Kavli Affiliate: Keri Martinowich | Authors: Lionel A Rodriguez, Matt N Tran, Renee Garcia-Flores, Elizabeth A Pattie, Sun-Hong Kim, Joo Heon Shin, Yong Kyu Lee, Heena R Divecha, Carly Montoya, Andrew E Jaffe, Leonardo Collado Torres, Stephanie Cerceo Page and Keri Martinowich | Summary: The lateral septum (LS), a GABAergic structure located in the basal […]
Kavli Affiliate: Erich Jarvis | Authors: Delphine Lariviere, Linelle Abueg, Nadolina Brajuka, Cristobal Gallardo-Alba, Bjorn Gruning, Byung June Ko, Alex Ostrovsky, Marc Palmada-Flores, Brandon D. Pickett, Keon Rabbani, Jennifer R. Balacco, Mark Chaisson, Haoyu Cheng, Joanna Collins, Alexandra Denisova, Olivier Fedrigo, Guido Roberto Gallo, Alice Maria Giani, Grenville MacDonald Gooder, Nivesh Jain, Cassidy Johnson, Heebal […]
Kavli Affiliate: Patricia Janak | Authors: Kurt M. Fraser, Tabitha H. Kim, Matilde Castro, Céline Drieu, Yasmin Padovan-Hernandez, Bridget Chen, Fiona Pat, David J. Ottenheimer and Patricia H. Janak | Summary: The ability to evaluate and select a preferred option among a variety of available offers is an essential aspect of goal-directed behavior. Dysregulation of […]
Kavli Affiliate: John Rubenstein | Authors: Rinaldo Catta-Preta, Susan Lindtner, Athena Ypsilanti, James Price, Armen Abnousi, Linda Su-Feher, Yurong Wang, Ivan Juric, Ian Jones, Jennifer Akiyama, Ming Hu, Yin Shen, Axel Visel, Len Pennacchio, Diane Dickel, John Rubenstein and Alex Nord | Summary: Transcription factors (TFs) bind combinatorially to genomic cis-regulatory elements (cREs), orchestrating transcription […]
Kavli Affiliate: Li Zhao | Authors: Samuel Khodursky, Eric B Zheng, Nicolas Svetec, Sylvia M Durkin, Sigi Benjamin, Alice Gadau, Xia Wu and Li Zhao | Summary: The evolution of regulatory regions in the genome plays a critical role in shaping the diversity of life. While this process is primarily sequence-dependent, the enormous complexity of […]
Kavli Affiliate: Menno Witter | Authors: Katrine Sjaastad Hanssen, Nicolai Winter-Hjelm, Salome Nora Niethammer, Asgeir Kobro-Flatmoen, Menno P. Witter, Axel Sandvig and Ioanna Sandvig | Summary: Engineered biological neural networks are indispensable tools for investigating neural function in both healthy and diseased states from the subcellular to the network level. Neurons in vitro self-organize over […]
Kavli Affiliate: Li Zhao | Authors: Junhui Peng and Li Zhao | Summary: Although previously thought to be unlikely, recent studies have shown that de novo gene origination from previously non-genic sequences is a common mechanism for gene innovation in many species and taxa. These young genes provide a unique set of candidates to study […]
Kavli Affiliate: Timothy Brown | Authors: Kristian Davidsen, Jonathan S Marvin, Abhi Aggarwal, Timothy A Brown and Lucas B Sullivan | Summary: Intracellular levels of the amino acid aspartate are responsive to changes in metabolism in mammalian cells and can correspondingly alter cell function, highlighting the need for robust tools to measure aspartate abundance. However, […]
Kavli Affiliate: Michael Stryker | Authors: Luciano Dyballa, Andra M Rudzite, Mahmood S Hoseini, Mishek Thapa, Michael P Stryker, Greg D Field and Steven W Zucker | Summary: The retina and primary visual cortex (V1) both exhibit diverse neural populations sensitive to diverse visual features. Yet it remains unclear how neural populations in each area […]
Kavli Affiliate: Eric D. Siggia | Authors: Teresa Krammer, Hannah Taylor Stuart, Elena Gromberg, Keisuke Ishihara, Manuela Melchionda, Jingkui Wang, Elena Costantini, Stefanie Lehr, Dillon Cislo, Laura Arbanas, Alexandra Hoermann, Ralph Alexander Neumueller, Nicola Elvassore, Eric Siggia, James Briscoe, Anna Kicheva and Elly Margaret Tanaka | Summary: Organoids can undergo pattern formation by spontaneously forming […]