Macroscopic Analyses of RNA-Seq Data to Reveal Chromatin Modifications in Aging and Disease

Kavli Affiliate: Hana El-Samad | Authors: Achal Mahajan, Francesca Ratti, Ban Wang, Hana El-Samad, James H. Kaufman and Vishrawas Gopalakrishnan | Summary: Regulation of gene expression is fundamental for proper cellular function, and is constrained by the local chromatin environment of each gene, which varies spatially along the chromosome and is shaped by epigenetic modifications. […]


Continue.. Macroscopic Analyses of RNA-Seq Data to Reveal Chromatin Modifications in Aging and Disease

A neutralizing human antibody induces movement of the HCoV-229E receptor binding domain

Kavli Affiliate: Robert Edwards | Authors: Mera F. Liccione, Trevor Scobey, Heather M. Froggatt, Camryn Pajon, Boyd L. Yount, Qi Yin, Taylor N. Spence, Emmanuel B. Walter, Kevin O. Saunders, Robert J. Edwards, Ralph S. Baric, Barton F. Haynes, Derek W. Cain, Timothy P. Sheahan and Daniel Wrapp | Summary: HCoV-229E is an endemic Alphacoronavirus […]


Continue.. A neutralizing human antibody induces movement of the HCoV-229E receptor binding domain

Early development of direction selectivity in higher visual cortex

Kavli Affiliate: Kristina Nielsen | Authors: Dallas C Khamiss, Augusto A Lempel, Brandon R Nanfito and Kristina Juliane Nielsen | Summary: A fundamental aspect of visual motion processing is the computation of motion direction. In ferrets, as in primates, selectivity for motion direction is found both in early cortical stages like the primary visual cortex […]


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Condenzymes: Biomolecular condensates with inherent catalytic activities

Kavli Affiliate: Wei Min | Authors: Michael W Chen, Xiao Guo, Mina Farag, Naixin Qian, Xiaowei Song, Anton Ni, Vicky Liu, Xia Yu, Yuefeng Ma, Leshan Yang, Wen Yu, Matthew King, Joonho Lee, Richard N Zare, Wei Min, Rohit V Pappu and Yifan Dai | Summary: We report the discovery that chemical reactions can be […]


Continue.. Condenzymes: Biomolecular condensates with inherent catalytic activities

Oxytocin receptor absence reduces selectivity in peer relationships and alters neurochemical release dynamics in prairie voles

Kavli Affiliate: Devanand Manoli | Authors: Alexis M Black, Natsumi Komatsu, Jiaxuan Zhao, Scarlet R Taskey, Nicole S Serrano, Ruchira Sharma, Devanand S. Manoli, Markita P Landry and Annaliese Beery | Summary: Friendships, or selective peer relationships, are a vital component of healthy social functioning in humans, while deficits in these relationships are associated with […]


Continue.. Oxytocin receptor absence reduces selectivity in peer relationships and alters neurochemical release dynamics in prairie voles

Complementary Probes of Gravitational Radiation States

Kavli Affiliate: Frank Wilczek | First 5 Authors: Sreenath K. Manikandan, Frank Wilczek, , , | Summary: We demonstrate that the statistical fluctuations in resonant radiation detectors operating in homodyne and heterodyne modes offers additional, complementary information to that obtained from their direct operation as click detectors. We use this to refine tests of the […]


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Probing Quantum Structure in Gravitational Radiation

Kavli Affiliate: Frank Wilczek | First 5 Authors: Sreenath K. Manikandan, Frank Wilczek, , , | Summary: Gravitational radiation from known astrophysical sources is conventionally treated classically. This treatment corresponds, implicitly, to the hypothesis that a particular class of quantum-mechanical states — the so-called coherent states — adequately describe the gravitational radiation field. We propose […]


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Truly Confining Supersymmetric Gauge Theories

Kavli Affiliate: Hitoshi Murayama | First 5 Authors: Riku Ishikawa, Hitoshi Murayama, Shota Saito, , | Summary: We classify “truly confining” (t-confining) supersymmetric gauge theories, in which no center charges can be screened, and Wilson loops in the fundamental representation are therefore expected to exhibit an area law. In all cases, we identify the condensation […]


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A Cosmic Miracle: A Remarkably Luminous Galaxy at $z_{rm{spec}}=14.44$ Confirmed with JWST

Kavli Affiliate: Robert A. Simcoe | First 5 Authors: Rohan P. Naidu, Pascal A. Oesch, Gabriel Brammer, Andrea Weibel, Yijia Li | Summary: JWST has revealed a stunning population of bright galaxies at surprisingly early epochs, $z>10$, where few such sources were expected. Here we present the most distant example of this class yet — […]


Continue.. A Cosmic Miracle: A Remarkably Luminous Galaxy at $z_{rm{spec}}=14.44$ Confirmed with JWST

Prototype sub-wavelength structure anti-reflection coating on alumina filters for ground-based CMB telescopes

Kavli Affiliate: Tomotake Matsumura | First 5 Authors: Kosuke Aizawa, Ryosuke Akizawa, Scott Cray, Shaul Hanany, Shotaro Kawano | Summary: We present designs and fabrication of sub-wavelength anti-reflection (AR) structures on alumina for infrared absorptive filters with passbands near 30, 125, and 250 GHz. These bands are widely used by ground-based instruments measuring the cosmic […]


Continue.. Prototype sub-wavelength structure anti-reflection coating on alumina filters for ground-based CMB telescopes