Posterior parietal cortex maps progress along routes sharing the same meta-structure

Kavli Affiliate: Douglas Nitz | Authors: Alexander B Johnson and Douglas A Nitz | Summary: Neurons of posterior parietal cortex were recorded as rats performed a working memory task within a network of intersecting paths. The specific routes utilized in task performance provided opportunity to contrast responses of posterior parietal cortex sub-populations to linear and […]


Continue.. Posterior parietal cortex maps progress along routes sharing the same meta-structure

Missing data approaches for longitudinal neuroimaging research: Examples from the Adolescent Brain and Cognitive Development (ABCD) Study

Kavli Affiliate: Wesley Thompson | Authors: Lin Li, Mohammadreza Bayat, Timothy Hayes, Wesley K. Thompson, Arianna Morgan Sandmark Gard and Anthony Steven Dick | Summary: This paper addresses the challenges of managing missing values within expansive longitudinal neuroimaging datasets, using the specific example of data derived from the Adolescent Brain and Cognitive Development ABCD study. […]


Continue.. Missing data approaches for longitudinal neuroimaging research: Examples from the Adolescent Brain and Cognitive Development (ABCD) Study

Disruption of Core Stress Granule Protein Aggregates Promotes CNS Axon Regeneration

Kavli Affiliate: Mark H. Tuszynski; | Authors: Pabitra K Sahoo, Nick Hanovice, Patricia Ward, Manasi A Agrawal, Terika P Smith, HaoMin SiMa, Jennifer N Dulin, Lauren S Vaughn, Mark Tuszynski, Kristy Welshhans, Larry Benowitz, Arthur English, John D Houle and Jeffery L Twiss | Summary: Depletion or inhibition of core stress granule proteins, G3BP1 in […]


Continue.. Disruption of Core Stress Granule Protein Aggregates Promotes CNS Axon Regeneration

Scalable electron tomography for connectomics

Kavli Affiliate: Mark Ellisman; | Authors: Aaron T Kuan, Sebastien Phan, Keun-Young Kim, Mason Mackey, Minsu Kim, Steven T Peltier, Mark Ellisman and Wei-Chung Allen Lee | Summary: We demonstrate limited-tilt, serial section electron tomography (ET), which can non-destructively map brain circuits over large 3D volumes and reveal high-resolution, supramolecular details within subvolumes of interest. […]


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Behavioral impairments are linked to neuroinflammation in mice with Cerebral Cavernous Malformation disease

Kavli Affiliate: Stephan Anagnostaras; | Authors: Joseph Offenberger, Bianca Chen, Leigh-Ana Rossitto, Irisa Jin, Liam Conaboy, Helios Gallego-Gutierrez, Bliss Nelsen, Eduardo Frias-Anaya, David J. Gonzalez, Stephan Anagnostaras and Miguel Alejandro Lopez-Ramirez | Summary: Background Cerebral Cavernous Malformations (CCMs) are neurovascular abnormalities in the central nervous system (CNS) caused by loss of function mutations in KRIT1 […]


Continue.. Behavioral impairments are linked to neuroinflammation in mice with Cerebral Cavernous Malformation disease

Interdependence between SEB-3 and NLP-49 peptides shifts across predator-induced defensive behavioral modes in Caenorhabditis elegans

Kavli Affiliate: Sreekanth Chalasani | Authors: Kathleen T Quach, Gillian A Hughes and Sreekanth H Chalasani | Summary: Prey must balance the need to avoid predators with the need to feed, a dilemma central to prey refuge theory. Additionally, prey must also assess predatory imminence, or how close predator threats are in space and time. […]


Continue.. Interdependence between SEB-3 and NLP-49 peptides shifts across predator-induced defensive behavioral modes in Caenorhabditis elegans

Coumarin as a general switching auxiliary to prepare photochromic and spontaneously blinking fluorophores

Kavli Affiliate: Timothy Brown | Authors: Fadi Jradi, Brian P English, Timothy A Brown, Jesse Arron, Satya Khuon, James A Galbraith, Catherine G Galbraith and Luke D Lavis | Summary: Single-molecule localization microscopy (SMLM) uses activatable or switchable fluorophores to create non-diffraction limited maps of molecular location in biological samples. Despite the utility of this […]


Continue.. Coumarin as a general switching auxiliary to prepare photochromic and spontaneously blinking fluorophores

Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components using a large adolescent sample

Kavli Affiliate: Anders Dale | Authors: Diana M. Smith, Pravesh Parekh, Joseph Kennedy, Robert J. Loughnan, Oleksandr Frei, Thomas E. Nichols, Ole A. Andreassen, Terry L. Jernigan and Anders M. Dale | Summary: The relative contributions of genetic variation and experience in shaping the morphology of the adolescent brain are not fully understood. Using longitudinal […]


Continue.. Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components using a large adolescent sample

An unbiased method to partition diverse neuronal responses into functional ensembles reveals interpretable population dynamics during innate social behavior

Kavli Affiliate: Kay Tye | Authors: Alexander Lin, Cyril Akafia, Olga Dal Monte, Siqi Fan, Nicholas Fagan, Philip Putnam, Kay M. Tye, Steve Chang, Demba Ba and AZA Stephen Allsop; | Summary: In neuroscience, understanding how single-neuron firing contributes to distributed neural ensembles is crucial. Traditional methods of analysis have been limited to descriptions of […]


Continue.. An unbiased method to partition diverse neuronal responses into functional ensembles reveals interpretable population dynamics during innate social behavior

Dopey-dependent regulation of extracellular vesicles maintains neuronal morphology

Kavli Affiliate: Yishi Jin | Authors: Seungmee Park, Nathaniel Noblett, Lauren Pitts, Antonio Colavita, Ann M Wehman, Yishi Jin and Andrew D Chishol/p> | Summary: Mature neurons maintain their distinctive morphology for extended periods in adult life. Compared to developmental neurite outgrowth, axon guidance, and target selection, relatively little is known of mechanisms that maintain […]


Continue.. Dopey-dependent regulation of extracellular vesicles maintains neuronal morphology