Semaphorin 3A promotes resilience of sleep and cognition to brain injury

Kavli Affiliate: Jeanne Paz | Authors: Deanna Necula, Yuliya Voskobiynyk, Srujana Poluri and Jeanne T. Paz | Summary: Chronic sleep disruption and cognitive deficits are debilitating long-term consequences of traumatic brain injury (TBI), yet the endogenous mechanisms that drive network-level recovery remain poorly understood. Here, we demonstrate that during the chronic phase post-injury, network oscillations […]


Continue.. Semaphorin 3A promotes resilience of sleep and cognition to brain injury

A Neuroendocrine Circuit That Suppresses Excretion and Pelvic Pain During Activity

  Kavli Affiliate: Xin Duan | Authors: Lucas E Cabrera-Zapata, Archana Venkataraman, Andrea M Harrington, Jitao Hu, Fernanda Castro-Navarro, Kristina Galatsis, Xin Duan, Stuart M Brierley, Kimberly Keil Stietz and Holly A. Ingrahamber | Summary: Mate-seeking during peak sexual receptivity is tightly coupled with exploratory movement, a process made more efficient by transient suppression of […]


Continue.. A Neuroendocrine Circuit That Suppresses Excretion and Pelvic Pain During Activity

Parallel Opposing GABAergic Pallidothalamic Pathways

  Kavli Affiliate: Jeanne Paz | Authors: Isaac Y.M. Chang and Jeanne T. Paz | Summary: Coordinated movement relies on interactions between the basal ganglia and the thalamus, yet the circuits linking these structures are not fully understood. Here, we dissect a non-canonical basal ganglia output pathway, from the external globus pallidus (GPe) to the […]


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State-Dependent Organization of Microscale Functional Circuitry in Visual Cortex

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Reza Abbasi Asl | Authors: Rahul Biswas, Hasika Wickrama Senevirathne, Yujing Wang, Jiang Zhang, Somabha Mukherjee and Reza Abbasi-Asl | Summary: How the cortex organizes directed functional interactions among individual neurons and how this microscale circuitry maps onto cell types […]


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Single-library chromosome-scale diploid assemblies of vole genomes resolve a species-specific duplication implicated in pair bonding

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Devanand Manoli | Authors: Mohamed Abuelanin, Gulhan Kaya, Juniper A Lake, Christine Lambert, Melody V Wu, Kristen Berendzen, Ksenia Krasheninnikova, Jonathan MD Wood, Nancy G Solomon, Zoe R Donaldson, Karen L Bales, Kerstin Howe, Jonas Korlach, Devanand S Manoli, Jessica […]


Continue.. Single-library chromosome-scale diploid assemblies of vole genomes resolve a species-specific duplication implicated in pair bonding

Disruption of theta-timescale spiking impairs learning but spares hippocampal replay

Kavli Affiliate: Loren Frank | Authors: Abhilasha Joshi, Alison E. Comrie, Samuel Bray, Abhijith Mankili, Jennifer A. Guidera, Rhino Nevers, Xulu Sun, Emily Monroe, Viktor Kharazia, Ryan Ly, Daniela Astudillo Maya, Denisse Morales-Rodriguez, Jai Yu, Anna Kiseleva, Victor Perez and Loren M. Frank | Summary: The ability to rapidly learn and retrieve salient information about […]


Continue.. Disruption of theta-timescale spiking impairs learning but spares hippocampal replay

A multimodal interrogation of Broca’s area in the pediatric and adult human brain

Kavli Affiliate: Arturo Alvarez-Buylla, Arnold R. Kriegstein and David Rowitch | Authors: Juan Moriano, Tanzila Mukhtar, Jimmy Tsz Hang Lee, Fani Memi, Jonathan Augustin, Rachel Leonard, Joseph Asfouri, I-Ling Lu, Clara Siebert, Jennifer Ja-Yoon Choi, Guolong Zuo, Yinshui Chang, Stanislaw Makarchuk, Elina Jin, Martin Prete, Shaohui Wang, Qiuli Bi, Yuhan Hao, Liz Tuck, Katy Tudor, […]


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Device-embedded accelerometry complements neural signals for tracking parkinsonian motor states

Kavli Affiliate: Philip Starr | Authors: TAO LIU, Jiaang Yao, Bahman Abdi-Sargezeh, Abhinav Sharma, Camille Lasbareilles, Robert Tsi Lok Ho, Jackson Cheung, Timothy Denison, Huiling Tan, Wolf-Julian Neumann, Minghan Max Zhu, Sebastian Liu, Philip Starr, Simon Little and Ashwini Oswal | Summary: Adaptive deep brain stimulation (aDBS) relies on physiological biomarkers to infer motor state […]


Continue.. Device-embedded accelerometry complements neural signals for tracking parkinsonian motor states

Psilocybin selectively rescues cognitive flexibility impairments caused by aberrant prefrontal error signalin

Kavli Affiliate: Vikaas Sohal | Authors: Christine Liu, Ellie M Ho, Alexander S Enos, Urte Beatrice Baublyte, Isabel M Luna, Alexander R Kosche and Vikaas S Sohal | Summary: Psychedelic drugs show remarkable potential for treating psychiatric disorders, but the mechanisms underlying their therapeutic effects remain relatively unknown. Here, we demonstrate that psilocybin can powerfully […]


Continue.. Psilocybin selectively rescues cognitive flexibility impairments caused by aberrant prefrontal error signalin

Opposing GIPR brainstem circuits differentially control feeding behaviour

Kavli Affiliate: Zachary Knight | Authors: Natalie S Figueredo Burgos, Alejandro Lopez-Cruz, Cecilia Skoug, Anna G Roberts, Kathryn Xie, Iona Davies, Norio Harada, Nobuya Inagaki, Frank Reimann, Fiona M Gribble, Ben Jones, Daniel I Brierley, Stefan Trapp, Zachary A Knight and Alice E Adriaenssens | Summary: Central glucose-dependent insulinotropic polypeptide receptor (GIPR) signalling is required […]


Continue.. Opposing GIPR brainstem circuits differentially control feeding behaviour