Kavli Affiliate: Roger Nicoll | Authors: XIUMIN CHEN, Qixu Cai, jing zhou, Samuel J Pleasure, Howard Schulman, Mingjie Zhang and Roger A Nicoll | Summary: CaMKII plays a critical role in long-term potentiation (LTP), a well-established model for learning and memory through the enhancement of synaptic transmission. Biochemical studies indicate that CaMKII catalyzes a phosphotransferase […]
Continue.. CaMKII autophosphorylation but not downstream kinase activity is required for synaptic memory