Haplotype-resolved reference genomes of the sea turtle clade unveil ultra-syntenic genomes with hotspots of divergence

Kavli Affiliate: Erich Jarvis | Authors: Larissa S. Arantes, Tom Brown, Diego De Panis, Scott D. Whiting, Erin L. LaCasella, Gabriella A. Carvajal, Adam Kennedy, Deana Edmunds, Blair P. Bentley, Jennifer Balacco, Conor Whelan, Nivesh Jain, Tatiana Tilley, Brian O’Toole, Patrick Traore, Erich D. Jarvis, Oliver Berry, Peter H. Dutton, Lisa M. Komoroske and Camila […]


Continue.. Haplotype-resolved reference genomes of the sea turtle clade unveil ultra-syntenic genomes with hotspots of divergence

Long-term editing of brain circuits in mice using an engineered electrical synapse

Kavli Affiliate: Kay Tye | Authors: Elizabeth Ransey, Gwenaëlle Thomas, Elias Wisdom, Agustin Almoril-Porras, Ryan Bowman, Elise Adamson, Kathryn K Walder-Christensen, Jesse A White, Dalton N Hughes, Hannah Schwennesen, Caly Ferguson, Kay Tye, Stephen D Mague, Long-Gang Niu, Zhao-Wen Wang, Daniel Colón-Ramos, Rainbo Hultman, Nenad Bursac and Kafui Dzirasa | Summary: Electrical signaling across distinct […]


Continue.. Long-term editing of brain circuits in mice using an engineered electrical synapse

ATG2A engages Rab1a and ARFGAP1 positive membranes during autophagosome biogenesis

Kavli Affiliate: Pietro De Camilli | Authors: Hui Wang, Matthew Kazaleh, Rachel A. Gioscia-Ryan, Jessica Millar, Gerard Temprano-Sagrera, Sherri Wood, Fran Van Den Burgh, Muriel G Blin, Kathleen M Wragg, Adrain Luna, Robert Bruce Hawkins, Scott A Soleimanpour, Maria Sabater-Lleal, Chang Shu, Daniel A Beard, Gorav Ailawadi, Jane C Deng, Daniel R Goldstein and Morgan […]


Continue.. ATG2A engages Rab1a and ARFGAP1 positive membranes during autophagosome biogenesis

Deficiency of mitophagy mediator Parkin in aortic smooth muscle cells exacerbates abdominal aortic aneurysm

Kavli Affiliate: Robert Hawkins | Authors: Hui Wang, Matthew Kazaleh, Rachel A. Gioscia-Ryan, Jessica Millar, Gerard Temprano-Sagrera, Sherri Wood, Fran Van Den Burgh, Muriel G Blin, Kathleen M Wragg, Adrain Luna, Robert Bruce Hawkins, Scott A Soleimanpour, Maria Sabater-Lleal, Chang Shu, Daniel A Beard, Gorav Ailawadi, Jane C Deng, Daniel R Goldstein and Morgan Salmon […]


Continue.. Deficiency of mitophagy mediator Parkin in aortic smooth muscle cells exacerbates abdominal aortic aneurysm

Accessible, realistic genome simulation with selection using stdpopsim

Kavli Affiliate: Scott Small | Authors: Graham Gower, Nathaniel S. Pope, Murillo F. Rodrigues, Silas Tittes, Linh N. Tran, Ornob Alam, Maria Izabel Alves Cavassim, Peter D. Fields, Benjamin C. Haller, Xin Huang, Ben Jeffrey, Kevin Korfmann, Christopher C. Kyriazis, Jiseon Min, Ines Rebollo, Clara T Rehmann, Scott T. Small, Christopher C. R. Smith, Georgia […]


Continue.. Accessible, realistic genome simulation with selection using stdpopsim

CellBouncer, A Unified Toolkit for Single-Cell Demultiplexing and Ambient RNA Analysis, Reveals Hominid Mitochondrial Incompatibilities

Kavli Affiliate: Alex Pollen | Authors: Nathan K Schaefer, Bryan J Pavlovic and Alex Aaron Pollen | Summary: Pooled processing, in which cells from multiple sources are cultured or captured together, is an increasingly popular strategy for droplet-based single cell sequencing studies. This design allows efficient scaling of experiments, isolation of cell-intrinsic differences, and mitigation […]


Continue.. CellBouncer, A Unified Toolkit for Single-Cell Demultiplexing and Ambient RNA Analysis, Reveals Hominid Mitochondrial Incompatibilities

Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant (Ooceraea biroi)

Kavli Affiliate: Daniel Kronauer | Authors: Kip D Lacy, Jina Lee, Kathryn Rozen-Gagnon, Wei Wang, Thomas S Carroll and Daniel J C Kronauer | Summary: Sex determination is a developmental switch that triggers sex-specific developmental programs. This switch is flipped by the expression of genes that promote male- or female-specific development. Many lineages have evolved […]


Continue.. Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant (Ooceraea biroi)

Prophages as a source of antimicrobial resistance genes in the human microbiome

Kavli Affiliate: Robert Edwards | Authors: Laura K Inglis, Michael J Roach, Susanna R Grigson and Robert A. Edwards | Summary: Prophages—viruses that integrate into bacterial genomes—are ubiquitous in the microbial realm. Prophages contribute significantly to horizontal gene transfer, including the potential spread of antimicrobial resistance (AMR) genes, because they can collect host genes. Understanding […]


Continue.. Prophages as a source of antimicrobial resistance genes in the human microbiome

Heterocellular and homocellular electrically coupled networks of the thalamus and cortex revealed by focal photomapping

Kavli Affiliate: Kevin Bender | Authors: Mitchell J. Vaughn, Kevin J. Bender and Julie S. Haas | Summary: Electrical synapses are present widely across the mammalian brain and are crucial components of active neural circuitry and connectomes. Identification of electrically coupled networks in living tissue has been limited by technical demands of multiplexed recordings, and […]


Continue.. Heterocellular and homocellular electrically coupled networks of the thalamus and cortex revealed by focal photomapping

Distinct representations of an anxiogenic environment in different cell types of the ventral hippocampus

Kavli Affiliate: Stefano Fusi and René Hen | Authors: Jack E Berry, Jessica C Jimenez, Wei-Li Chang, Kenechukwu Michael Ogbu, Nicholas Manfred, Karly Tegang, Stefano Fusi, René Hen and Clay Lacefield | Summary: In addition to its role in episodic memory and spatial navigation, the hippocampus has also been found to influence mood-related disorders such […]


Continue.. Distinct representations of an anxiogenic environment in different cell types of the ventral hippocampus