Kavli Affiliate: Terrence Sejnowski | Authors: Margot Wagner, Yusi Chen, Arjun Karuvally, Mia Cameron and Terrence J Sejnowski | Summary: sequential dynamics underlying replay, prediction and traveling waves. How hippocampal circuitry achieves both remains unclear. Here, we show that recurrent neural networks trained on continuous prediction tasks converge to a mixed-symmetry dynamical regime, in which […]

Kavli Affiliate: Kenta Asahina | Authors: Lesly M Palacios Castillo, Valentina Fajner, Ezgi Yalbir, Shafana Shahul, Bruce Ruff, Victor Junmyung Lee, Aundrea Koger, Juliet Heller, Kenichi Ishii, Veronica Morad, Max Trask, Carter Warren, Giovanni Frighetto, Mark A Frye and Kenta Asahina | Summary: Octopamine (OA) is a major biogenic amine in the invertebrate nervous system […]

Kavli Affiliate: Cory Miller | Authors: Jingwen Li, Vikram Pal Singh, Jude F. Mitchell, Alexander C. Huk and Cory T. Miller | Summary: Human and nonhuman primates rely heavily on vision to actively explore and navigate their environment. Although primate visual cortex has been studied extensively in head-fixed animals, little is known about how the […]

Kavli Affiliate: Wesley Thompson | Authors: Michael Rosario, Carlos Cardenas-Iniguez, Jennifer V Chavez, Katherine L Bottenhorn, Hedyeh Ahmadi, Megan M Herting and Wesley K Thompson | Summary: Background Enriched environments support neurodevelopment. The pathways linking enrichment to cognitive processes such as episodic memory among youth remain unclear. This study examined whether brain function and structure […]

Kavli Affiliate: Sreekanth Chalasani | Authors: Lei Zhang, Jing Zhang, Tsui-Min Wang, Callum Walsh, Farah Sheikh, Sreekanth H. Chalasani and James Friend | Summary: Electronic cardiac pacemakers are the standard of care for treating arrhythmias but, even for wireless pacemakers, they require an intracardiac implant procedure and are invasive. Lead-related complications, including life-threatening infections, and […]

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Jill Leutgeb | Authors: Laura A. Ewell, Ario Ramezani, Gabrielle Suarez, Veronica C. Piatti, Vicky Lam, Tatyana G. Mills, Anelah McGinness, Raafat Kuk, Mika Ukai, Anna-Lena Schlenner, Stefan Leutgeb and Jill K. Leutgeb | Summary: The dentate gyrus of the […]

Kavli Affiliate: Timothy Brown | Authors: Nikunj Goel, Christen M. Bossu, Seorim Yi, Erica C. N. Robertson, Timothy M. Brown, Peri E. Bolton, Ben J. Vernasco, Erika Zavaleta, Kristen C. Ruegg and Mevin B. Hooten | Summary: Successful implementation of evolutionary management programs to rescue climatically threatened species requires identification of adaptive genetic variation. Although […]

Kavli Affiliate: Marcelo Mattar | Authors: Jonathan Nicholas and Marcelo G Mattar | Summary: Our experiences contain countless details that may be important in the future, yet we rarely know which will matter and which won’t. This uncertainty poses a difficult challenge for adaptive decision making, as failing to preserve relevant information can prevent us […]

Kavli Affiliate: Ann-Shyn Chiang | Authors: Chi-Lien Yang, Chia-Wen Chen, Kuan-Lin Feng, Hsiao-Chien Peng, Ming-Chin Wu, Ching-Che Charng, Li-An Chu, Yeong-Ray Wen and Ann-Shyn Chiang | Summary: In Drosophila, noxious heat is detected by peripheral nociceptors expressing transient receptor potential (TRP) channels, including Painless and TrpA1, and rapidly triggers escape behavior. Although peripheral transduction has […]

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Cory Miller | Authors: Arthur Lefevre, Vikram Pal Singh, Timothy Tyree, Jingwen Li, Jean-Rene Duhamel and Cory Miller | Summary: The Cocktail Party Problem (CPP) – extracting meaningful signals amid competing voices – remains poorly understood at the neural level, […]