Olfactory neuronal cells: biopsied surrogates for neurons in the brain

Kavli Affiliate: Donald Geman, Laurent Younes | Authors: Kun Yang, Koko Ishizuka, Zui Narita, Yukiko Y Lema, Siwei Zhang, Jubao Duan, Laurent Younes, Donald Geman, Andrew P Lane and Akira Sawa | Summary: ABSTRACT Biopsy is an essential procedure of clinical medicine in which we obtain tissues and cells that are supposed to directly reflect […]


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Temporal dynamics of the multi-omic response to endurance exercise training across tissues

Kavli Affiliate: Michael Miller | Authors: MoTrPAC Study Group, David Amar, Nicole R. Gay, Pierre M. Jean Beltran, Joshua N. Adkins, Jose J. Almagro Armenteros, Euan Ashley, Julian Avila-Pacheco, Dam Bae, Nasim Bararpour, Charles Burant, Clary Clish, Gary Cutter, Surendra Dasari, Courtney Dennis, Charles R. Evans, Facundo M. Fernández, David Gaul, Yongchao Ge, Robert Gerszten, […]


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Visuospatial information foraging describes search behavior in learning latent environmental features

Kavli Affiliate: C. Daniel Salzman | Authors: David L Barack, Akram Bakkour, Daphna Shohamy and C Daniel Salzman | Summary: Abstract In the real world, making sequences of decisions to achieve goals often depends upon the ability to learn aspects of the environment that are not directly perceptible. Learning these so-called latent features requires seeking […]


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Corticothalamic Neurons in Motor Cortex Have a Permissive Role in Motor Execution

Kavli Affiliate: Costa, Rui | Authors: Lina Marcela Carmona, Lin T Tun, An Kim, Rani Shiao, Michael D Kissner, Vilas Menon and Rui M Costa | Summary: ABSTRACT The primary motor cortex (M1) is a central hub for motor learning and execution, as it receives input from and broadcasts to a multitude of other motor […]


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Dynamic refinement of behavioral structure mediates dopamine-dependent credit assignment

Kavli Affiliate: Costa, Rui | Authors: Jonathan C.Y. Tang, Vitor Paixao, Filipe Carvalho, Artur Silva, Andreas Klaus, Joaquim Alves da Silva and Rui M Costa | Summary: Abstract Animals exhibit a diverse behavioral repertoire when exploring new environments and can learn which actions or action sequences produce positive outcomes. Dopamine release upon encountering reward is […]


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Microbiota-stimulated Interleukin-22 regulates brain neurons and protects against stress-induced anxiety

Kavli Affiliate: Jeffrey Friedman | Authors: Anoj Ilanges, Mengyu Xia, Junmei Lu, Lei Chen, Rani Shiao, Changchun Wang, Ru Feng, Zheyu Jin, Han Yi, Qingqing Qi, Jixi Li, Marc Schneeberger, Boxun Lu, Jeffrey M. Friedman and Xiaofei Yu | Summary: Summary Psychological stress and its sequelae are a major public health problem. While the immune […]


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Historical biogeography of Cannabis in the Iberian Peninsula: palynological evidence

Kavli Affiliate: Jose Suarez Lopez | Authors: Valenti Rull, Francesc Burjachs, Jose Carrion, Ana Ejarque, Santiago Fernandez, Jose Antonio Lopez-Saez, Reyes Luelmo-Lautenschlaeger, Juan Ochando, Sebastian Perez-Diaz, Jordi Revelles, Santiago Riera and Sara Rodriguez | Summary: Abstract The tempo and mode of colonization of the Iberian Peninsula (IP) by Cannabis sativa, its further internal spreading and […]


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Neuromodulatory silencing of nerve terminals

Kavli Affiliate: Timothy A. Ryan | Authors: Daniel Charles Cook and Timothy Aidan Ryan | Summary: Abstract Control of neurotransmission efficacy is central to theories of how the brain computes and stores information. Neuromodulators are critical in this problem as they locally influence synaptic strength and can operate on a wide range of time scales. […]


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Cortico-cortical and hippocampo-cortical co-rippling are facilitated by thalamo-cortical spindles and upstates, but not by thalamic ripples

Kavli Affiliate: Eric Halgren | Authors: Charles W Dickey, Ilya A Verzhbinsky, Sophie Kajfez, Burke Q Rosen, Sandipan Pati and Eric Halgren | Summary: Abstract The co-occurrence of brief ~90 Hz oscillations (co-ripples) may be important in integrating information across the cortex and hippocampus, essential for sleep consolidation, and cognition in general. However, how such […]


Continue.. Cortico-cortical and hippocampo-cortical co-rippling are facilitated by thalamo-cortical spindles and upstates, but not by thalamic ripples

Multi-areal neural dynamics encode human decision making

Kavli Affiliate: Edward Chang | Authors: Jacqueline A Overton, Karen A Moxon, Matthew P Stickle, Logan M Peters, Jack J Lin, Edward F Chang, Robert T Knight, Ming Hsu and Ignacio Saez | Summary: Abstract Value-based decision-making involves multiple cortical and subcortical brain areas, but the exact nature of neural activity underlying choice behavior has […]


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