Disease-associated variants alter a novel physiological role of hnRNP H2 in neuronal development

Kavli Affiliate: Rui Costa | Authors: Afonso Lourinho, Marta S. Silva, Emanuel Tahiri, Marco D’Ambrosio, Ana D. Pinto, Saray Calvo Parra, Giovana De Pietro, Guilherme Galvao, Ana B. Caniceiro, Luis Pereira de Almeida, Paulo Pinheiro, Irina S. Moreira, Rui Jorge Nobre, Miranda Mele, Andrzej W. Cwetsch, Carlos B. Duarte and Rui O Costa | Summary: […]


Continue.. Disease-associated variants alter a novel physiological role of hnRNP H2 in neuronal development

WTR: A Toolkit for Functional Anterograde Transneuronal Circuit Mapping

Kavli Affiliate: Xin Duan and Lily Jan | Authors: Chao Chen, Ruogu Liu, Aijia Yi-Luo, Xiaoyan Cao, Jitao Hu, Shikang Guan, Si-yuan Chang, Xiaoli Cui, Wei Zhou, Fei Zhao, Chun-Teng Huang, Xin Duan, Lily Y. Jan and Tongfei A. Wang | Summary: The brain coordinates animal physiology and behavior via neuronal circuits. To understand and […]


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Local polarization control of optical tweezer arrays

Kavli Affiliate: Nelson Darkwah Oppong| Summary:Optical tweezer arrays trapping ultracold atoms and molecules are a versatile quantum science platform with broad impact in quantum simulation, quantum computation, and quantum metrology. The polarization dependence of anisotropic vector and tensor light shifts offers a degree of freedom for precise quantum state engineering of trapped particles. Similarly, state-selective […]


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TestPrism: Rethinking Test Evaluation Beyond a Single Reference

Kavli Affiliate: Wei Gao| Summary:Large language model (LLM) coding agents have advanced test generation across diverse programming tasks. However, the common practice of evaluating tests against a single reference solution overlooks alternative valid implementations and can overstate test quality. We introduce TestPrism, comprising 300 test tasks from 17 sources and 3000 candidate implementations, evenly split […]


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Dynamical many-body control of high harmonic generation in a Mott insulator

Kavli Affiliate: David Hsieh| Summary:High harmonic generation (HHG) has emerged as a powerful probe of ultrafast electron dynamics in solids. However, in strongly correlated materials, where electronic excitations arise from many-body interactions rather than single-particle band dispersion, the field remains in its infancy. Here, we report HHG up to the 23$^rd$ order in the prototypical […]


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Testing Extra-Dimensional Gravitational-Wave Polarizations with Compact-Binary Observations

Kavli Affiliate: Lijing Shao | Summary:Extra spatial dimensions arise naturally in theories beyond four-dimensional general relativity (GR), but direct observational evidence remains elusive. Gravitational waves offer a distinctive probe: geometric projection onto the observable three-dimensional spatial subspace can produce apparent tensor, vector, and scalar polarizations. We consider one additional spatial dimension and a two-mode tensor-wave […]


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Sub-MHz SWAP spectroscopy of two-level systems in superconducting qubits

Kavli Affiliate: Oskar Painter | Summary:An outstanding challenge in superconducting quantum circuits is mitigating loss from two-level system (TLS) defects. SWAP spectroscopy with flux-tunable qubits can detect individual TLSs, but the Rabi chevrons that signal coherent exchange have been observed only for the most strongly coupled defects. Here, we introduce a sequence with fast flux […]


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Pushing Variability Searches to Extreme Dwarf Galaxies with the Vera C. Rubin Observatory Data Preview 2

Kavli Affiliate: Claudio Ricci | Summary:Galaxies with stellar masses $M_star<10^8~M_odot$, hereafter referred to as extreme dwarf galaxies (EDGs), represent one of the least explored regimes in the search for accreting intermediate-mass black holes. Using the recent Vera C. Rubin Observatory Data Preview 2 (DP2; covering 2025-04-25 to 2026-01-06), we present the first systematic search for […]


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Reciprocal control of the stomach and intestine by viscerosensory neurons in caudal brainstem

Kavli Affiliate: Zachary Knight and Kevin Yackle | Authors: Naz Dundar, Ilayda Alkislar, Brooke C Jarvie, Ho Namkung, Kathryn Xie, Mahekdeep Kaur, Queenie Li, Anagh S Ravi, Alejandro Lopez, Antionette Spina, Longhui Qui, Truong Ly, Jun Oh, Kevin Yackle and Zachary A Knight | Summary: Digestion requires precisely timed transit of food through the gastrointestinal […]


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Genetic accessibility, not superior fitness, determines which anti-HBs antibody escape variants are selected in patients

Kavli Affiliate: Charles M. Rice | Authors: Yingpu Yu, Eleftherios Michailidis, Leon Louis Seifert, Mengyin Zhang, Chenhui Zou, Catherine Freije, Georgios Dangas, Antonis Athanasiadis, Andreas Puschnik, Audrey Hanson, Evelyn Rocha, Yi-Pei Chen, Xupeng Hong, Corrine Quirk, Yichen Zhou, Michael A Schmid, Florian A Lempp, Charles M Rice, William Schneider and Ype P De Jong | […]


Continue.. Genetic accessibility, not superior fitness, determines which anti-HBs antibody escape variants are selected in patients