UCSF – Page 10 – Kavli Institute Pre-Print Publications

Shared Maturation Pathways of HIV-1 Envelope-reactive V3-glycan bnAb Lineages in Human and Rhesus Macaque

Posted by dbos January 30, 2026February 10, 2026UCSF

Kavli Affiliate: Robert Edwards | Authors: Matthew Clark, Hui Li, Mitchell Martin, Tyler Evangelous, Sophie Gobeil, Madison Berry, Kshitij Wagh, Elena Giorgi, Michael Hogarty, Chengyan Zhao, Shuyi Wang, Lorie Marchitto, Wenge Ding, Younghoon Park, Juliette Rando, John Carey, Andrew Connell, Ashwin Skelly, Yue Chen, Seth Rohr, Chuancang Jiang, Sravani Venkatayogi, Katayoun Mansouri, Robert J. Edwards, […]

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Nanoscale Protonation Limits and Charge Density in Polymer Films Govern the Activity of Immobilized LacZ under Acid Stress

Posted by dbos January 29, 2026February 10, 2026UCSF

Kavli Affiliate: Yifan Cheng | Authors: Huida Duan, Junxing Chen, Felicia Fianu, Wei Sun and Yifan Cheng | Summary: Under acidic conditions, polycationic polymer coatings function as protective immobilization supports through protonation-mediated local pH buffering. However, it remains unclear how polymer support design parameters, such as film thickness and charge density, govern that vital protonation […]

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Spyglass: a data analysis framework for reproducible and shareable neuroscience research

Posted by dbos January 29, 2026February 10, 2026UCSF

Kavli Affiliate: Loren Frank | Authors: Kyu Hyun Lee, Eric L. Denovellis, Ryan Ly, Jeremy Magland, Jeff Soules, Alison E Comrie, Daniel P Gramling, Jennifer A Guidera, Rhino Nevers, Philip Adenekan, Chris Brozdowski, Samuel R Bray, Emily Monroe, Ji Hyun Bak, Michael Coulter, Xulu Sun, Emrey Broyles, Donghoon Shin, Sharon Chiang, Cristofer Holobetz, Andrew Tritt, […]

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The mood stabilizer lithium alters behaviour and physiology via the gut brain axis

Posted by dbos January 27, 2026February 10, 2026UCSF

Kavli Affiliate: Robert Edwards | Authors: Daniel William Thorpe, Yoichiro Ootsuka, Rochelle A Peterson, Lauren A Jones, Adam Humenick, Alyce M Martin, Jett Zivkovic, Junichi Sakaguchi, Jack McArdle, Arne Ittner, Simon J Brookes, Ali Habib, Rata Sirimaharaj, Youssef Tawodros, Michael J. Roach, Robert A Edwards, Hans Clevers, Joep Beumer, Jens Puschof, Lai Wei, Rajan Singh, […]

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Single-Cell Raman Profiling Enables Rapid Precision Phage Therapy Against Multidrug-Resistant Hypervirulent Klebsiella pneumoniae

Posted by dbos January 26, 2026February 10, 2026Columbia, UCSF

Kavli Affiliate: Wei Min | Authors: Beimin Liu, Chao Wang, Qingyang Zeng, Min Wei, Weilai Lu, Xueyan Gao, Jing Wan, Jie Feng and Yu Vincent Fu | Summary: Multidrug-resistant hypervirulent Klebsiella pneumoniae (MDR-hvKP) poses a severe global health threat. Phage therapy is a promising alternative, but requires precise matching of phage to the bacterial strain. […]

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A Physics-based Model Reveals Mechanisms of Epigenetic Memory

Posted by dbos January 22, 2026February 4, 2026UCSF

Kavli Affiliate: Hana El-Samad | Authors: Erik J. Navarro, William Poole, Ariane Lismer, Jieqiong Qu, Ioannis Kafetzopoulos, Aled Parry, Jannat Ijaz, Alice Santambrogio, Ryan Spangler, Francisco M. Martin-Zamora, Ken Raj, Wolf Reik, Hana El-Samad, Carlos F. Lopez and Simone Bianco | Summary: In multi-cellular eukaryotic organisms, cell type and specific functional identity are defined by […]

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Degraded ecosystem soil and type 2 diabetes gut microbiomes share altered potential metabolism for sugars, lignin and branched-chain fatty acids: a blind spot for global health?

Posted by dbos January 20, 2026February 4, 2026UCSF

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Robert Edwards | Authors: Craig Liddicoat, Bart A Eijkelkamp, Timothy R Cavagnaro, Jake M Robinson, Kiri Joy Wallace, Andrew D Barnes, Garth Harmsworth, Damien J Keating, Robert A Edwards and Martin F Breed | Summary: The global rise in human […]

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NPEPPS segmental duplication drives position effect expression of TBC1D3 in the human brain

Posted by dbos January 15, 2026February 4, 2026UCSF

Kavli Affiliate: Alex Pollen | Authors: Xavi Guitart, Jessie W. Brunner, Luyao Ren, Hyeonsoo Jeong, DongAhn Yoo, David Porubsky, Mitchell R. Vollger, Kendra Hoekzema, Katherine M. Munson, Kaitlyn Sun, Marcelo Ayllon, Kaylynn Hoglin, Reed McMullen, Bryan Pavlovic, Alex Aaron Pollen and Evan E Eichler | Summary: In humans, the TBC1D3 gene family is thought to […]

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Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice

Posted by dbos January 13, 2026February 4, 2026UCSF

Kavli Affiliate: Jeanne Paz | Authors: Hayk Davtyan, Sarah Naguib, Yuliya Voskobiynyk, Jean Paul Chadarevian, Joia K. Capocchi, Jeannie L. Giacchino, Ghazaleh Eskandari-Sedighi, Vivianna Denittis, Jeremy Ford, Ani Agababian, Jasmine Nguyen, Alina Chadarevian, Madison Sutherland, Sepideh Kiani Shabestari, Alissa Nanali, Jiasheng Zhang, Salvatore Spina, Man Ying Wong, Lea Tenenholz Grinberg, William W Seeley, Eric Huang, […]

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Scalable high-fidelity human vascularized cortical assembloids recapitulate neurovascular co-development and cell specialization

Posted by dbos January 10, 2026January 26, 2026UCSF

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Arnold R. Kriegstein and Edward Chang | Authors: Shubhang Bhalla, Belda Gulsuyu, Damian Sanchez, Jayden M Ross, Santhosh Arul, Adnan Gopinadhan, Muhammet Ozturk, Tanzila Mukhtar, Jonathan J Augustin, Jerry C Wang, Joseph Kim, Chang N Kim, Sena Oten, Yohei Rosen, […]

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