Age-related morphological changes in the C57BL/6J mouse calvaria: implications for stereotaxic neurosurgery

Kavli Affiliate: Zachary Knight | Authors: Zachary A Knight and Heeun Jang | Summary: The mouse skull serves as the coordinate framework for stereotaxic neurosurgery, yet whether aging alters surgically critical calvarial geometry has not been examined. We measured three parameters in large cohorts of young (2-3 months) and aged (23-30 months) male and female […]


Continue.. Age-related morphological changes in the C57BL/6J mouse calvaria: implications for stereotaxic neurosurgery

Meta-learning is expressed through altered prefrontal cortical dynamics

Kavli Affiliate: Joshua Berke, Loren Frank, and Razi Haque | Authors: Xulu Sun, Alison E. Comrie, Ari E. Kahn, Emily J. Monroe, Clayton B. Washington, Abhilasha Joshi, Jennifer A. Guidera, Eric L. Denovellis, Timothy A. Krausz, Jenny Zhou, Paige Thompson, Jose Hernandez, Allison Yorita, Razi Haque, Chethan Pandarinath, Joshua D. Berke, Nathaniel D. Daw and […]


Continue.. Meta-learning is expressed through altered prefrontal cortical dynamics

Morphogenetic Patterning During Regional and Cell Type Specification in the Embryonic Basal Ganglia

Kavli Affiliate: John Rubenstein | Authors: Jia Sheng Hu, Karol Cichewicz, Jonathan W.C. Lim, Linda J Richards, Luis Puelles, Alex S Nord and John L.R. Rubenstein | Summary: Cell type specification in the embryonic brain and spinal cord is thought to begin within molecularly defined progenitor domains that do not intermix. Our data provide an […]


Continue.. Morphogenetic Patterning During Regional and Cell Type Specification in the Embryonic Basal Ganglia

Lung adventitial fibroblasts support type 2 Tregs to shape the response to influenza infection

Kavli Affiliate: Anna Molofsky | Authors: Anthony Chang, Joanna Balcerek, Sofia Caryotakis, Kennedi Pyper, Peri Matatia, Elina Wells, Tatsuya Tsukui, Nathan A Ewing-Crystal, Eric Dean Merrill, Nicholas M Mroz, Madelene W Dahlgren, Kelly Cautivo, Marcela Taruselli, Hiromi Nakao-Inoue, Anna V Molofsky, Dean Sheppard and Ari B Molofsky | Summary: Viral pneumonias are lung infections that […]


Continue.. Lung adventitial fibroblasts support type 2 Tregs to shape the response to influenza infection

Tau-induced mitochondrial reverse electron transport drives neurodegeneration

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Su Guo | Authors: Wen Li, Suman Rimal, Sunil Bhurtel, Lucas Yeung, Benjamin Lu, Lea T Grinberg, Salvatore Spina, Inma Cobos, William W Seeley, Su Guo and Bingwei Lu | Summary: Hyperphosphorylation and aggregation of the microtubule-associated protein tau are […]


Continue.. Tau-induced mitochondrial reverse electron transport drives neurodegeneration

Molecular dynamics of Brodmann Area 22 in development and autism

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Edward Chang | Authors: Varun Suresh, Emilie M Wigdor, Yuhan Hao, Rachel Leonard, Joseph Asfouri, Micheal Griffiths, Clements Evans, Guohua Yuan, Narjes Rohani, Jakob Weiss, Chimmi Dema, Tanzila Mukhthar, Frederik Lassen, Nicole Schafer, Shan Dong, Duncan S Palmer, Edward F […]


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Baktfold: Sensitive protein functional annotation across the microbial tree of life using structural information

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Robert Edwards | Authors: George Bouras, Sung.won Lim, Lindsay Durr, Sarah Vreugde, Alexander Goesmann, Robert A Edwards and Oliver Schwengers | Summary: The functional annotation of protein sequences has undergone tremendous progress over recent years, but still too-many protein sequences […]


Continue.. Baktfold: Sensitive protein functional annotation across the microbial tree of life using structural information

A Three-dimensional Analytical Framework for Retinal Microvasculature Reveals Layer-associated Vulnerability in Development and Neovascular Remodeling

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Xin Duan | Authors: Wenhao Shang, Guiying Hong, William E Keller, Ryan A Morton, Pierre Zeboulon, Toma Kenichi, Xin Duan, Douglas B Gould and Tyson N Kim | Summary: The neurosensory retina is one of the most metabolically active tissues […]


Continue.. A Three-dimensional Analytical Framework for Retinal Microvasculature Reveals Layer-associated Vulnerability in Development and Neovascular Remodeling

Robust PHP in Adult Hippocampus: Essential Assay Optimizations

Kavli Affiliate: Graeme Davis | Authors: Peter H. Chipman, Richard D. Fetter, Forrest J. Ragozzino, Unghwi Lee and Graeme W. Davis | Summary: Presynaptic homeostatic plasticity (PHP) is a potent form of homeostatic plasticity that has been documented at synapses as diverse as the glutamatergic Drosophila neuromuscular junction (NMJ), cholinergic mammalian NMJ (including human), and […]


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WTR: A Toolkit for Functional Anterograde Transsynaptic Circuit Mapping

Kavli Affiliate: Xin Duan, Lily Jan | Authors: Tongfei A. Wang, Chao Chen, Ruogu Liu, Aijia Yi-Luo, Xiaoyan Cao, Jitao Hu, Shikang Guan, Si-yuan Chang, Xiaoli Cui, Wei Zhou, Fei Zhao, Chun-Teng Huang, Xin Duan and Lily Y. Jan | Summary: The brain coordinates animal physiology and behavior via neuronal circuits. To understand and simulate […]


Continue.. WTR: A Toolkit for Functional Anterograde Transsynaptic Circuit Mapping