Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Muller glia.

Posted by dbos Hopkins

Kavli Affiliate: Seth Blackshaw | Authors: Nguyet Le, Sherine Awad, Isabella Palazzo, Thanh Hoang and Seth Blackshaw | Summary: Retinal Müller glia in cold-blooded vertebrates can reprogram into neurogenic progenitors to replace neurons lost to injury, but mammals lack this ability. While recent studies have shown that transgenic overexpression of neurogenic bHLH factors and glial-specific […]


Continue.. Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Muller glia.

Accept-reject decision-making revealed via a quantitative and ethological study of C. elegans foraging

Posted by dbos UCSD / Salk

Kavli Affiliate: Sreekanth Chalasani | Authors: Jessica A Haley, Tianyi Chen, Mikio Aoi and Sreekanth H Chalasani | Summary: Decision-making is a ubiquitous component of animal behavior that is often studied in the context of foraging. Foragers make a series of decisions while locating food (food search), choosing between food types (diet or patch choice), […]


Continue.. Accept-reject decision-making revealed via a quantitative and ethological study of C. elegans foraging

Hardware-efficient quantum error correction using concatenated bosonic qubits

Posted by dbos Caltech

Kavli Affiliate: Oskar Painter | First 5 Authors: Harald Putterman, Kyungjoo Noh, Connor T. Hann, Gregory S. MacCabe, Shahriar Aghaeimeibodi | Summary: In order to solve problems of practical importance, quantum computers will likely need to incorporate quantum error correction, where a logical qubit is redundantly encoded in many noisy physical qubits. The large physical-qubit […]


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First Resolution of Microlensed Images of a Binary-Lens Event

Posted by dbos Peking

Kavli Affiliate: Subo Dong | First 5 Authors: Zexuan Wu, Subo Dong, A. Mérand, Christopher S. Kochanek, Przemek Mróz | Summary: We resolve the multiple images of the binary-lens microlensing event ASASSN-22av using the GRAVITY instrument of the Very Large Telescope Interferometer (VLTI). The light curves show weak binary perturbations, complicating the analysis, but the […]


Continue.. First Resolution of Microlensed Images of a Binary-Lens Event

First Resolution of Microlensed Images of a Binary-Lens Event

Posted by Peking

Kavli Affiliate: Jinyi Shangguan | First 5 Authors: Zexuan Wu, Subo Dong, A. Mérand, Christopher S. Kochanek, Przemek Mróz | Summary: We resolve the multiple images of the binary-lens microlensing event ASASSN-22av using the GRAVITY instrument of the Very Large Telescope Interferometer (VLTI). The light curves show weak binary perturbations, complicating the analysis, but the […]


Continue.. First Resolution of Microlensed Images of a Binary-Lens Event

Quantum resources of quantum and classical variational methods

Posted by dbos Delft

Kavli Affiliate: Eliska Greplova | First 5 Authors: Thomas Spriggs, Arash Ahmadi, Bokai Chen, Eliska Greplova, | Summary: Variational techniques have long been at the heart of atomic, solid-state, and many-body physics. They have recently extended to quantum and classical machine learning, providing a basis for representing quantum states via neural networks. These methods generally […]


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Chiral superfluidity of helium-3 in the quasi-two-dimensional limit

Posted by dbos Cornell

Kavli Affiliate: Jeevak M. Parpia | First 5 Authors: Petri J. Heikkinen, Lev V. Levitin, Xavier Rojas, Angadjit Singh, Nathan Eng | Summary: Anisotropic pair breaking close to surfaces favors chiral superfluid $^3$He-A over time-reversal invariant $^3$He-B. Confining superfluid $^3$He into a cavity of height $D$ of the order of the Cooper pair size characterized […]


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Transdisciplinary collaborations for advancing sustainable and resilient agricultural systems

Posted by dbos Cornell

Kavli Affiliate: Abraham Stroock | First 5 Authors: Vesna Bacheva, Imani Madison, Mathew Baldwin, Mark Beilstein, Douglas F. Call | Summary: Feeding the growing human population sustainably amidst climate change is one of the most important challenges in the 21st century. Current practices often lead to the overuse of agronomic inputs, such as synthetic fertilizers […]


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Improving constraints on the extended mass distribution in the Galactic Center with stellar orbits

Posted by Peking

Kavli Affiliate: Jinyi Shangguan | First 5 Authors: The GRAVITY Collaboration, Karim Abd El Dayem, Roberto Abuter, Nicolas Aimar, Pau Amaro Seoane | Summary: Studying the orbital motion of stars around Sagittarius A* in the Galactic Center provides a unique opportunity to probe the gravitational potential near the supermassive black hole at the heart of […]


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Lateral prefrontal cortex controls interplay between working memory and actions

Posted by dbos UCSD / Salk

Kavli Affiliate: Anastasia Kiyonaga | Authors: Anastasia Kiyonaga, Jacob Miller and Mark D’Esposito | Summary: Humans must often keep multiple task goals in mind, at different levels of priority and immediacy, while also interacting with the environment. We might need to remember information for an upcoming task while engaged in more immediate actions. Consequently, actively […]


Continue.. Lateral prefrontal cortex controls interplay between working memory and actions