Kavli Affiliate: Loren Frank | Authors: Anna K Gillespie, Daniela A Astudillo Maya, Eric L. Denovellis, Sachi Desse and Loren M Frank | Summary: Hippocampal replay – the time-compressed, sequential reactivation of ensembles of neurons related to past experience – is a key neural mechanism of memory consolidation. Replay typically coincides with a characteristic pattern […]
Kavli Affiliate: Jeremy Willsey | Authors: Belinda Wang, Rasika Vartak, Yefim Zaltsman, Zun Zar Chi Naing, Kelsey M Hennick, Benjamin J Polacco, Ali Bashir, Manon Eckhardt, Mehdi Bouhaddou, Jiewei Xu, Nawei Sun, Micaela Lasser, Yuan Zhou, Keelan Z Guiley, Una Chan, Julia A Kaye, Prachi Khare, Sam Drake, Vanessa Drury, David F Burke, Silvano Gonzalez, […]
Kavli Affiliate: Yifan Cheng | Authors: He Chen, Yifan Cheng, Jianqiang Dong, Jie Mao, Xin Wang, Yuan Gao, Yuchao Li, Chengzhi Wang and Qiong Wu | Summary: Predicting the properties of proteins is an important procedure in protein engineering. It determines the subspace of mutations for protein modifications, which is critical to the success of […]
Kavli Affiliate: Erich Jarvis | Authors: Jun Ishigohoka, Karen Bascón-Cardozo, Andrea Bours, Janina Fuß, Arang Rhie, Jacquelyn Mountcastle, Bettina Haase, William Chow, Joanna Collins, Kerstin Howe, Marcela Uliano-Silva, Olivier Fedrigo, Erich D. Jarvis, Javier Pérez-Tris, Juan Carlos Illera and Miriam Liedvogel | Summary: Genetic variation of the entire genome represents population structure, yet individual loci […]
Kavli Affiliate: Terrence Sejnowski | Authors: Yusi Chen, Huanqiu Zhang, Mia Cameron and Terrence J Sejnowski | Summary: The hippocampus receives sequences of sensory inputs from the cortex during exploration and encodes the sequences with millisecond precision. We developed a predictive autoencoder model of the hippocampus including the trisynaptic and monosynaptic circuits from the entorhinal […]
Kavli Affiliate: Denis Wirtz | Authors: Bartholomew Starich, Fan Yang, Derin Tanrioven, Heng-Chung Kung, Joanne Baek, Praful R. Nair, Pratik Kamat, Nico Macaluso, Joon Eoh, Kyu Sang Han, Luo Gu, Sean Sun, Pei-Hsun Wu, Denis Wirtz and Jude M. Phillip | Summary: Cellular senescence is a major driver of aging and disease. Here we show […]
Kavli Affiliate: Anirvan Nandy | Authors: Anirban Das, Alec G. Sheffield, Anirvan S. Nandy and Monika P. Jadi | Summary: Adaptive information processing, comprised of local computations and their efficient routing, is crucial for flexible brain function. Spatial attention is a quintessential example of this adaptive process. It is critical for recognizing and interacting with […]
Kavli Affiliate: Erich Jarvis | Authors: Elena N Waidmann, Victor HY Yang, William C Doyle and Erich D Jarvis | Summary: Vocal communication is a major component of animal social behavior. Vocalizations can be learned or innate, and can convey a variety of signals, including territorial limits, the presence of predators, or courtship intent. Mouse […]
Kavli Affiliate: Erich Jarvis | Authors: César D M Vargas, Rajvi K Agravat, Elena N Waidmann, Christodoulos Bochalis, Hector Bermudez, Theodoros Giannakopoulos and Erich D Jarvis | Summary: Vocalization is a complex behavior ranging from fully innate to advanced vocal learning. Vocal learning species possess a vocal primary motor cortex (M1) region that makes direct […]
Kavli Affiliate: Liam Paninski Mark Churchland | Authors: Andrew J Zimnik, K. Cora Ames, Xinyue An, Laura Driscoll, Antonio H Lara, Abigail A Russo, Vladislav Susoy, John P Cunningham, Liam Paninski, Mark M Churchland and Joshua I Glaser | Summary: In many neural populations, the computationally relevant signals are posited to be a set of […]