From observing strategies to velocity dispersion bias: forward modeling unresolved binaries in ultra-faint dwarf galaxies

Kavli Affiliate: Lina Necib | Summary:Ultra-faint dwarf galaxies (UFDs) in the Milky Way are ideal probes of low-mass galaxy formation and dark matter because they are highly dark-matter dominated. In the lowest-mass systems, however, unresolved binary orbital motion complicates dynamical mass estimates by inflating measured velocity dispersions and biasing the interpretation of the inferred masses. […]


Continue.. From observing strategies to velocity dispersion bias: forward modeling unresolved binaries in ultra-faint dwarf galaxies

Observing and evading quantum back-action on a kilogram-scale oscillator

Kavli Affiliate: Nergis Mavalvala | Summary:Continuous quantum displacement measurements are fundamentally limited by a trade-off between readout imprecision and measurement back-action, constrained by the Heisenberg uncertainty principle. In the Laser Interferometric Gravitational-Wave Observatory (LIGO), these two quantum noise components dominate much of the observation band, making it an excellent testbed. We induce a sub-Hz-linewidth optomechanical […]


Continue.. Observing and evading quantum back-action on a kilogram-scale oscillator

RNA trans-splicing treatment for Duchenne muscular dystrophy

Kavli Affiliate: Samuel Pfaff | Authors: Ryan H. Hsu, Claire E. Williams, Geraldine Maier, Miriam Gullo, Karen Lettieri, Cindy J. Alvarez, Kip J. Hermann, Stella Kramer, Satchidananda Panda, Lukas C. Bachmann and Samuel L. Pfaff | Summary: Duchenne muscular dystrophy (DMD) is a fatal disorder caused by dystrophin mutations, leading to progressive muscle degeneration and cardiac failure. […]


Continue.. RNA trans-splicing treatment for Duchenne muscular dystrophy

Reconstructing the Projected Dark Matter Field across 0.1-100 Mpc Scales from the SDSS Survey

Kavli Affiliate: Roberto Maiolino | Summary:Dark matter sets the gravitational environment in which galaxies form and evolve, but cannot be observed directly. We present a conditional diffusion model that reconstructs the projected dark matter density field from the galaxy stellar-mass density field for direct application to galaxy surveys. The model is trained on CAMELS and […]


Continue.. Reconstructing the Projected Dark Matter Field across 0.1-100 Mpc Scales from the SDSS Survey

On the Clustering Bias of Unresolved Gamma-Ray Sources

Kavli Affiliate: Aaron Roodman | Summary:The Unresolved $γ$-Ray Background (UGRB) encodes the collective emission of source populations that are too faint to be detected individually, and its cross-correlation with tracers of the large-scale structure has emerged as a powerful tool to characterize those populations. In this work, we analyze the weak-lensing–UGRB cross-correlation using a reference […]


Continue.. On the Clustering Bias of Unresolved Gamma-Ray Sources

Rubin LSST DP2 unveils almost-dark galaxies in the Virgo Cluster

Kavli Affiliate: Kevin Reil | Summary:Galaxies with the faintest surface brightness are currently known only in the Local Group. Similar objects should exist beyond our vicinity and are crucial for understanding galaxy evolution, structure, and dark matter content, yet surveys have not reached the depth required to detect them systematically. We present a population of […]


Continue.. Rubin LSST DP2 unveils almost-dark galaxies in the Virgo Cluster

Hippocampo-septal inhibitory feedback controls the medial septal circuit as a function of brain state, pyramidal cell activity and movement speed.

Kavli Affiliate: Attila Losonczy | Authors: Andor Domonkos, Daniel Schlingloff, Balint Kiraly, Litsa Ledri, Marta Jelitai, Gergely Turi, Rita M Karlocai, Edit Papp, Panna Hegedus, Gabor Nyiri, Attila I Gulyas, Tamas F Freund, Karl Deisseroth, Attila Losonczy, Balazs Hangya and Viktor Varga | Summary: Encoding novel experiences and retrieving stored information rely on the hippocampal […]


Continue.. Hippocampo-septal inhibitory feedback controls the medial septal circuit as a function of brain state, pyramidal cell activity and movement speed.

A Binary Flux Calibrator Reveals the Scientific Potential of Short-integration JWST MIRI Imaging to Directly Detect sub-Jupiter Exoplanets

Kavli Affiliate: Andrew Vanderburg | Summary:We report the direct imaging detection of a stellar companion to HD 101452 (HIP 56925; Gaia DR3 5384905720847544192), an A star historically used as an infrared flux calibrator. The companion was identified from an asymmetry in the stellar PSF using short-integration (<1 min), noncoronagraphic JWST MIRI imaging from 15 – […]


Continue.. A Binary Flux Calibrator Reveals the Scientific Potential of Short-integration JWST MIRI Imaging to Directly Detect sub-Jupiter Exoplanets

Massive Galaxy Halos Contain Less Inner Dark Matter Than Predicted

Kavli Affiliate: Roberto Maiolino | Summary:The mass profiles of galaxy halos encode how baryons reshape dark matter distribution, yet direct observational constraints across the full radial range remain scarce. Here we combine stellar kinematics from MaNGA, H I dynamical measurements from ALFALFA, and independently calibrated halo masses of SDSS groups to statistically reconstruct the mass […]


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Single-molecule imaging of DNA repair and cytoplasmic rigidification in intracellular bacteria

Kavli Affiliate: Lindsay Baker | Authors: Fiona Anne Sargison, Nicolas Cherif Ducrot, Clara Kummerer, Claire Qu, Treasa B O’Hagan, Elliott Haywood, Anju Kudhail, Amy N Moores, Lindsay Baker and Stephan Uphoff | Summary: DNA damage is an important component of the antibacterial response of phagocytes, but which DNA repair mechanisms are active in intracellular bacteria […]


Continue.. Single-molecule imaging of DNA repair and cytoplasmic rigidification in intracellular bacteria