The Role of Macronutrient Composition in Semipurified Diets in Shaping Distinct Obesity Phenotypes: Evidence for Hepatic Oxidative Stress Involvement

Kavli Affiliate: Gabriel Silva | Authors: Pedro Rocha Tenorio, Gabriel Smolak Sobieski e Silva, Isadora Chagas Vercellone, Débora Hipólito Quadreli, Juliany Carolina Duma de Castro, Glaura Scantamburlo Alves Fernandes and Fábio Goulart de Andrade | Summary: While obesity is widely recognized as a global epidemic, the specific roles of food processing and macronutrient composition in […]


Continue.. The Role of Macronutrient Composition in Semipurified Diets in Shaping Distinct Obesity Phenotypes: Evidence for Hepatic Oxidative Stress Involvement

Long-term memory performance optimization via Neural network-based curve fitting in Drosophila

Kavli Affiliate: Ann-Shyn Chiang | Authors: Yung-Ching Lu, Chih-Ying Chen, Ling-Hui Yen, Chi-Lien Yang, Ya-Ding Liu, Wen-Jun Chen, Kuan-Lin Feng, Ming-Chin Wu, Ann-Shyn Chiang, Da-Jeng Yao, Chih-Ming Ho, Shih-Hwa Chiou and Li-An Chu | Summary: Long-term memory (LTM) formation typically requires extensive training or highly salient experiences, limiting learning efficiency. Operant conditioning is generally thought […]


Continue.. Long-term memory performance optimization via Neural network-based curve fitting in Drosophila

Flexible decisions arise from resource-rational memory sampling

Kavli Affiliate: Marcelo Mattar | Authors: Jonathan Nicholas, Sixing Chen and Marcelo G Mattar | Summary: Flexible decision making depends on retrieving and recombining memories. Yet because this process unfolds covertly, its governing principles remain unknown. Here we use gaze reinstatement to uncover the hidden dynamics and computational logic of memory retrieval during flexible behavior. […]


Continue.. Flexible decisions arise from resource-rational memory sampling

Adaptive Charge Modulation Enables Focal, Selective Spinal Cord Stimulation

Kavli Affiliate: Eiman Azim and Mark H. Tuszynski | Authors: Ritwik Vatsyayan, Fadi Khoury, Tara S Porter, Eleni Sinopoulou, Hadi Day, Samantha Russman, Rhea Montgomery-Walsh, Kaushik Shukla, Helen Saad, Andrew M Bourhis, Jihwan Lee, Karen J Tonsfeldt, Akira Nagamori, Hoi Sang U, David M Roth, Drew Hall, Sharona Ben-Haim, Eiman Azim, Tony L. Yaksh, Alexander […]


Continue.. Adaptive Charge Modulation Enables Focal, Selective Spinal Cord Stimulation

Ultralow frequency vaso-oscillations in human cerebral arteries are independent from Mayer waves

Kavli Affiliate: David Kleinfeld | Authors: Aiman Alzetani, Jacob Duckworth, Anthony A Birch, David M Simpson, David Kleinfeld and Roxana O Carare | Summary: This study tests the hypothesis that vasomotion, an ∼ 0.1 Hz oscillation in arteriole diameter, is generated by intrinsic oscillations within the arterioles that perfuse the brain, and not by external […]


Continue.. Ultralow frequency vaso-oscillations in human cerebral arteries are independent from Mayer waves

Functional brain organization is stable within individuals across years

Kavli Affiliate: Deanna J. Greene | Authors: Hyejin J. Lee, Ally Dworetsky, Alexis Porter, Sihan Fei, Ashley N. Nielsen, Benjamin A. Seitzman, Babatunde Adeyemo, Patrick G. Bissett, Russell A. Poldrack, Jessica R. Cohen, Mark D’Esposito, Maital Neta, Nico U.F. Dosenbach, Steven E. Petersen, Evan M. Gordon, Deanna J. Greene and Caterina Gratton | Summary: Brain […]


Continue.. Functional brain organization is stable within individuals across years

Multi-timescale learning signals in Drosophila dopaminergic neurons

Kavli Affiliate: Dhruv Grover | Authors: Woochan Choi, Shyam Srinivasan and Dhruv Grover | Summary: Learning often requires inference over hidden task structure, including features that predict outcomes. In mammals, prediction-error signaling by midbrain dopamine neurons is considered central to learning, but how these neurons reflect the progression and stability of learning remains unclear. Using […]


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Phasor EO-FLIM: Lifetime imaging with picosecond noise and 500 Hz frame rate

Kavli Affiliate: Kenta Asahina | Authors: Linghao Hu, Pingchuan Ma, Vaibhav Menon, Athira Sethu Madhavan, Kenta Asahina, Lena M. Müller and Adam J. Bowman | Summary: Fluorescence lifetime microscopy is limited by photon throughput, constraining the speed and dynamic range of biological measurements. We demonstrate a compact optical module and fast phasor acquisition methods to […]


Continue.. Phasor EO-FLIM: Lifetime imaging with picosecond noise and 500 Hz frame rate

High-resolution volumetric intravital imaging reveals asymmetric serotonin-dependent post-shock activity in the Drosophila brain

Kavli Affiliate: Ann-Shyn Chiang | Authors: Heng Chang, Yueh-Feng Wu, Ching-Che Charng, Kai-Chun Jhan, Shun-Chi Wu, Ann-Shyn Chiang, Hsiao-Chun Amy Lin, Chung-Chuan Lo, Bi-Chang Chen, Sung-Jan Lin and Li-An Chu | Summary: Volumetric intravital imaging of adult Drosophila brains remains challenging due to optical scattering and speed limitations of conventional microscopy. Here, we present V-shape […]


Continue.. High-resolution volumetric intravital imaging reveals asymmetric serotonin-dependent post-shock activity in the Drosophila brain

Extended-Interval Theta Burst Stimulation Enhances Glutamatergic Plasticity and Antidepressant Effects via Reduced GABAergic Recruitment

Kavli Affiliate: Dhakshin Ramanathan and Jyoti Mishra | Authors: Morteza Salimi, Milad Nazari, Anna Linnik, Shruti Joshi, Jonathan Mishler, Ryan Golden, Maxim Bazhenov, Jennifer Rodger, Sahar Jomehpour, Miranda Francoeur Koloski, Jyoti Mishra and Dhakshin Ramanathan | Summary: Intermittent Theta Burst Stimulation (iTBS) is a patterned stimulation protocol FDA-cleared to treat depression, yet its outcomes are […]


Continue.. Extended-Interval Theta Burst Stimulation Enhances Glutamatergic Plasticity and Antidepressant Effects via Reduced GABAergic Recruitment