Kavli Affiliate: Loren Frank | Authors: Joseph Park, Cameron Smith, Shih Yi Tseng, Jennifer Guidera, Andrei V Semenov, Stanislav Smirnov, Loren M Frank and Gerald M Pao | Summary: Complex systems such as brains and other interacting biological and physical processes are difficult to represent because they evolve across many variables, scales, and nonlinear interactions. […]
Kavli Affiliate: Edward Chang | Authors: Samantha M Gray, Adam JO Dede, Zachariah R Cross, Ignacio Saez, Fady Girgis, Edward F Chang, Kurtis Auguste, Ammar Shaikhouni, Robert T Knight and Elizabeth L Johnson | Summary: Working memory (WM) enables us to maintain and manipulate information over time, but how the brain organizes sequential information locally […]
Kavli Affiliate: Kevin Bender | Authors: Elinor Lewis, Jessie Muir, Ling C Li, Madeline King, Kaden Adams, Julianna Glienke, Sarah Warren Gooding, Kevin Bender, Christina Kim and Jennifer Whistler | Summary: Second generation antipsychotics (SGAs) are widely used clinical tools; yet, they often cause negative side effects and take weeks to become effective, leading to […]
Kavli Affiliate: Anna Molofsky | Authors: Sarah R Anderson, Pailin Chiaranunt, Nicholas M Mroz, Sarah D Wade, Fathima N Pitchai, Shinya Okamura, Ashley McDonough, Yi-Je Chen, Ari B Molofsky, Jonathan R Weinstein, Raul Andino and Anna V Molofsky | Summary: Interferons (IFNs) are canonical antiviral cytokines with emerging homeostatic functions across tissues, including in the […]
Kavli Affiliate: Zachary Knight | Authors: Zachary A Knight and Heeun Jang | Summary: The mouse skull serves as the coordinate framework for stereotaxic neurosurgery, yet whether aging alters surgically critical calvarial geometry has not been examined. We measured three parameters in large cohorts of young (2-3 months) and aged (23-30 months) male and female […]
Kavli Affiliate: Joshua Berke, Loren Frank, and Razi Haque | Authors: Xulu Sun, Alison E. Comrie, Ari E. Kahn, Emily J. Monroe, Clayton B. Washington, Abhilasha Joshi, Jennifer A. Guidera, Eric L. Denovellis, Timothy A. Krausz, Jenny Zhou, Paige Thompson, Jose Hernandez, Allison Yorita, Razi Haque, Chethan Pandarinath, Joshua D. Berke, Nathaniel D. Daw and […]
Kavli Affiliate: John Rubenstein | Authors: Jia Sheng Hu, Karol Cichewicz, Jonathan W.C. Lim, Linda J Richards, Luis Puelles, Alex S Nord and John L.R. Rubenstein | Summary: Cell type specification in the embryonic brain and spinal cord is thought to begin within molecularly defined progenitor domains that do not intermix. Our data provide an […]
Kavli Affiliate: Anna Molofsky | Authors: Anthony Chang, Joanna Balcerek, Sofia Caryotakis, Kennedi Pyper, Peri Matatia, Elina Wells, Tatsuya Tsukui, Nathan A Ewing-Crystal, Eric Dean Merrill, Nicholas M Mroz, Madelene W Dahlgren, Kelly Cautivo, Marcela Taruselli, Hiromi Nakao-Inoue, Anna V Molofsky, Dean Sheppard and Ari B Molofsky | Summary: Viral pneumonias are lung infections that […]
Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Su Guo | Authors: Wen Li, Suman Rimal, Sunil Bhurtel, Lucas Yeung, Benjamin Lu, Lea T Grinberg, Salvatore Spina, Inma Cobos, William W Seeley, Su Guo and Bingwei Lu | Summary: Hyperphosphorylation and aggregation of the microtubule-associated protein tau are […]
Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Edward Chang | Authors: Varun Suresh, Emilie M Wigdor, Yuhan Hao, Rachel Leonard, Joseph Asfouri, Micheal Griffiths, Clements Evans, Guohua Yuan, Narjes Rohani, Jakob Weiss, Chimmi Dema, Tanzila Mukhthar, Frederik Lassen, Nicole Schafer, Shan Dong, Duncan S Palmer, Edward F […]