Neuroscience – Page 98 – Kavli Institute Pre-Print Publications

A germline-targeting chimpanzee SIV envelope glycoprotein elicits a new class of V2-apex directed cross-neutralizing antibodies

Posted by klaurent October 21, 2022November 1, 2022UCSF

Kavli Affiliate: Robert Edwards | Authors: Frederic Bibollet-Ruche, Ronnie M Russell, Wenge Ding, Weimin Liu, Yingying Li, Kshitij Wagh, Daniel Wrapp, Rumi Habib, Ashwin N Skelly, Ryan S Roark, Scott Sherrill-Mix, Shuyi Wang, Juliette Rando, Emily Lindemuth, Kendra Cruickshank, Younghoon Park, Rachel Baum, Andrew Connell, Hui Li, Elena E Giorgi, Ge S Song, Shilei Ding, […]

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Microscopic Imaging of Epigenetic Age

Posted by klaurent October 20, 2022November 1, 2022UCSD / Salk

Kavli Affiliate: Tatyana Sharpee | Authors: Delany Rodriguez, Lorenzo Fiengo, Martin Alvarez-Kuglen, Haodong Qin, Chen Farhy, Aaron Havas, Rozalyn M Anderson, Peter D Adams, Tatyana O Sharpee and Alexey Terskikh | Summary: ABSTRACT Predictive biomarkers of functional or biological age are key for evaluating interventions aimed at increasing healthspan and / or lifespan in humans. […]

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A tissue injury repair pathway distinct but parallel to host pathogen defense

Posted by klaurent October 19, 2022November 1, 2022Rockefeller

Kavli Affiliate: Daniel S. Mucida, Elaine Fuchs | Authors: Siqi Liu, Yun Ha Hur, Xin Cai, Qian Cong, Yihao Yang, Chiwei Xu, Angelina M Bilate, Kevin Andrew Uy Gonzales, Christopher J. Cowley, Brian Hurwitz, Ji-Dung Luo, Tiffany Tseng, Shiri Gur-Cohen, Megan Sribour, Tatiana Omelchenko, John Levorse, H Amalia Pasolli, Criag B Thompson, Daniel Mucida and […]

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MLL1 regulates cytokine-driven cell migration and metastasis

Posted by klaurent October 19, 2022November 1, 2022Hopkins

Kavli Affiliate: Denis Wirtz | Authors: Praful R Nair, Ludmila Danilova, Estibaliz Gómez-de-Mariscal, Dongjoo Kim, Rong Fan, Arrate Munoz-Barrutia, Elana J Fertig and Denis Wirtz | Summary: Abstract Cell migration is a critical requirement for cancer metastasis. Cytokine production and its role in cancer cell migration have been traditionally associated with immune cells in the […]

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Autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes

Posted by klaurent October 18, 2022November 28, 2022UCSF

Kavli Affiliate: John Rubenstein | Authors: Siavash Fazel Darbandi, Joon-Yong An, Kenneth Lim, Nicholas F. Page, Lindsay Liang, Athena R. Ypsilanti, Eirene Markenscoff-Papadimitriou, Matthew W. State, Alex S. Nord, Stephan J. Sanders and John L. R. Rubenstein | Summary: Abstract The authors have withdrawn their manuscript because of uncertainty about an antibody reagent that was […]

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Internal noise promotes heterogeneous synaptic dynamics important for working memory in recurrent neural networks

Posted by klaurent October 18, 2022November 1, 2022UCSD / Salk

Kavli Affiliate: Terrence Sejnowski | Authors: Nuttida Rungratsameetaweemana, Robert Kim and Terrence Sejnowski | Summary: Abstract Recurrent neural networks (RNNs) based on model neurons that communicate via continuous signals have been widely used to study how cortical neurons perform cognitive tasks. Training such networks to perform tasks that require information maintenance over a brief period […]

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DNA Methylation Signatures in Breast Cancer: A Systematic Review and Meta-Analysis

Posted by klaurent October 18, 2022November 1, 2022UCSD / Salk

Kavli Affiliate: Terrence Sejnowski | Authors: Antonio Pinto-Duarte, Katherine Bogue, Terrence J Sejnowski and Shyam Srinivasan | Summary: Abstract Epigenetic changes are involved in the onset and progression of cancer, and the detection of DNA methylation signatures may foster the improvement of diagnosis and prognosis. While the emergence of innovative technologies has fostered numerous studies […]

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Molecular programs of regional specification and neural stem cell fate progression in developing macaque telencephalon

Posted by klaurent October 18, 2022November 14, 2022Yale

Kavli Affiliate: Pasko Rakic, Nenad Sestan | Authors: Nicola Micali, Shaojie Ma, Mingfeng Li, Suel-Kee Kim, Xoel Mato-Blanco, Suvimal Sindhu, Jon I. Arellano, Tianliuyun Gao, Alvaro Duque, Gabriel Santpere, Nenad Sestan and Pasko Rakic | Summary: Abstract Early telencephalic development involves patterning of the distinct regions and fate specification of the neural stem cells (NSCs). […]

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Knowledge Mapping of Alternative Splicing of Cancer From 2012 to 2021: A Bibliometric Analysis

Posted by klaurent October 17, 2022November 1, 2022Rockefeller

Kavli Affiliate: Li Zhao | Authors: Bo Tian, Yan Bian, De-Jian Bian, Ye Gao, Xun Zhang, Si-Wei Zhou, Yan-Hui Zhang, Ya-Nan Pang, Zhao-Shen Li and Luo-Wei Wang | Summary: ABSTRACT Background As a processing method of RNA precursors, alternative splicing plays a critical role in normal cell physiological activities. Aberrant alternative splicing events are associated […]

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A machine learning based approach towards high-dimensional mediation analysis

Posted by klaurent October 11, 2022October 24, 2022Hopkins

Kavli Affiliate: Brian Caffo, Martin Lindquist | Authors: Tanmay Nath, Brian Caffo, Tor Wager and Martin Lindquist | Summary: Abstract Mediation analysis is used to investigate the role of intermediate variables (mediators) that lie in the path between an exposure and an outcome variable. While significant research has focused on developing methods for assessing the […]

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