Kavli Affiliate: Arnold R. Kriegstein | Authors: Chujing Zhang, Eugene Gil, Sajad Hamid Ahanger, Mingcong Li, Li Wang, Eric J. Huang, Jingjing Li, Arnold R. Kriegstein and Daniel A. Lim | Summary: Approximately 30-40% of the human genome is anchored to the nuclear lamina (NL) through variably sized (10 kb-10 Mb) lamina-associated domains (LADs), which […]
Kavli Affiliate: Patricia Janak | Authors: Eric Garr, Yifeng Cheng, Andy Dong and Patricia H. Janak | Summary: It is commonly thought that drug addiction involves a transition to habitual control of action, where the choice to consume drugs becomes automatized and reflects a failure to deliberate over possible negative outcomes. Determining whether the pursuit […]
Kavli Affiliate: Vikaas Sohal | Authors: Cesar P Canales, Stephanie Lozano, Nicholas A Frost, Karol Cichewicz, Wellington Amaral, Nicolas Seban, Ethan Fenton, Ayanna Wade, Nickolas Chu, Emily Smith, Cory Ardekani, Samuel Frank, Jeffrey Bennett, Pierre Lavenex, Aspen Kopley-Smith, Darlene Rahbarian, Melisa Corea, Daniela Perla, Liam Davis, Jiyuan Zhu, Rebecca Ortiz, Paris Beauregard, Caitlin Moyer, Jacob […]
Kavli Affiliate: Martin Lindquist | Authors: Zizhuang Miao, Heejung Jung, Philip A. Kragel, Ke Bo, Patrick Sadil, Martin A. Lindquist and Tor D. Wager | Summary: Social interaction perception and theory of mind (ToM) frequently co-occur, but their commonalities and distinctions at behavioral and neural levels remain unclear. Participants (N = 231) provided moment-by-moment ratings […]
Kavli Affiliate: Attila Losonczy | Authors: Simone Tasciotti, Daniel Maxim Iascone, Spyridon Chavlis, Luke Hammond, Yardena Katz, Attila Losonczy, Franck Polleaux and Panayiota Poirazi | Summary: The synaptic mechanisms driving feature selectivity in specific neuron types remains a fundamental and unresolved challenge in neuroscience. In hippocampal CA1 pyramidal neurons (PNs), the development of place selectivity, […]
Kavli Affiliate: Patrick Kanold | Authors: HiJee Kang, Travis Babola and Patrick O Kanold | Summary: Sensory information is represented by small neuronal ensembles in sensory cortices. Neuronal activity shows high trial-by-trial variability in that repeated presentation of the same stimulus, e. g., multiple presentations of the same sound activate differing ensembles in the auditory […]
Kavli Affiliate: Marcelo Mattar | Authors: Hua-Dong Xiong, Li Ji-An, Marcelo G Mattar and Robert C Wilson | Summary: Cognitive modeling provides a formal method to articulate and test hypotheses about cognitive processes. However, accurately and reliably estimating model parameters remains challenging due to common issues in behavioral science, such as limited data, measurement noise, […]
Kavli Affiliate: Maryam Ziaei | Authors: Arjun Dave, Shuer Ye, Leona R Batz, Xiaqing Lan, Heidi Jacobs and Maryam Ziaei | Summary: Interpreting ambiguous environmental cues, like facial expressions, becomes increasingly challenging with age, especially as cognitive resources decline. Managing these challenges requires adaptive neural mechanisms that are essential for maintaining mental well-being. The locus […]
Kavli Affiliate: Michael J Higley | Authors: Saroj Sah, Andrew D Sauerbeck, Jyoti Gupta, Dayana Pérez-Acuña, Jacob E Reiber, Dreson Russell, Thomas Goralski, Michael Henderson, Laura A Volpicelli-Daley, Michael J Higley, Terrance T Kummer and Thomas Biederer | Summary: Cognitive impairment is a frequent non-motor symptom in Parkinson’s disease, and cortical Lewy pathology is strongly […]
Kavli Affiliate: Michael Miller | Authors: Bowen Jin, Katherine S.-M. Brown, Denis S. Smirnov, Samuel M. Naik, Samantha L. Kirkham, Elizabeth L. Hennessey, Guanlan Dong, Shulin Mao, Samadhi P. Wijethunga, Theresa Connors Stewart, Dennis J. Selkoe, Matthew P. Frosh, Derek H. Oakley, Bradley T. Hyman, August Yue Huang and Michael Miller | Summary: Tau deposition […]