Q-balls under a spontaneously broken global $U(1)$ symmetry. Q-balls are stabilized by the conservation of $U(1)$ charge, but when the symmetry is spontaneously broken, the resulting Nambu-Goldstone (NG) boson can carry charge away […]

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ATG2A engages Rab1a and ARFGAP1 positive membranes during autophagosome biogenesis

Posted by dbos April 17, 2025April 21, 2025This Week: Neuroscience, Yale

Kavli Affiliate: Pietro De Camilli | Authors: Devin M Fuller, Yumei Wu, Florian Schueder, Burha Rasool, Shanta Nag, Justin L. Korfhage, Rolando Garcia-Milian, Katerina D Melnyk, Joerg Bewersdorf, Pietro De Camilli and Thomas Melia | Summary: Autophagosomes form from seed membranes that expand through bulk-lipid transport via the bridge-like lipid transporter ATG2. The origins of […]

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Seasonal brain regeneration and chromosome instability are linked to selection on DNA repair in Sorex araneus

Posted by dbos April 17, 2025April 21, 2025Rockefeller, This Week: Neuroscience

Kavli Affiliate: Erich Jarvis | Authors: William R Thomas, Tanya M Lama, Diana Moreno-Santillan, Marta Farre, Cecilia Baldoni, Linelle Abueg, Jennifer Balacco, Olivier Fedrigo, Giulio Formenti, Nivesh Jain, Jacquelyn Mountcastle, Tatiana Tilley, Alan Tracey, David A Ray, Dina K. N. Dechmann, Dominik von Elverfeldt, John Nieland, Angelique P Corthals, Erich Jarvis and Liliana M Davalos […]

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