Individualized network topography in pre-adolescent children and adults using naturalistic precision fMRI

Kavli Affiliate: Deanna J. Greene | Authors: Shefali Sanjana Rai, Kate J. Godfrey, Kirk Graff, Ryann Tansey, Daria Merrikh, Shelly Yin, Matthew Feigelis, Damion Demeter, Tamara Vanderwal, Deanna J. Greene and Signe L. Bray | Summary: Group-averaged network definitions, commonly used in developmental functional connectivity research, limit our understanding of how network topography may change […]


Continue.. Individualized network topography in pre-adolescent children and adults using naturalistic precision fMRI

Structural variants contribute substantially to complex trait heritability

Kavli Affiliate: Anders Dale | Authors: Dat Thanh Nguyen, Alexey A Shadrin, Nadine Parker, Julian Fuhrer, Nam Sy Vo, Anders Dale, Ole Andreassen and Oleksandr Frei | Summary: Despite accumulating evidence that structural variants (SVs) exert disproportionate functional effects, their genome-wide contribution to complex trait heritability has not yet been systematically quantified. Here, we introduce […]


Continue.. Structural variants contribute substantially to complex trait heritability

Synaptic Spine Head Morphodynamics from Graph Grammar Rules for Actin Dynamics

Kavli Affiliate: Terrence Sejnowski | Authors: Matthew Hur, Thomas Bartol, Padmini Rangamani, Terrence Sejnowski and Eric Mjolsness | Summary: There is a morphodynamic component to synaptic learning by which changes in dendritic (postsynaptic) spine head size are associated with the strengthening or weakening of the synaptic connection between two neurons, in response to the temporal […]


Continue.. Synaptic Spine Head Morphodynamics from Graph Grammar Rules for Actin Dynamics

A generalized synthetic control algorithm for sparse functional data

Kavli Affiliate: Wesley Thompson | Authors: Lucy Shao, Kilian M. Pohl and Wesley K. Thompson | Summary: The Synthetic Control Method (SCM) and its interactive factor model generalizations (GSC) are powerful for estimating causal effects from panel data but are not easily applied when follow-up is irregular or sparse, common features of biomedical cohorts. We […]


Continue.. A generalized synthetic control algorithm for sparse functional data

Cortical oscillations reflect opponent ensemble dynamics through coordinated multifrequency activity

Kavli Affiliate: Dhakshin Ramanathan and Jyoti Mishra | Authors: Jonathan H Mishler, Morteza Salimi, Miranda Francoeur Koloski, Irene Rembado, Carrie Shilyansky, Jyoti Mishra and Dhakshin Ramanathan | Summary: Neural oscillations are widely used as proxies for neuronal activity, where power in individual frequency bands is commonly interpreted as functionally indexing neural circuit engagement. However, power […]


Continue.. Cortical oscillations reflect opponent ensemble dynamics through coordinated multifrequency activity

Neural circuits regulating social dominance implement a strategy predicted by evolutionary game theory

Kavli Affiliate: Kenta Asahina | Authors: Donovan Ventimiglia, Elizabeth Chamiec-Case, Claire S Lee, Bruce Ruff and Kenta Asahina | Summary: Social conflict is a fundamental challenge for all animals and determines access to critical resources like mates and food. Evolutionary game theory predicts that natural selection should yield competitive strategies that balance the benefits and […]


Continue.. Neural circuits regulating social dominance implement a strategy predicted by evolutionary game theory

Latent-centric Isotropic Resolution Enhancement for Expansion Microscopy Imaging via Neural Compression and Self-supervised Learning

Kavli Affiliate: Ann-Shyn Chiang | Authors: Pin-Hsun Lian, Tzu-Yi Chuang, Ya-Ding Liu, Li-An Chu, Sheng-Cheng Chang, Yu-Chen Kuo, Wei-Kun Chang, Ann-Shyn Chiang and Gary Chang | Summary: Expansion microscopy (ExM) enables nanoscale imaging for disease characterization. However, whole-organ analyses remain limited by several challenges. Current super-resolution methods either require high-resolution ground-truth data or assume spatially […]


Continue.. Latent-centric Isotropic Resolution Enhancement for Expansion Microscopy Imaging via Neural Compression and Self-supervised Learning

Balancing Stability and Flow in Hippocampal Networks via Inductive Bias and Learned Symmetry Breaking

Kavli Affiliate: Terrence Sejnowski | Authors: Margot Wagner, Yusi Chen, Arjun Karuvally, Mia Cameron and Terrence J Sejnowski | Summary: sequential dynamics underlying replay, prediction and traveling waves. How hippocampal circuitry achieves both remains unclear. Here, we show that recurrent neural networks trained on continuous prediction tasks converge to a mixed-symmetry dynamical regime, in which […]


Continue.. Balancing Stability and Flow in Hippocampal Networks via Inductive Bias and Learned Symmetry Breaking

Cellular and functional dissection of the octopaminergic system in the Drosophila brain

Kavli Affiliate: Kenta Asahina | Authors: Lesly M Palacios Castillo, Valentina Fajner, Ezgi Yalbir, Shafana Shahul, Bruce Ruff, Victor Junmyung Lee, Aundrea Koger, Juliet Heller, Kenichi Ishii, Veronica Morad, Max Trask, Carter Warren, Giovanni Frighetto, Mark A Frye and Kenta Asahina | Summary: Octopamine (OA) is a major biogenic amine in the invertebrate nervous system […]


Continue.. Cellular and functional dissection of the octopaminergic system in the Drosophila brain

Active gaze behavior organizes V1 activity in freely-moving marmosets

Kavli Affiliate: Cory Miller | Authors: Jingwen Li, Vikram Pal Singh, Jude F. Mitchell, Alexander C. Huk and Cory T. Miller | Summary: Human and nonhuman primates rely heavily on vision to actively explore and navigate their environment. Although primate visual cortex has been studied extensively in head-fixed animals, little is known about how the […]


Continue.. Active gaze behavior organizes V1 activity in freely-moving marmosets