Kavli Affiliate: Michael Keiser | Authors: Sina Ghandian, Liane Albarghouthi, Kiana Nava, Shivam R. Rai Sharma, Lise Minaud, Laurel Beckett, Naomi Saito, Charles DeCarli, Robert A. Rissman, Andrew F. Teich, Lee-Way Jin, Brittany N. Dugger and Michael J. Keiser | Summary: Accumulation of abnormal tau protein into neurofibrillary tangles (NFTs) is a pathologic hallmark of […]
Kavli Affiliate: Jose Ricardo Suarez | Authors: Pablo Carrion, Inigo Olalde, Juan Manuel Jimenez-Arenas, Neus Coromina, David Vivo, Josep Maria Verges, Ana Costa, Daniel Botella, Macarena Bustamante-Alvarez, Javier Heras-Mora, Ricardo Ortega-Ruiz, Celia Chaves, Maite Iris Garcia-Collado, Juan Quiros-Castillo, Jordi Roig, Jose Suarez-Padilla, Ildelfonso Navarro-Luengo, Miguel Angel Cuadrado, Isidro Aguilera, Jordi Morera, Raul Catalan, Maria Luisa […]
Kavli Affiliate: George A. Alvarez | Authors: Fenil R. Doshi, Talia Konkle and George A. Alvarez | Summary: Summary: Deep neural network models provide a powerful experimental platform for exploring core mechanisms underlying human visual perception, such as perceptual grouping and contour integration — the process of linking local edge elements to arrive at a […]
Kavli Affiliate: Michael Miller | Authors: Juthi Biswas, Dilruba Akter, Michael J Miller, Dennis J Thiele, Eain A. Murphy, Christine O’Connor, Jennifer F Moffat and Gary Chan | Summary: Summary: FDA-approved antivirals against HCMV have several limitations, including only targeting the later stages of the viral replication cycle, adverse side effects, and the emergence of […]
Kavli Affiliate: Joshua Berke and Loren Frank | Authors: Alison E. Comrie, Emily J. Monroe, Ari E. Kahn, Eric L. Denovellis, Abhilasha Joshi, Jennifer A. Guidera, Timothy A. Krausz, Joshua D. Berke, Nathaniel D. Daw and Loren M. Frank | Summary: Summary: The cognitive ability to go beyond the present to consider alternative possibilities, including […]
Kavli Affiliate: Edward Callaway | Authors: Li Alex Zhang, Peichao Li and Edward M. Callaway | Summary: Summary: Laminar electrode arrays allow simultaneous recording of activity of many cortical neurons and assignment to layers using current source density (CSD) analyses. Electrode arrays with 100-micron contact spacing have been used to estimate borders between layer 4 […]
Kavli Affiliate: Keri Martinowich | Authors: Amber M Smith, Yang Li, Arianna Velarde, Yifan Cheng and Alan D. Frankel | Summary: Summary: Crm1 is a highly conserved nuclear exportin that transports >1000 human proteins including ribonucleoprotein (RNP) complexes. The interface between Crm1 and RNP cargos is unknown. The HIV regulatory protein, Rev, was one of […]
Kavli Affiliate: Keri Martinowich | Authors: Robert A Phillips III, Seyun Oh, Svitlana V Bach, Yufeng Du, Ryan A Miller, Joel E Kleinman, Thomas M Hyde, Stephanie C Hicks, Stephanie Cerceo Page and Keri Martinowich | Summary: The lateral septum (LS) is a midline, subcortical structure, which regulates social behaviors that are frequently impaired in […]
Kavli Affiliate: Andreas Andreou | Authors: Elif Gediz Kocaoglan, Andreas Andreou, Jessica Nirkko, Marisol Ochoa-Villarreal, Gary Loake and Naomi Nakayama | Summary: Plants are the primary biological platforms for producing food, energy, and materials in agriculture; however, they remain a minor player in the recent synthetic biology-driven transformation in bioproduction. Molecular tools and technologies for […]
Kavli Affiliate: Dwight Bergles | Authors: Christa Whelan Habela, Shiyu Liu, Arens Taga, Raha Dastgheyb, Norman Haughey, Dwight E Bergles, Hongjun Song, Guo-Li Ming and Nicholas J. Maragakis | Summary: The chromosome 15q11.2 locus is deleted in 1.5% of patients with genetic epilepsy and confers a risk for intellectual disability and schizophrenia. Individuals with this […]