Kavli Affiliate: Eric Halgren | Authors:Charles W Dickey, Ilya A Verzhbinsky, Xi Jiang, Burke Q Rosen, Sophie Kajfez, Emad N Eskandar, Jorge Gonzalez-Martinez, Sydney S Cash and Eric Halgren | Summary: Hippocampal ripples index the reconstruction of spatiotemporal neuronal firing patterns essential for the consolidation of memories in the cortex during non-rapid eye movement sleep […]
Kavli Affiliate: Sreekanth Chalasani, Ethan Bier | Authors: Anupama Singh, Bhagyashree Kaduskar, Kirthi C Reddy, Caroline Kumsta, Ethan Bier, Malene Hansen and Sreekanth H Chalasani | Summary: Age-related decline in intestinal barrier function impacts survival across species, but the underlying cell intrinsic and extrinsic factors remain unclear. Here, we demonstrate a role for neuropeptides in […]
Kavli Affiliate: Fred Gage, Terrence Sejnowski | Authors: Thodoros Bermperidis, Simon Schafer, Fred H. Gage, Terrence Sejnowski and Elizabeth B Torres | Summary: The advent of open access to genomic data offers new opportunities to revisit old clinical debates while approaching them from a different angle. We examine anew the question of whether psychiatric and […]
Kavli Affiliate: Eric Halgren | Authors: Charles W Dickey, Ilya A Verzhbinsky, Xi Jiang, Burke Q Rosen, Sophie Kajfez, Brittany Stedelin, Jerry J Shih, Sharona Ben-Haim, Ahmed M Raslan, Emad N Eskandar, Jorge Gonzalez-Martinez, Sydney S Cash and Eric Halgren | Summary: Declarative memory encoding, consolidation, and retrieval require the integration of elements encoded in […]
Kavli Affiliate: Michael Nitabach | Authors: Evripidis Gkanias, Li Yan McCurdy, Michael N Nitabach and Barbara Webb | Summary: Insects adapt their response to stimuli, such as odours, according to their pairing with positive or negative reinforcements, such as sugar or shock. Recent electrophysiological and imaging findings in Drosophila melanogaster allow detailed examination of the […]
Kavli Affiliate: Loren Frank | Authors: Abhilasha Joshi, Eric L. Denovellis, Abhijith Mankili, Yagiz Meneksedag, Thomas Davidson, Anna K Gillespie, Jennifer Ann Guidera, Demetris Roumis and Loren M. Frank | Summary: The hippocampus is a vertebrate brain structure that expresses spatial representations1 and is critical for navigation2,3. Navigation in turn intricately depends on locomotion; however, […]
Kavli Affiliate: Sridevi Sarma | Authors: Adam G Rouse, Marc H Schieber and Sridevi V Sarma | Summary: Reaching movements are known to have large condition-independent neural activity and cyclic neural dynamics. A new precision center-out task was performed by rhesus macaques to test the hypothesis that cyclic, condition-independent neural activity in the primary motor […]
Kavli Affiliate: Henry Abarbanel | Authors: Randall E Clark, Lawson Fuller, Jason A Platt and Henry Abarbanel | Summary: Using methods from nonlinear dynamics and interpolation techniques from applied mathematics, we show how to use data alone to construct discrete time dynamical rules that forecast observed neuron properties. These data may come from from simulations […]
Kavli Affiliate: Stefano Fusi | Authors: Li Ji-An, Fabio Stefanini, Marcus K Benna and Stefano Fusi | Summary: Synaptic plasticity is a complex phenomenon involving multiple biochemical processes that operate on different timescales. We recently showed that this complexity can greatly increase the memory capacity of neural networks when the variables that characterize the synaptic […]
Kavli Affiliate: Anastasia Kiyonaga | Authors: Jacob Miller, Arielle Tambini, Anastasia Kiyonaga and Mark D’Esposito | Summary: The lateral prefrontal cortex (lPFC) is reliably active during working memory (WM) across human and animal models, but the role of lPFC in successful WM is under debate. For instance, non-human primate (NHP) electrophysiology research finds that lPFC […]