Kavli Affiliate: Peter Walter | Authors: Udit Dalwadi, Advait Subramanian, Aniliese Deal, Julia Conrad, Meera Venkatesh, Morgane Boone, Pascal Egea, Lingjie He, Nimit Jain, John D Lee, Yuwei Liu, Lucas Reineke, Kazuki Saito, Nathaniel Talledge, Hannah Toutkoushian, Maxence Le Vasseur, Francesca Zappa, Raoul de Groot, Diego Acosta-Alvear, Christopher Arthur, Jodi Nunnari, Mauro Costa-Mattioli, James Crawford, […]
Kavli Affiliate: Loren Frank | Authors: Abhilasha Joshi, Alison E. Comrie, Samuel Bray, Abhijith Mankili, Jennifer A. Guidera, Rhino Nevers, Xulu Sun, Emily Monroe, Viktor Kharazia, Ryan Ly, Daniela Astudillo Maya, Denisse Morales-Rodriguez, Jai Yu, Anna Kiseleva, Victor Perez and Loren M. Frank | Summary: The ability to rapidly learn and retrieve salient information about […]
Kavli Affiliate: Robert Edwards | Authors: Vijini Mallawaarachchi, George Bouras, Ryan R. Wick, Susanna R. Grigson, Bhavya Papudeshi and Robert A. Edwards | Summary: Assembly graphs are a fundamental data structure used by genome and metagenome assemblers to represent sequences and their overlap information, facilitating the assembler to construct longer genomic fragments. Apart from their […]
Kavli Affiliate: Jeremy Willsey | Authors: Alyssa Puno, Wojciech M Michno, Li Li, Amanda Everitt, Kate McCluskey, Saw Htun, Dhriti Nagar, Jong Bin Choi, Yuqin Dai, Seyeon Park, Emily Gurwitz, Jeremy Willsey, Fikri Birey and Anca M Pasca | Summary: Extremely preterm birth (at < 28 postconceptional weeks) leads to brain injury and represents the […]
Kavli Affiliate: Vikaas Sohal | Authors: Aarron Justin Phensy, Lara Louise Hagopian, Caitriona M. Costello, Simon Haziza, Omkar Ghenand, Yanping Zhang, Mark J. Schnitzer and Vikaas Singh Sohal | Summary: Cognitive dysfunction in conditions such as schizophrenia involves disrupted communication between the prefrontal cortex (PFC) and mediodorsal thalamus (MD). Parvalbumin interneurons (PVI) are known to […]
Kavli Affiliate: Seth Shipman | Authors: Linhan Wang, Nikolaos Poulis, Deepak Srivastava and Seth Shipman | Summary: Genetically encoded DNA recorders convert transient biological events into stable genomic mutations, offering a means to reconstruct past cellular states. However, current approaches to log historical events by modifying genomic DNA have limited capacity to record the magnitude […]
Kavli Affiliate: Lily Jan and Yuh Nung Jan | Authors: Xiaofan Zhang, Wei Chen, Yayu Wang, Xun Tu, Xiangyu Zhang, Ronald L. Davis, Lily Yeh Jan and Yuh Nung Jan | Summary: ABSTRACT Neuronal remodeling is essential for sculpting neural circuits, and its disruption has been implicated in neurodevelopmental and neuropsychiatric disorders. Yet the molecular […]
Kavli Affiliate: Alex Pollen | Authors: Sara Nolbrant, Jenelle L. Wallace, Jingwen Ding, Tianjia Zhu, Jess L. Sevetson, Janko Kajtez, Isabella A. Baldacci, Emily K. Corrigan, Kaylynn Hoglin, Reed McMullen, Matthew T. Schmitz, Arnar Breevoort, Dani Swope, Fengxia Wu, Bryan J. Pavlovic, Sofie R. Salama, Agnete Kirkeby, Hao Huang, Nathan K. Schaefer and Alex A. […]
Kavli Affiliate: Philip Starr | Authors: Abhinav Sharma, Bahman Abdi Sargezeh, Amelia Hahn, Maria Shcherbakova, Wolf Julian Neumann, Simon Little, Philip Starr and Ashwini Oswal | Summary: Background: Bradykinesia in Parkinson′s disease (PD) may arise due to transient, network–wide neural dynamics that extend beyond beta–band oscillatory activity within the motor cortical-subthalamic nucleus (STN) circuit. Methods: […]
Kavli Affiliate: Daniele Canzio and Stavros Lomvardas | Authors: Martin Escamilla-del-Arenal, Rachel Duffie, Hani Shayya, Valentina Loconte, Axel Ekman, Lena Annika Street, Adan Horta, Daniele Canzio, Kevin Monahan, Carolyn A Larabell, Marko Jovanovic and Stavros Lomvardas/p> | Summary: Diverse epigenetic regulatory mechanisms ensure and regulate cellular diversity. Among others, the histone 3 lysine 9 me3 […]