Spatially-resolved molecular sex differences at single cell resolution in the adult human ventromedial and arcuate hypothalamus

Posted by dbos Hopkins

Kavli Affiliate: Keri Martinowich | Authors: Bernard Mulvey, Yi Wang, Heena R Divecha, Svitlana V Bach, Kelsey D Montgomery, Sophia Cinquemani, Atharv Chandra, Yufeng Du, Ryan A Miller, Joel E Kleinman, Stephanie Cerceo Page, Thomas M Hyde, Keri Martinowich, Stephanie C Hicks, Kasper D Hansen and Kristen R Maynard | Summary: The hypothalamus contains multiple […]


Continue.. Spatially-resolved molecular sex differences at single cell resolution in the adult human ventromedial and arcuate hypothalamus

Identification of a Thermogenic Target in the Dorsal Raphe Nucleus for Weight Management

Posted by dbos Rockefeller

Kavli Affiliate: Jeffrey M. Friedman and Nathaniel Heintz | Authors: Alexandre Moura-Assis, Kaja Plucinska, Aiste Baleisyte, David David, Kyle Pellegrino, Luca Parolari, Parolari T Shaked, Keith J Page, Douglas W Douglas, Thomas S Carrol, Jose G Grajales-Reyes, Daxiang Na, Hans H Schiffer, Yun Chen, Huikai Sun, Nidhi Cohen, Holger Monenschein, Daniel F Barker, Maria J […]


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Towards individualized deep brain stimulation: A stereoencephalography-based workflow for unbiased neurostimulation target identification

Posted by dbos UCSF

Kavli Affiliate: Edward Chang | Authors: Jeremy Saal, Kelly Kadlec, Anusha B. Allawala, Lucille Johnston, Ryan Leriche, Ritwik Vatsyayan, Yiyuan Han, Audrey Kist, Tommaso Di Ianni, Heather E. Dawes, Edward F. Chang, A Moses Lee, Andrew D. Krystal, Khaled Moussawi, Prasad Shirvalkar and Kristin K. Sellers | Summary: Background: Deep-brain stimulation (DBS) is increasingly being […]


Continue.. Towards individualized deep brain stimulation: A stereoencephalography-based workflow for unbiased neurostimulation target identification

Separable Dorsal Raphe Dopamine Projections Mimic the Facets of a Loneliness-like State

Posted by dbos UCSD / Salk

Kavli Affiliate: Kay Tye | Authors: Christopher R Lee, Gillian A Matthews, Mackenzie E Lemieux, Elizabeth M Wasserlein, Matilde Borio, Raymundo L Miranda, Laurel R Keyes, Gates P Schneider, Caroline Jia, Andrea Tran, Faith Aloboudi, May G Chan, Enzo Peroni, Grace Pereira, Alba López-Moraga, Anna Pallé, Eyal Y Kimchi, Nancy Padilla-Coreano, Romy Wichmann and Kay […]


Continue.. Separable Dorsal Raphe Dopamine Projections Mimic the Facets of a Loneliness-like State

Hebb’s Vision: The Structural Underpinnings of Hebbian Assemblies

Posted by dbos UCSF

Kavli Affiliate: Reza Abbasi Asl | Authors: Julian A Wagner-Carena, Sai Kate, Trevor Riordan, Reza Abbasi-Asl, Joe Aman, Adam Amster, Agnes L Bodor, Derrick Brittain, JoAnn Buchanan, Michael A Buice, Daniel J Bumbarger, Forrest Collman, Nuno Macarico da Costa, Daniel J Denman, Saskia EJ de Vries, Emily Joyce, Dan Kapner, Chase W King, Josh D […]


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Sweeps in space: leveraging geographic data to identify beneficial alleles in Anopheles gambiae

Posted by dbos Columbia

Kavli Affiliate: Scott Small | Authors: Clara T Rehmann, Scott T Small, Peter L Ralph and Andrew D. Kern | Summary: As organisms adapt to environmental changes, natural selection modifies the frequency of non-neutral alleles. For beneficial mutations, the outcome of this process may be a selective sweep, in which an allele rapidly increases in […]


Continue.. Sweeps in space: leveraging geographic data to identify beneficial alleles in Anopheles gambiae

An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes

Posted by dbos UCSF

Kavli Affiliate: Edward Chang | Authors: Elisabetta Furlanis, Min Dai, Brenda Leyva Garcia, Josselyn Vergara, Ana Pereira, Kenneth Pelkey, Thien Tran, Bram L. Gorissen, Anna Vlacho, Ariel Hairston, Shuhan Huang, Deepanjali Dwivedi, Sarah Du, Sara Wills, Justin McMahon, Anthony T. Lee, Edward F. Chang, Taha Razzaq, Ahmed Qazi, Geoffrey Vargish, Xiaoqing Yuan, Adam Caccavano, Steven […]


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Synaptic Spine Head Morphodynamics from Graph Grammar Rules for Actin Dynamics

Posted by dbos UCSD / Salk

Kavli Affiliate: Terrence Sejnowski | Authors: Matthew Hur, Thomas Bartol, Padmini Rangamani, Terrence Sejnowski and Eric Mjolsness | Summary: There is a morphodynamic component to synaptic learning by which changes in dendritic (postsynaptic) spine head size are associated with the strengthening or weakening of the synaptic connection between two neurons, in response to the temporal […]


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Decomposed Linear Dynamical Systems (dLDS) models reveal context-dependent dynamic connectivity in C. elegans

Posted by dbos Hopkins

Kavli Affiliate: Adam S. Charles | Authors: Eva Yezerets, Noga Mudrik and Adam Charles | Summary: Mounting empirical evidence indicates that neural “tuning” can be highly variable within an individual across time and especially across individuals. Furthermore, modulatory effects can change the relationship between neurons in the brain as a function of behavioral or other […]


Continue.. Decomposed Linear Dynamical Systems (dLDS) models reveal context-dependent dynamic connectivity in C. elegans

Suite3D: Volumetric cell detection for two-photon microscopy

Posted by klaurent Rockefeller

Kavli Affiliate: Alipasha Vaziri | Authors: Ali Haydaroğlu, Sam Dodgson, Michael Krumin, Andrew Landau, Liad J. Baruchin, Tinya Chang, Jingkun Guo, David Meyer, Charu B. Reddy, Jian Zhong, Na Ji, Sylvia Schröder, Kenneth D. Harris, Alipasha Vaziri and Matteo Carandini | Summary: In two-photon imaging of neuronal activity it is common to acquire 3-dimensional volumes. […]


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