Uncovering population contributions to the extracellular potential in the mouse visual system using Laminar Population Analysis

Kavli Affiliate: Anders Dale | Authors: Atle Eskeland Rimehaug, Anders M. Dale, Anton Arkhipov and Gaute T. Einevoll | Summary: The local field potential (LFP), the low-frequency part of the extracellular potential, reflects transmembrane currents in the vicinity of the recording electrode. Thought mainly to stem from currents caused by synaptic input, it provides information […]


Continue.. Uncovering population contributions to the extracellular potential in the mouse visual system using Laminar Population Analysis

Molecular and cellular dynamics of the developing human neocortex at single-cell resolution

Kavli Affiliate: Xin Duan, Arnold R. Kriegstein, and Xin Duan | Authors: Li Wang, Cheng Wang, Juan A. Moriano, Songcang Chen, Shaobo Zhang, Tanzila Mukhtar, Shaohui Wang, Arantxa Cebrian-Silla, Qiuli Bi, Jonathan J. Augustin, Lilian G. de Oliveira, Mengyi Song, Xinxin Ge, Guolong Zuo, Mercedes F. Paredes, Eric J. Huang, Arturo Alvarez-Buylla, Xin Duan, Jingjing […]


Continue.. Molecular and cellular dynamics of the developing human neocortex at single-cell resolution

Simultaneous, cortex-wide and cellular-resolution neuronal population dynamics reveal an unbounded scaling of dimensionality with neuron number

Kavli Affiliate: Alipasha Vaziri | Authors: Jason Manley, Jefferey Demas, Hyewon Kim, Francisca Martinez Traub and Alipasha Vaziri | Summary: The brain’s remarkable properties arise from collective activity of millions of neurons. Widespread application of dimensionality reduction to multi-neuron recordings implies that neural dynamics can be approximated by low-dimensional “latent” signals reflecting neural computations. However, […]


Continue.. Simultaneous, cortex-wide and cellular-resolution neuronal population dynamics reveal an unbounded scaling of dimensionality with neuron number

Value construction through sequential sampling explains serial dependencies in decision making

Kavli Affiliate: Daphna Shohamy and Michael Shadlen | Authors: Ariel Zylberberg, Akram Bakkour, Daphna Shohamy and Michael N Shadlen | Summary: Many decisions are expressed as a preference for one item over another. When these items are familiar, it is often assumed that the decision maker assigns a value to each of the items and […]


Continue.. Value construction through sequential sampling explains serial dependencies in decision making

Long-Term Potentiation Produces a Sustained Expansion of Synaptic Information Storage Capacity in Adult Rat Hippocampus

Kavli Affiliate: Terrence Sejnowski | Authors: Dana E Cobb-Lewis, Anne George, Shannon Hu, Katherine Packard, Mingyuan Song, Oliver Nguyen-Lopez, Emily Ikematsu Tesone, Jhanay Rowden, Julie Wang and Maya Opendak | Summary: Long-term potentiation (LTP) has become a standard model for investigating synaptic mechanisms of learning and memory. Increasingly, it is of interest to understand how […]


Continue.. Long-Term Potentiation Produces a Sustained Expansion of Synaptic Information Storage Capacity in Adult Rat Hippocampus

The lateral habenula integrates age and experience to promote social transitions in developing rats

Kavli Affiliate: Maya Opendak | Authors: Dana E Cobb-Lewis, Anne George, Shannon Hu, Katherine Packard, Mingyuan Song, Oliver Nguyen-Lopez, Emily Ikematsu Tesone, Jhanay Rowden, Julie Wang and Maya Opendak | Summary: Social behavior deficits are an early-emerging marker of psychopathology and are linked with early caregiving quality. However, the infant neural substrates linking early care […]


Continue.. The lateral habenula integrates age and experience to promote social transitions in developing rats

Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition

Kavli Affiliate: Elizabeth Hillman, Mark Ellisman and Darcy Peterka | Authors: Alexander R. Goldberg, Athanassios Dovas, Daniela Torres, Sohani Das Sharma, Angeliki Mela, Edward M. Merricks, Markel Olabarria, Leila Abrishami Shokoohm, Hanzhi T. Zhao, Corina Kotidis, Peter Calvaresi, Ashwin Viswanathan, Matei A. Banu, Aida Razavilar, Tejaswi D. Sudhakar, Ankita Saxena, Cole Chokran, Nelson Humala, Aayushi […]


Continue.. Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition

RAPSYN-Mediated Neddylation of BCR-ABL Alternatively Determines the Fate of Philadelphia Chromosome-positive Leukemia

Kavli Affiliate: Li Zhao | Authors: mengya Zhao, Beiying Dai, Xiaodong Li, Yixin Zhang, Chun Qiao, Yaru Qin, Zhao Li, Qingmei Li, Shuzhen Wang, Yong Yang and Yijun Chen | Summary: Philadelphia chromosome-positive (Ph+) leukemia is a fatal hematological malignancy. Although standard treatments with tyrosine kinase inhibitors (TKI) have achieved remarkable success in prolonging patient […]


Continue.. RAPSYN-Mediated Neddylation of BCR-ABL Alternatively Determines the Fate of Philadelphia Chromosome-positive Leukemia

Simultaneous multi-transient linear-combination modeling of MRS data improves uncertainty estimation

Kavli Affiliate: Jeremias Sulam | Authors: Helge J Zollner, Christopher B. Davies-Jenkins, Dunja B. Simicic, Assaf Tal, Jeremias Sulam and Georg Oeltzschner | Summary: TPurpose The interest in applying and modeling dynamic MRS has recently grown. 2D modeling yields advantages for the precision of metabolite estimation in interrelated MRS data. However, it is unknown whether […]


Continue.. Simultaneous multi-transient linear-combination modeling of MRS data improves uncertainty estimation