The value of initiating a pursuit in temporal decision-making

Kavli Affiliate: Marshall Hussain Shuler | Authors: Elissa Sutlief, Charlie Walters, Tanya Marton and Marshall G Hussain Shuler | Summary: Reward rate maximization is a prominent normative principle commonly held in behavioral ecology, neuroscience, economics, and artificial intelligence. Here, we identify and compare equations for evaluating the worth of initiating pursuits that an agent could […]


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Network nature of ligand-receptor interactions underlies disease comorbidity in the brain

Kavli Affiliate: Keri Martinowich | Authors: Melissa Grant-Peters, Aine Fairbrother-Browne, Amy Hicks, Boyi Guo, Regina H. Reynolds, Louise A. Huuki-Myers, Nick Eagles, Jonathan Brenton, Sonia Garcia-Ruiz, Nicholas Wood, Sonia Gandhi, Keri Martinowich, Kristen Maynard, Leonardo Collado-Torres and Mina Ryten | Summary: Neurodegenerative disorders have overlapping symptoms and have high comorbidity rates, but this is not […]


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Early Developmental Origins of Cortical Disorders Modeled in Human Neural Stem Cells

Kavli Affiliate: Flora Vaccarino | Authors: Xoel Mato-Blanco, Suel-Kee Kim, Alexandre Jourdon, Shaojie Ma, Andrew T.N. Tebbenkamp, Fuchen Liu, Alvaro Duque, Flora M. Vaccarino, Nenad Sestan, Carlo Colantuoni, Pasko Rakic, Gabriel Santpere and Nicola Micali | Summary: The implications of the early phases of human telencephalic development, involving neural stem cells (NSCs), in the etiology […]


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Missing data approaches for longitudinal neuroimaging research: Examples from the Adolescent Brain and Cognitive Development (ABCD) Study

Kavli Affiliate: Wesley Thompson | Authors: Lin Li, Mohammadreza Bayat, Timothy Hayes, Wesley K. Thompson, Arianna Morgan Sandmark Gard and Anthony Steven Dick | Summary: This paper addresses the challenges of managing missing values within expansive longitudinal neuroimaging datasets, using the specific example of data derived from the Adolescent Brain and Cognitive Development ABCD study. […]


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Variable recruitment of distal tuft dendrites shapes new hippocampal place fields

Kavli Affiliate: Attila Losonczy and Franck Polleux | Authors: Justin K. O’Hare, Jamie Wang, Margjele D. Shala, Franck Polleux and Attila Losonczy | Summary: Hippocampal pyramidal neurons support episodic memory by integrating complementary information streams into new ‘place fields’. Distal tuft dendrites are widely thought to initiate place field formation by locally generating prolonged, globally-spreading […]


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A feedforward mechanism for human-like contour integration

Kavli Affiliate: George A. Alvarez | Authors: Nathan Wu, Baohua Zhou, Margarida Agrochao and Damon A Clark | Summary: Our intuition suggests that when a movie is played in reverse, our perception of motion in the reversed movie will be perfectly inverted compared to the original. This intuition is also reflected in many classical theoretical […]


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Functional connectome through the human life span

Kavli Affiliate: Xiaoqin Wang | Authors: Lianglong Sun, Tengda Zhao, Xinyuan Liang, Mingrui Xia, Qiongling Li, Xuhong Liao, Gaolang Gong, Qian Wang, Chenxuan Pang, Qian Yu, Yanchao Bi, Pindong Chen, Rui Chen, Yuan Chen, Taolin Chen, Jingliang Cheng, Yuqi Cheng, Zaixu Cui, Zhengjia Dai, Yao Deng, Yuyin Ding, Qi Dong, Dingna Duan, Jia-Hong Gao, Qiyong […]


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Broken time reversal symmetry in visual motion detection

Kavli Affiliate: Damon Clark | Authors: Nathan Wu, Baohua Zhou, Margarida Agrochao and Damon A Clark | Summary: Our intuition suggests that when a movie is played in reverse, our perception of motion in the reversed movie will be perfectly inverted compared to the original. This intuition is also reflected in many classical theoretical and […]


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Spatial Single-cell Analysis Decodes Cortical Layer and Area Specification

Kavli Affiliate: Michael Miller | Authors: Xuyu Qian, Kyle Coleman, Shunzhou Jiang, Andrea J Kriz, Jack H Marciano, Chunyu Luo, Chunhui Cai, Monica D Manam, Emre Caglayan, Aoi Otani, Urmi Ghosh, Diane D Shao, Rebecca E Andersen, Jennifer E Neil, Robert Johnson, Alexandra LeFevre, Jonathan L Hecht, Michael B Miller, Liang Sun, Carsen Stringer, Mingyao […]


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Hypothalamic CRH Neurons Modulate Sevoflurane Anesthesia and The Post-anesthesia Stress Responses

Kavli Affiliate: Wei Min | Authors: Shan Jiang, Lu Chen, Wei-Min Qu, Zhi-Li Huang and Chang-Rui Chen | Summary: General anesthesia is a fundamental process required to undertake safely and humanely a high fraction of surgeries and invasive diagnostic procedures. However, the undesired stress response associated with general anesthesia (GA) causes delayed recovery and even […]


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