Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Robert Edwards | Authors: George Bouras, Sung.won Lim, Lindsay Durr, Sarah Vreugde, Alexander Goesmann, Robert A Edwards and Oliver Schwengers | Summary: The functional annotation of protein sequences has undergone tremendous progress over recent years, but still too-many protein sequences […]

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Xin Duan | Authors: Wenhao Shang, Guiying Hong, William E Keller, Ryan A Morton, Pierre Zeboulon, Toma Kenichi, Xin Duan, Douglas B Gould and Tyson N Kim | Summary: The neurosensory retina is one of the most metabolically active tissues […]

Kavli Affiliate: Graeme Davis | Authors: Peter H. Chipman, Richard D. Fetter, Forrest J. Ragozzino, Unghwi Lee and Graeme W. Davis | Summary: Presynaptic homeostatic plasticity (PHP) is a potent form of homeostatic plasticity that has been documented at synapses as diverse as the glutamatergic Drosophila neuromuscular junction (NMJ), cholinergic mammalian NMJ (including human), and […]

Kavli Affiliate: Xin Duan, Lily Jan | Authors: Tongfei A. Wang, Chao Chen, Ruogu Liu, Aijia Yi-Luo, Xiaoyan Cao, Jitao Hu, Shikang Guan, Si-yuan Chang, Xiaoli Cui, Wei Zhou, Fei Zhao, Chun-Teng Huang, Xin Duan and Lily Y. Jan | Summary: The brain coordinates animal physiology and behavior via neuronal circuits. To understand and simulate […]

Kavli Affiliate: Alex Pollen | Authors: Alyssa M Yoxsimer, Rhea R Daugherty, Emily E Hare, Yingguang Frank Chan, Felicity C Jones, Garrett A Roberts Kingman, Emma G Offenberg, Timothy R Howes, Haili Zhang, Alex Aaron Pollen, Shannon D Brady, Kathleen T Xie, Heidi I Chen, Craig B Lowe, Eric H Au, Jane Grimwood, Jeremy Schmutz, […]

Kavli Affiliate: Daniel Minor | Authors: Sandra Zakrzewska, Zhou Chen, Elizabeth Park, Roshni G Bhaskar, T. Aaron Bedell, J Du Bois and Daniel L Minor, Jr. | Summary: Saxitoxin (STX) and its congeners (paralytic shellfish toxins, PSTs) are among the most potent small-molecule toxins. PSTs are produced by harmful algal blooms and derive toxicity by […]

Kavli Affiliate: Adam Gazzaley | Authors: Andrew C Heusser, Tony J Simon, Esther Elliot, Christopher James, Adam Gazzaley and Nicole Gibson | Summary: Background Emotion regulation—the ability to respond to and restore equilibrium after emotional perturbations—is central to mental health. Yet objective measurement remains limited to lab-based studies with group-level results, while consumer wearables focus […]

Kavli Affiliate: Mazen Kheirbek | Authors: Joshua X Bratsch-Prince, Mingyang Wei, Srutika Sureshbabu, Vivan Chhaya, Nuria Cano Adamuz, Kelsey Logas and Mazen Kheirbek | Summary: In uncertain, threatening environments, rapid and flexible behavioral decisions are essential for survival. The ventral CA1 region of the hippocampus encodes threatening contexts and can regulate avoidance-related behaviors. While activity […]

Kavli Affiliate: Roger Nicoll | Authors: tianli dou, junting zhang, yidan hong, xiumin chen and roger nicoll | Summary: Excitatory glutamatergic synapses in the brain are remarkably plastic. Two forms of plasticity have received the most attention: long-term potentiation (LTP) and synaptic homeostasis. While LTP requires the activation of NMDA receptors, synaptic homeostasis does not. […]

Kavli Affiliate: Zachary Knight | Authors: Truong Ly, Xinyang Yi, Grace R. Lee, James CR Grove, Youssef E. Sibih, Yun Y. Oh, Longhui Qiu, Nilla Sivakumar and Zachary A Knight | Summary: The termination of a meal is triggered by sensory feedback from the stomach and intestines that reports on ingested food1–10 and is relayed […]